Partitioning of exhaled NO in ventilated patients undergoing cardiac surgery

Respiratory Physiology and Neurobiology

Volumn 171, Issue 2, 2010, Pages 151-156

  Tadié, Jean Marc ^a,b   Zegdi, Rachid ^a,b   Trinquart, Ludovic ^a,b   Kurdi, Okba ^b   Journois, Didier ^a,b   Latremouille, Christian ^a,b   Diehl, Jean Luc ^a,b   Louis, Bruno ^c   Fagon, Jean Yves ^a,b   Fabiani, Jean Noël ^a,b   Delclaux, Christophe ^a,b,d  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^c FACULTÉ DE MÉDECINE   (France)

^d HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

Cardio pulmonary bypass; Exhaled nitric oxide; Nasal nitric oxide; Positive end expiratory pressure

Indexed keywords

EXHALED NITRIC OXIDE; NITRIC OXIDE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ADULT; AGED; ARTERIAL OXYGEN TENSION; ARTICLE; ARTIFICIAL VENTILATION; BRONCHUS; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; FEMALE; HUMAN; LUNG ALVEOLUS; LUNG DEAD SPACE; MALE; POSITIVE END EXPIRATORY PRESSURE; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; SURGICAL PATIENT; COMPARATIVE STUDY; EXHALATION; HEART SURGERY; LUNG INJURY; METABOLISM; MIDDLE AGED; PROCEDURES; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BRONCHI; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; EXHALATION; FEMALE; HUMANS; LUNG INJURY; MALE; MIDDLE AGED; NITRIC OXIDE; POSITIVE-PRESSURE RESPIRATION; PULMONARY ALVEOLI; RESPIRATION, ARTIFICIAL; RESPIRATORY DEAD SPACE;

EID: 77950880389     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2010.02.010     Document Type: Article

References (39)

