Formulation and release behavior of doxycycline-alginate hydrogel microparticles embedded into pluronic F127 thermogels as a potential new vehicle for doxycycline intradermal sustained delivery

AAPS PharmSciTech

Volumn 11, Issue 1, 2010, Pages 212-220

  Giovagnoli, Stefano ^a   Tsai, Tsuimin ^b   Deluca, Patrick P ^c  

^a UNIVERSITY OF PERUGIA   (Italy)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c University of Kentucky   (United States)

Author keywords

Doxycycline; Hydrogel microparticles; Sustained release; Thermogel

Indexed keywords

ALGINIC ACID; DOXYCYCLINE; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; POLOXAMER;

ARTICLE; CONTROLLED STUDY; CROSS LINKING; DISPERSION; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG SOLUBILITY; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEL; INTRADERMAL DRUG ADMINISTRATION; MEMBRANE MICROPARTICLE; PARTICLE SIZE; PRIORITY JOURNAL; SUSTAINED RELEASE FORMULATION; THERMOSTABILITY; ULTRAVIOLET RADIATION;

ALGINATES; CHEMISTRY, PHARMACEUTICAL; DOSAGE FORMS; DOXYCYCLINE; GELS; GLUCURONIC ACID; HEXURONIC ACIDS; HYDROGEL; INJECTIONS, INTRADERMAL; METHYLCELLULOSE; POLOXAMER; VEHICLES;

EID: 77950917460     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-009-9361-8     Document Type: Article

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