PPARß activation inhibits melanoma cell proliferation involving repression of the Wilms' tumour suppressor WT1

Pflugers Archiv European Journal of Physiology

Volumn 459, Issue 5, 2010, Pages 689-703

  Michiels, Jean François ^a,b   Perrin, Christophe ^a,b   Leccia, Nathalie ^a,b   Massi, Daniela ^c   Grimaldi, Paul ^a,d   Wagner, Nicole ^a,d  

^a UNIVERSITÉ CÔTE D'AZUR   (France)

^b UNIVERSITY HOSPITAL OF NICE   (France)

^c UNIVERSITY OF FLORENCE   (Italy)

^d INSERM   (France)

Author keywords

Cancer cells; Melanoma; PPAR ; Proliferation; Skin cell line; Transcriptional regulation; Tumour immunohistochemistry; WT1

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; [4 [2 (3 FLUORO 4 TRIFLUOROMETHYLPHENYL) 4 METHYL 5 THIAZOLYLMETHYLTHIO] 2 METHYLPHENOXY]ACETIC ACID; NESTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; WT1 PROTEIN; ZYXIN;

ANIMAL CELL; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; DOWNSTREAM PROCESSING; ENZYME ACTIVATION; ENZYME REPRESSION; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; MELANOMA CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; AGED; ANIMAL; CLASSIFICATION; FEMALE; GENE EXPRESSION REGULATION; MALE; MELANOMA; METABOLISM; MIDDLE AGED; PHYSIOLOGY; SKIN; TUMOR CELL LINE;

AGED; AGED, 80 AND OVER; ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MELANOMA; MICE; MIDDLE AGED; PPAR-BETA; SKIN; WT1 PROTEINS;

EID: 77950920610     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-009-0776-6     Document Type: Article

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