1. Altmay E., Karaca P., Yurtseven N., Ozkul V., Aksoy T., Ozler A., and Canik S. Continuous positive airway pressure does not improve lung function after cardiac surgery. Can. J. Anaesth. 53 (2006) 919-925
2. Attalah H.L., Honore S., Eddahibi S., Marcos E., Soussy C.J., Adnot S., and Delclaux C. Decreased exhaled nitric oxide as a marker of postinsult immune paralysis. J. Appl. Physiol. 97 (2004) 1188-1194
3. Beghetti M., Silkoff P.E., Caramori M., Holtby H.M., Slutsky A.S., and Adatia I. Decreased exhaled nitric oxide may be a marker of cardiopulmonary bypass-induced injury. Ann. Thorac. Surg. 66 (1998) 532-534
4. Brett S.J., Quinlan G.J., Mitchell J., Pepper J.R., and Evans T.W. Production of nitric oxide during surgery involving cardiopulmonary bypass. Crit. Care Med. 26 (1998) 272-278
5. Condorelli P., Shin H.W., Aledia A.S., Silkoff P.E., and George S.C. A simple technique to characterize proximal and peripheral nitric oxide exchange using constant flow exhalations and an axial diffusion model. J. Appl. Physiol. 102 (2007) 417-425
6. Condorelli P., Shin H.W., and George S.C. Characterizing airway and alveolar nitric oxide exchange during tidal breathing using a three-compartment model. J. Appl. Physiol. 96 (2004) 1832-1842
7. Cuthbertson B.H., Stott S.A., and Webster N.R. Exhaled nitric oxide as a marker of lung injury in coronary artery bypass surgery. Br. J. Anaesth. 89 (2002) 247-250
8. D'Angelo E., Koulouris N.G., Della Valle P., Gentile G., and Pecchiari M. The fall in exhaled nitric oxide with ventilation at low lung volumes in rabbits: an index of small airway injury. Respir. Physiol. Neurobiol. 160 (2008) 215-223
9. D'Angelo E., Pecchiari M., Baraggia P., Saetta M., Balestro E., and Milic-Emili J. Low-volume ventilation causes peripheral airway injury and increased airway resistance in normal rabbits. J. Appl. Physiol. 92 (2002) 949-956
10. D'Angelo E., Pecchiari M., Della Valle P., Koutsoukou A., and Milic-Emili J. Effects of mechanical ventilation at low lung volume on respiratory mechanics and nitric oxide exhalation in normal rabbits. J. Appl. Physiol. 99 (2005) 433-444
11. Delclaux C., Mahut B., Zerah-Lancner F., Delacourt C., Laoud S., Cherqui D., Duvoux C., Mallat A., and Harf A. Increased nitric oxide output from alveolar origin during liver cirrhosis versus bronchial source during asthma. Am. J. Respir. Crit. Care Med. 165 (2002) 332-337
12. Gal J., Kovesi T., Royston D., and Marczin N. Dynamics of nitroglycerin-induced exhaled nitric oxide after lung transplantation: evidence of pulmonary microvascular injury?. J. Heart Lung Transplant. 26 (2007) 1300-1305
13. George S.C., Hogman M., Permutt S., and Silkoff P.E. Modeling pulmonary nitric oxide exchange. J. Appl. Physiol. 96 (2004) 831-839
14. Groeneveld A.B., Jansen E.K., and Verheij J. Mechanisms of pulmonary dysfunction after on-pump and off-pump cardiac surgery: a prospective cohort study. J. Cardiothorac. Surg. 2 (2007) 11
15. Hill G.E., Snider S., Galbraith T.A., Forst S., and Robbins R.A. Glucocorticoid reduction of bronchial epithelial inflammation during cardiopulmonary bypass. Am. J. Respir. Crit. Care Med. 152 (1995) 1791-1795
16. Hubert D., Aubourg F., Fauroux B., Trinquart L., Sermet I., Lenoir G., Clement A., Dinh-Xuan A.T., Louis B., Mahut B., and Delclaux C. Exhaled NO in cystic fibrosis: relationships with airway and lung vascular impairments. Eur. Respir. J. 34 (2009) 117-124
17. Humpl T., Campbell R., Stephens D., Van Arsdell G., Benson L.N., Holtby H.M., Slutsky A.S., and Adatia I. Levels of exhaled nitric oxide before and after surgical and transcatheter device closure of atrial septal defects in children. J. Thorac. Cardiovasc. Surg. 124 (2002) 806-810
18. Imura H., Caputo M., Lim K., Ochi M., Suleiman M.S., Shimizu K., and Angelini G.D. Pulmonary injury after cardiopulmonary bypass: beneficial effects of low-frequency mechanical ventilation. J. Thorac. Cardiovasc. Surg. 137 (2009) 1530-1537
19. Ishibe Y., Liu R., Hirosawa J., Kawamura K., Yamasaki K., and Saito N. Exhaled nitric oxide level decreases after cardiopulmonary bypass in adult patients. Crit. Care Med. 28 (2000) 3823-3827
20. Kondo R., Haniuda M., Yamanda T., Sato E., Fujimoto K., Kubo K., and Amano J. Effects of expiratory pressure on nitric oxide in exhaled breath. Is exhaled nitric oxide really unaffected by pressure?. Respir. Physiol. Neurobiol. 139 (2003) 33-40
