Role of zyxin in differential cell spreading and proliferation of melanoma cells and melanocytes

Journal of Investigative Dermatology

Volumn 118, Issue 2, 2002, Pages 246-254

  Van der Gaag, Ellen J ^a,b   Leccia, Marie Thérèse ^c   Dekker, Sybren K ^b   Jalbert, Nicole L ^a   Amodeo, Dana M ^a   Byers, H Randolph ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LEIDEN UNIVERSITY   (Netherlands)

^c HÔPITAL MICHALLON   (France)

Author keywords

Actins; Cell differentiation; Extracellular matrix; Focal adhesion kinase; Paxillin; Phorbol esters

Indexed keywords

ACTIN; FOCAL ADHESION KINASE; INTEGRIN; PAXILLIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOPROTEIN; SCLEROPROTEIN; ZYXIN;

ADHESION; ARTICLE; CANCER GROWTH; CELL DIFFERENTIATION; CELL GROWTH; CELL LINE; CELL PROLIFERATION; CELL SPREADING; CELL SURVIVAL; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MELANOCYTE; MELANOMA CELL; MODULATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

EID: 0036175108     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-202x.2001.01657.x     Document Type: Article

References (44)

1. Focal adhesion kinase (p125 FAK) expression correlates with motility of human melanoma cell lines
2. Growth of human melanocyte cultures supported by 12-O-tetradecanoylphorbol-13-acetate is mediated through protein kinase C activation
3. Growth inhibition of human melanoma-derived cells by 12-O-tetradecanoyl phorbol 13-acetate
4. Differential expression of protein kinase C and cAMP-dependent protein kinase in normal human melanocytes and malignant melanomas
5. Identification of a new protein localized at sites of cell-substrate adhesion
6. Zyxin: Zinc fingers at sites of cell adhesion
7. Experimental metastasis and differentiation of murine melanoma cells: Actions and interactions of factors affecting different intracellular signalling pathways
8. Differential induction of 12-O-tetradecanoylphorbol-13-acetate sequence gene expression in murine melanocytes and melanoma cells
9. Focal adhesions, contractility, and signalling
10. Cell migration and actin organization in cultured human primary, recurrent cutaneous and metastatic melanoma
11. Organ-specific metastases in immunodeficient mice injected with human melanoma cells: A quantitative pathological analysis
12. Geometric control of cell life and death
13. 12-O-tetradecanoylphorbol-13-acetate induces transient cell cycle arrest in G1 and G2 in metastatic melanoma cells: Inhibition of phosphorylation of p34cdc2
14. Purification and characterization of zyxin, an 82,000-dalton component of adherens junctions
15. An interaction between zyxin and alpha-actinin
16. Biochemical and molecular characterization of the chicken cysteine-rich protein, a developmentally regulated LIM-domain protein that is associated with the actin cytoskeleton
17. Differential effects of interleukin 1-alpha (IL-1 alpha) or tumor necrosis factor-alpha (TNF-alpha) on motility of human melanoma cell lines on fibronectin
18. Role of integrin alpha 2 beta 1 (VLA-2) in the migration of human melanoma cells on laminin and type IV collagen
19. Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-11
20. Selective cultivation of human melanocytes from newborn and adult epidermis
21. Structural and functional similarities between the human cytoskeletal protein zyxin and the ActA protein of Listeria monocytogenes
22. Human melanocytes cultured from nevi and melanomas
23. SH3 domain-dependent interaction of the proto-oncogene product Vav with the focal contact protein zyxin
24. Association of type 3 protein kinase C with focal contacts in rat embryo fibroblasts
25. Zyxin redistributes without upregulation in migrating human keratinocytes during wound healing
26. Phorbol ester induced rapid attachment and spreading of melanoma cells and the role of extracellular matrix proteins
27. Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation
28. Characterization of a human cDNA encoding a widely expressed and highly conserved cysteine-rich protein with an unusual zinc-finger motif
29. Molecular characterization of human zyxin
30. T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells
31. Pigment content of cultured human melanocytes does not correlate with tyrosine message level
32. The family of protein kinase C for signal transduction
33. Protein kinase C and lipid signaling for sustained cellular responses
34. Nuclear-cytoplasmic shuttling of the focal contact protein, zyxin: A potential mechanism for communication between sites of cell adhesion and the nucleus
35. The beta isoform of protein kinase C stimulates human melanogenesis by activating tyrosinase in pigment cells
36. Identification, purification, and characterization of a zyxin-related protein that binds the focal adhesion and microfilament protein VASP (vasodilator-stimulated phosphoprotein)
37. Stretching is good for a cell
38. Zyxin and cCRP: Two interactive LIM domain proteins associated with the cytoskeleton
39. The LIM domain is a modular protein-binding interface
40. Bidirectional signaling between the cytoskeleton and integrins
41. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
42. Role of beta-1 integrins in organ specific adhesion of melanoma cells in vitro
43. Monoclonal antibody and synthetic peptide inhibitors of human tumor cell migration
44. Downregulation of protein kinase C is due to an increased rate of degradation