Formation and distribution of NNK metabolites in an isolated perfused rat lung

Drug Metabolism and Disposition

Volumn 38, Issue 5, 2010, Pages 752-760

  Maertens, Laura A ^a   Upadhyaya, Pramod ^b   Hecht, Stephen S ^b   Zimmerman, Cheryl L ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANOL; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; CARCINOGEN; DNA; PHENETHYL ISOTHIOCYANATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER RISK; CHEMICAL STRUCTURE; CHEMOPROPHYLAXIS; COVALENT BOND; DETOXIFICATION; DNA ADDUCT; DNA ISOLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LUNG CANCER; LUNG CLEARANCE; LUNG HOMOGENATE; LUNG PARENCHYMA; LUNG PERFUSION; MALE; METABOLIC ACTIVATION; METABOLITE; NONHUMAN; PRIORITY JOURNAL; RAT; TOBACCO;

ANIMALS; CYCLIC N-OXIDES; DNA ADDUCTS; ENZYME INHIBITORS; ISOTHIOCYANATES; KETO ACIDS; LUNG; MALE; METABOLISM; NITROSAMINES; PERFUSION; PYRIDINES; RATS; RATS, INBRED F344;

NICOTIANA TABACUM; RATTUS;

EID: 77950927325     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.109.031492     Document Type: Article

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