Induction of IL-13 production and upregulation of gene expression of protease activated receptors in P815 cells by IL-6

Cytokine

Volumn 50, Issue 2, 2010, Pages 138-145

  Zhang, Huiyun ^b   Lin, Liyan ^c   Yang, Haiwei ^a   Zhang, Zhongfang ^c   Yang, Xiaoyu ^c   Zhang, Lianxia ^c   He, Shaoheng ^a,c  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b HAINAN MEDICAL UNIVERSITY   (China)

^c SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

IL 13; IL 6; Mast cell; Protease activated receptor; Tryptase

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEINASE ACTIVATED RECEPTOR; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 3; PROTEINASE ACTIVATED RECEPTOR 4; TRYPTASE;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL STRAIN; CELL STRAIN P815; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMAN; MAST CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CHROMONES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INTERLEUKIN-13; INTERLEUKIN-6; MAST CELLS; MICE; MORPHOLINES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RECEPTORS, PROTEINASE-ACTIVATED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TH2 CELLS; TRYPTASES; UP-REGULATION;

EID: 77950865955     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2010.02.006     Document Type: Article

References (48)

1. Yokoyama A., Kohno N., Sakai K., Kondo K., Hirasawa Y., Hiwada K. Circulating levels of soluble interleukin-6 receptor in patients with bronchial asthma. Am J Respir Crit Care Med 1997, 156:1688-1691.
2. Hollins F., Kaur D., Yang W., Cruse G., Saunders R., Sutcliffe A., et al. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J Immunol 2008, 181:2772-2780.
3. Conti P., Kempuraj D., Di Gioacchino M., Boucher W., Letourneau R., Kandere K., et al. Interleukin-6 and mast cells. Allergy Asthma Proc 2002, 23:331-335.
4. Kikuchi T., Ishida S., Kinoshita T., Sakuma S., Sugawara N., Yamashita T., et al. IL-6 enhances IgE-dependent histamine release from human peripheral blood-derived cultured mast cells. Cytokine 2002, 20:200-209.
5. Li T., Wang H., He S. Induction of interleukin-6 release from monocytes by serine proteinases and its potential mechanisms. Scand J Immunol 2006, 64:10-16.
6. Li T., He S. Induction of IL-6 release from human T cells by PAR-1 and PAR-2 agonists. Immunol Cell Biol 2006, 84:461-466.
7. Asokananthan N., Graham P.T., Fink J., Knight D.A., Bakker A.J., McWilliam A.S., et al. Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J Immunol 2002, 168:3577-3585.
8. Sundararaj K.P., Samuvel D.J., Li Y., Sanders J.J., Lopes-Virella M.F., Huang Y. Interleukin-6 released from fibroblasts is essential for up-regulation of matrix metalloproteinase-1 expression by U937 macrophages in coculture: cross-talking between fibroblasts and U937 macrophages exposed to high glucose. J Biol Chem 2009, 284:13714-13724.
9. Chi L., Li Y., Stehno-Bittel L., Gao J., Morrison D.C., Stechschulte D.J., et al. Interleukin-6 production by endothelial cells via stimulation of protease-activated receptors is amplified by endotoxin and tumor necrosis factor-alpha. J Interferon Cytokine Res 2001, 21:231-240.
10. Kandere-Grzybowska K., Kempuraj D., Cao J., Cetrulo C.L., Theoharides T.C. Regulation of IL-1-induced selective IL-6 release from human mast cells and inhibition by quercetin. Br J Pharmacol 2006, 148(2):208-215.
11. Cruse G., Cockerill S., Bradding P. IgE alone promotes human lung mast cell survival through the autocrine production of IL-6. BMC Immunol 2008, 9:2.
12. Prieto J., Lensmar C., Roquet A., van der Ploeg I., Gigliotti D., Eklund A., et al. Increased interleukin-13 mRNA expression in bronchoalveolar lavage cells of atopic patients with mild asthma after repeated low-dose allergen provocations. Respir Med 2000, 94(8):806-814.
13. Kaur D., Hollins F., Woodman L., Yang W., Monk P., May R., et al. Mast cells express IL-13R alpha 1: IL-13 promotes human lung mast cell proliferation and Fc epsilon RI expression. Allergy 2006, 61:1047-1053.
14. Bulanova E., Budagian V., Orinska Z., Hein M., Petersen F., Thon L., et al. Extracellular ATP induces cytokine expression and apoptosis through P2X7 receptor in murine mast cells. J Immunol 2005, 174:3880-3890.
15. Lorentz A., Klopp I., Gebhardt T., Manns M.P., Bischoff S.C. Role of activator protein 1, nuclear factor-kappaB, and nuclear factor of activated T cells in IgE receptor-mediated cytokine expression in mature human mast cells. J Allergy Clin Immunol 2003, 111:1062-1068.
16. Hong J., Sasaki H., Hirasawa N., Ishihara K., Kwak J.H., Zee O., et al. Suppression of the antigen-stimulated RBL-2H3 mast cell activation by artekeiskeanol A. Planta Med 2009, 75(14):1494-1498.
17. Tanemura S., Momose H., Shimizu N., Kitagawa D., Seo J., Yamasaki T., et al. Blockage by SP600125 of Fcepsilon receptor-induced degranulation and cytokine gene expression in mast cells is mediated through inhibition of phosphatidylinositol 3-kinase signalling pathway. J Biochem 2009, 145:345-354.
18. He S., Peng Q., Walls A.F. Potent induction of neutrophil- and eosinophilrich infiltrate in vivo by human mast cell tryptase: selective enhancement of eosinophil recruitment by histamine. J Immunol 1997, 159:6216-6225.