21. Kovesi T., Royston D., Yacoub M., and Marczin N. Basal and nitroglycerin-induced exhaled nitric oxide before and after cardiac surgery with cardiopulmonary bypass. Br. J. Anaesth. 90 (2003) 608-616
22. Kovesi T., Szabo A., Royston D., and Marczin N. Correlation between pulmonary gas exchange and basal and nitroglycerin (GTN)-induced exhaled nitric oxide (eNO) in patients undergoing cardiac surgery. Vascul. Pharmacol. 43 (2005) 434-440
23. Lehtimaki L., Kankaanranta H., Saarelainen S., Hahtola P., Jarvenpaa R., Koivula T., Turjanmaa V., and Moilanen E. Extended exhaled NO measurement differentiates between alveolar and bronchial inflammation. Am. J. Respir. Crit. Care Med. 163 (2001) 1557-1561
24. Lemaire F. Do all types of human research need ethics committee approval?. Am. J. Respir. Crit. Care Med. 174 (2006) 363-364
25. Loeckinger A., Kleinsasser A., Lindner K.H., Margreiter J., Keller C., and Hoermann C. Continuous positive airway pressure at 10 cm H(2)O during cardiopulmonary bypass improves postoperative gas exchange. Anesth. Analg. 91 (2000) 522-527
26. Mahut B., Louis B., Zerah-Lancner F., and Delclaux C. Validity criteria and comparison of analytical methods of flow-independent exhaled NO parameters. Respir. Physiol. Neurobiol. 153 (2006) 148-156
27. Mahut B., Peiffer C., Thibaudon M., Chevalier-Bidaud B., Defrance-Hutinet M.F., Trinquart L., and Delclaux C. What does a single exhaled nitric oxide measurement tell us in asthmatic children?. J. Asthma 46 (2009) 810-814
28. Malmstrom R.E., Tornberg D.C., Settergren G., Liska J., Angdin M., Lundberg J.O., and Weitzberg E. Endogenous nitric oxide release by vasoactive drugs monitored in exhaled air. Am. J. Respir. Crit. Care Med. 168 (2003) 114-120
29. Maniscalco M., de Laurentiis G., Zedda A., Faraone S., Giardiello C., Cristiano S., and Sofia M. Exhaled nitric oxide in severe obesity: effect of weight loss. Respir. Physiol. Neurobiol. 156 (2007) 370-373
30. Marczin N., Riedel B., Gal J., Polak J., and Yacoub M. Exhaled nitric oxide during lung transplantation. Lancet 350 (1997) 1681-1682
31. Ng C.S., Arifi A.A., Wan S., Ho A.M., Wan I.Y., Wong E.M., and Yim A.P. Ventilation during cardiopulmonary bypass: impact on cytokine response and cardiopulmonary function. Ann. Thorac. Surg. 85 (2008) 154-162
32. Pearl J.M., Nelson D.P., Wellmann S.A., Raake J.L., Wagner C.J., McNamara J.L., and Duffy J.Y. Acute hypoxia and reoxygenation impairs exhaled nitric oxide release and pulmonary mechanics. J. Thorac. Cardiovasc. Surg. 119 (2000) 931-938
33. Persson M.G., Lonnqvist P.A., and Gustafsson L.E. Positive end-expiratory pressure ventilation elicits increases in endogenously formed nitric oxide as detected in air exhaled by rabbits. Anesthesiology 82 (1995) 969-974
34. Sartori C., Lepori M., Busch T., Duplain H., Hildebrandt W., Bartsch P., Nicod P., Falke K.J., and Scherrer U. Exhaled nitric oxide does not provide a marker of vascular endothelial function in healthy humans. Am. J. Respir. Crit. Care Med. 160 (1999) 879-882
35. Scherer M., Dettmer S., Meininger D., Deschka H., Geyer G., Regulla C., and Moritz A. Alveolar recruitment strategy during cardiopulmonary bypass does not improve postoperative gas exchange and lung function. Cardiovasc. Eng. 9 (2009) 1-5
36. Tornberg D.C., Angdin M., Settergen G., Liska J., Lundberg J.O., and Weitzberg E. Exhaled nitric oxide before and after cardiac surgery with cardiopulmonary bypass-response to acetylcholine and nitroglycerin. Br. J. Anaesth. 94 (2005) 174-180
37. Tornberg D.C., Bjorne H., Lundberg J.O., and Weitzberg E. Multiple single-breath measurements of nitric oxide in the intubated patient. Am. J. Respir. Crit. Care Med. 168 (2003) 1210-1215
38. Yeh C.H., Chen T.P., Lee C.H., Wu Y.C., Lin Y.M., and Lin P.J. Cardioplegia-induced cardiac arrest under cardiopulmonary bypass decreased nitric oxide production which induced cardiomyocytic apoptosis via nuclear factor kappa B activation. Shock 27 (2007) 422-428
39. Zegdi R., Fabre O., Cambillau M., Detruit H., Fornes P., Rajnoch C., Shen M., Herve P., Carpentier A., and Fabiani J.N. Exhaled nitric oxide does not reflect the severity of acute lung injury: an experimental study in a rat model of extracorporeal circulation. Crit. Care Med. 30 (2002) 2096-2102