Differential expression of peroxisome proliferator-activated receptors (PPARs) in the developing human fetal digestive tract

Journal of Histochemistry and Cytochemistry

Volumn 48, Issue 5, 2000, Pages 603-611

  Huin, Cécile ^a   Corriveau, Lina ^b   Bianchi, Arnaud ^a   Keller, Jean Marie ^a   Collet, Philippe ^a   Krémarik Bouillaud, Pascaline ^a   Domenjoud, Lionel ^a   Bécuwe, Philippe ^a   Schohn, Hervé ^a   Ménard, Daniel ^b   Dauça, Michel ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

^b UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

Development; Differentiation; Digestive tract; Fetus; PPARs

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR;

ARTICLE; CELL DIFFERENTIATION; ENDODERM; FETUS; GASTROINTESTINAL TRACT; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MESODERM; MORPHOGENESIS; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

MAMMALIA;

EID: 17544387857     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215540004800504     Document Type: Article

References (47)

1. Auboeuf D, Rieusset J, Fajas L, Vallier P, Freing V, Riou JP, Laville M, Staels B, Auwerx J, Vidal H (1997) Tissue distribution and quantification of the expression of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients. Diabetes 46:1319-1327
2. Avrameas S (1969) Coupling of enzymes to protein with glutaraldehyde. Use of the conjugates for the detection of antigens and antibodies. Immunochemistry 6:43-52
3. Basque JR, Levy E, Beaulieu JF, Ménard D (1998) Apolipoproteins in human fetal colon: immunolocalization, biogenesis, and hormonal regulation. J Cell Biochem 70:354-365
4. Bradford MM (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle-dye binding. Anal Biochem 72:248-254
5. Braissant O, Foufelle F, Scotto C, Dauça M, Wahli W (1996) Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-α, -β, and -γ in the adult rat. Endocrinology 137:354-366
6. Braissant O, Wahli W (1998) Differential expression of peroxisome proliferator-activated receptor -α, -β, -γ during rat embryonic development. Endocrinology 139:2748-2754
7. Brockman JA, Gupta RA, Dubois RN (1998) Activation of PPARγ leads to inhibition of anchorage-independent growth of human colorectal cancer cells. Gastroenterology 115:1049-1055
8. Chawla A, Schwarz EJ, Dimaculangan DD, Lazar MA (1994) Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation. Endocrinology 135:798-800
9. Chomzynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
10. Dauça M, Cablé S, Calvert R, Colin S, Schilt J, Leheup B, Keller JM, Ménard D (1996) Peroxisomes and peroxisomal enzymes in the human fetal small intestine. Biol Neonate 69:12-21
11. De Lomos (1977) The ultrastructure of endocrine cells in the corpus of the stomach of human fetuses. Am J Anat 148:359-384
12. Desvergne B, Wahli W (1995) PPAR: a key nuclear factor in nutrient/gene interactions? In Baeuerle P, ed. Inducible Transcription. Vol 1. Boston, Birkhaüsser, 142-176
13. Dubois RN, Gupta R, Brockman J, Reddy BS, Krakow SL, Lazar MA (1998) The nuclear eicosanoid receptor, PPARγ, is aberrantly expressed in colonie cancers. Cancerogenesis 19:49-53
14. 2. Biochem Biophys Res Commun 224:431-437
15. Fajas L, Auboeuf D, Raspe E, Schoonjans K, Lefebvre AM, Saladin R, Najib J, Fruchart JC, Deeb S, Vidal-Puig A, Flier J, Briggs MR, Staels B, Vidal H, Auwerx J (1997) The organisation, promoter analysis, and expression of the human PPAR gamma gene. J Biol Chem 272:18779-18789
16. Fajas L, Fruchart JC, Auwerx J (1998) PPARgamma3 mRNA: a distinct PPARgamma mRNA subtype transcribed from an independent promoter. FEBS Lett 438:55-60
17. Johns BAE (1952) Developmental changes in the oesophageal epithelium in man. J Anat 86:431-442
18. Lee SS, Pineau T, Drago J, Lee EJ, Owens JW, Kroetz DL, Fernandez-Salguero PM, Westphal H, Gonzalez FJ (1995) Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol 15:3012-3022
19. + mice. Nature Med 4:1053-1057
20. Lemberger T, Desvergne B, Wahli W (1996) Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology. Annu Rev Cell Dev Biol 12:335-363
21. Levy F, Thibault L, Ménard D (1992) Intestinal lipids and lipoproteins in the human fetus: modulation by epidermal growth factor. J Lipid Res 33:1607-1617
22. Mansen A, Guardiola-Diaz H, Rafter J, Branting C, Gustafsson JA (1996) Expression of the peroxisome proliferator-activated receptor (PPAR) in the mouse colonie mucosa. Biochem Biophys Res Commun 222:844-851
23. Martin G, Schoonjans K, Lefebvre AM, Staels B, Auwerx J (1997) Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARα and PPARγ activators. J Biol Chem 272:28210-28217
24. Marx N, Sukhova G, Murphy C, Libby P, Plutzky J (1998) Macrophages in human atheroma contain PPAR gamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma (PPAR gamma) expression and reduction of MMP-9 activity Through PPAR gamma activation in mononuclear phagocytes in vitro. Am J Pathol 153:17-23
25. Ménard D (1994) Development of human intestinal and gastric enzymes. Acta Paediatr 405:1-6
26. Ménard D (1995) Morphological studies of the developing human esophageal epithelium. Microsc Res Tech 31:215-225
27. Ménard D, Calvert R (1991) Fetal and postnatal development of the small and large intestine: patterns and regulation. In Morisset J, Solomon TE, eds. Growth of the Gastrointestinal Tract: Gastrointestinal Hormones and Growth Factors. Boca Raton, FL, CRC Press, 159-174
28. Montgomery RK, Mulberg AE, Grand RJ (1999) Development of the human gastrointestinal tract: twenty years of progress. Gastroenterology 116:702-731
29. Motojima K, Passilly P, Peters JM, Gonzalez FJ, Latruffe N (1998) Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor α and γ activators in a tissue- and inducer-specific manner. J Biol Chem 273: 16710-16714
30. Mukherjee R, Jow L, Noonan D, McDonnell DP (1994) Human and rat peroxisome proliferator-activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators. J Steroid Biochem Mol Biol 51:157-166
31. Ricote M, Huang J, Fajas L, Li A, Welch J, Najib J, Witztum JL, Auwerx J, Palinski W, Glass CK (1998) Expression of the peroxisome proliferator-activated receptor gamma (PPAR gamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc Natl Acad Sci USA 95:7614-7619
32. Saez E, Tontonoz P, Nelson MC, Alvarez JGA, U TM, Baird SM, Thomazy VA, Evans RM (1998) Activators of the nuclear receptor PPARγ enhance colon polyp formation. Nature Med 4:1058-1061
33. Salenius P (1962) On the ontogenesis of the human gastric epithelial cells. Acta Anat (Basel) 46:1-75
34. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular Cloning, a Laboratory Manual. 2nd ed. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press
35. Sarraf P, Mueller E, Jones D, King FJ, De Angelo DJ, Partridge JB, Holden SA, Chen LB, Singer S, Fletcher C, Spiegelman BM (1998) Differentiation and reversal of malignant changes in colon cancer through PPARγ. Nature Med 4:1046-1052
36. Schmidt A, Endo N, Rutledge SJ, Vogel R, Shinar D, Rodan GA (1992) Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids. Mol Endocrinol 6:1634-1641
37. Schoonjans K, Staels B, Auwerx J (1996) The peroxisome proliferator-activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation. Biochim Biophys Acta 1302: 93-109
38. Sher T, Yi HF, McBride OW, Gonzalez FJ (1993) cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator-activated receptor. Biochemistry 32:5598-5604
39. Sørensen HN, Treuter E, Gustafsson JA (1998) Regulation of peroxisome proliferator-activated receptors. Vitam Horm 54:121-166
40. Spiegelman BM (1998) PPAR gamma in monocytes: less pain, any gain? Cell 93:153-155
41. Spiegelman BM, Hu E, Kim JB, Brun R (1997) PPAR gamma and the control of adipogenesis. Biochimie 79:111-112
42. Tontonoz P, Hu E, Graves RA, Budavari AI, Spiegelman BM (1994) mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev 8:1224-1234
43. Tontonoz P, Hu E, Spiegelman BM (1995) Regulation of adipocyte gene expression and differentiation by peroxisome proliferator-activated receptor gamma. Curr Opin Genet Dev 5:571-576
44. Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM (1998) PPAR gamma promotes monocyre/macrophage differentiation and uptake of oxidized LDL. Cell 93:241-252
45. Tso JY, Sun XH, Kao TH, Reece KS, Wu R (1985) Isolation and characterization of rat and human glyceraldehycle-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic Acids Res 13:2485-2502
46. Wahli W, Braissant O, Desvergne B (1995) Peroxisome proliferator-activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more. Chem Biol 2:261-266
47. Zhu Y, Alvares K, Huang Q, Rao MS, Reddy JK (1993) Cloning of a new member of the peroxisome proliferator-activated receptor. J Biol Chem 268:26817-26820