19. He S., Gaca M.D.A., Walls A.F. A role for tryptase in the activation of human mast cells: modulation of histamine release by tryptase and inhibitors of tryptase. J Pharmacol Exp Ther 1998, 286:289-297.
20. Kinoshita M., Okada M., Hara M., Furukawa Y., Matsumori A. Mast cell tryptase in mast cell granules enhances MCP-1 and interleukin-8 production in human endothelial cells. Arterioscler Thromb Vasc Biol 2005, 25:1858-1863.
21. He S.H., Xie H., Fu Y.L. Activation of human tonsil and skin mast cells by agonists of proteinase activated receptor-2. Acta Pharmacol Sin 2005, 26:568-574.
22. Zhang H., Yang X., Yang H., Zhang Z., Lin Q., Zheng Y., et al. Modulation of mast cell proteinase-activated receptor expression and IL-4 release by IL-12. Immunol Cell Biol 2007, 85:558-566.
23. Wang H., He S. Induction of lactoferrin and IL-8 release from human neutrophils by tryptic enzymes via proteinase activated receptor-2. Cell Biol Int 2006, 30:688-697.
24. Nickel T.J., Kabir M.H., Talreja J., Stechschulte D.J., Dileepan K.N. Constitutive expression of functionally active protease-activated receptors 1 and 2 in human conjunctival epithelial cells. Mediat Inflamm 2006, 2006(3):61359.
25. Zhang H., Yang H., Zhang L., Yang X., Zhang Z., Lin Q., et al. Induction of IL-4 release and upregulated expression of protease activated receptors by GM-CSF in P815 cells. Cytokine 2009, 48(3):196-202.
26. Qiao L., Zhang H., Wu S., He S. Downregulation of protease activated receptor expression and cytokine production in P815 cells by RNA interference. BMC Cell Biol 2009, 10:62.
27. Castellani M.L., Perrella A., Kempuraj D.J., Boucher W., Tagen M., Salini V., et al. Immunological activation of human umbilical cord blood mast cells induces tryptase secretion and interleukin-6, and histidine decarboxilase mRNA gene expression. Pharmacol Res 2007, 55:57-63.
28. Moulin D., Donzé O., Talabot-Ayer D., Mézin F., Palmer G., Gabay C. Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells. Cytokine 2007, 40:216-225.
29. Hershey G.K. IL-13 receptors and signaling pathways: an evolving web. J Allergy Clin Immunol 2003, 111:677-690.
30. Neveu W.A., Allard J.B., Dienz O., Wargo M.J., Ciliberto G., Whittaker L.A., et al. IL-6 is required for airway mucus production induced by inhaled fungal allergens. J Immunol 2009, 183:1732-1738.
31. Kobayashi H., Okayama Y., Ishizuka T., Pawankar R., Ra C., Mori M. Production of IL-13 by human lung mast cells in response to Fcepsilon receptor cross-linkage. Clin Exp Allergy 1998, 28:1219-1227.
32. Toru H., Pawankar R., Ra C., Yata J., Nakahata T. Human mast cells produce IL-13 by high-affinity IgE receptor cross-linking: enhanced IL-13 production by IL-4-primed human mast cells. J Allergy Clin Immunol 1998, 102:491-502.
33. Iikura M., Suto H., Kajiwara N., Oboki K., Ohno T., Okayama Y., et al. IL-33 can promote survival, adhesion and cytokine production in human mast cells. Lab Invest 2007, 87:971-978.
34. Zhang Z., Zhang H., Yang H., Zhang L., Chen X., Zheng X., et al. Induction of T-helper type 2 cytokine release and up-regulated expression of protease-activated receptors on mast cells by recombinant American cockroach allergen Per a 7. Clin Exp Allergy 2008, 38:1160-1167.
35. Yang H., Wei J., Zhang H., Lin L., Zhang W., He S. Upregulation of Toll-like receptor (TLR) expression and release of cytokines from P815 mast cells by GM-CSF. BMC Cell Biol 2009, 10:37.
36. Wong G.W., Foster P.S., Yasuda S., Qi J.C., Mahalingam S., Mellor E.A., et al. Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway. J Biol Chem 2002, 277:41906-41915.
37. Ebeling C., Forsythe P., Ng J., Gordon J.R., Hollenberg M., Vliagoftis H. Proteinase-activated receptor 2 activation in the airways enhances antigen-mediated airway inflammation and airway hyperresponsiveness through different pathways. J Allergy Clin Immunol 2005, 115:623-630.
38. Sin A.Z., Roche E.M., Togias A., Lichtenstein L.M., Schroeder J.T. Nerve growth factor or IL-3 induces more IL-13 production from basophils of allergic subjects than from basophils of nonallergic subjects. J Allergy Clin Immunol 2001, 108:387-393.
39. Bulanova E., Budagian V., Orinska Z., Koch-Nolte F., Haag F., Bulfone-Paus S. ATP induces P2X7 receptor-independent cytokine and chemokine expression through P2X1 and P2X3 receptors in murine mast cells. J Leukoc Biol 2009, 85:692-702.
40. Holen E., Bolann B., Elsayed S. Novel B and T cell epitopes of chicken ovomucoid (Gal d 1) induce T cell secretion of IL-6, IL-13, and IFN-gamma. Clin Exp Allergy 2001, 31:952-964.
41. Doganci A., Eigenbrod T., Krug N., De Sanctis G.T., Hausding M., Erpenbeck V.J., et al. The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo. J Clin Invest 2005, 115:313-325.
42. Nishimoto N., Kanakura Y., Aozasa K., Johkoh T., Nakamura M., Nakano S., et al. Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease. Blood 2005, 106:2627-2632.
43. Freund-Michel V., Frossard N. Inflammatory conditions increase expression of protease-activated receptor-2 by human airway smooth muscle cells in culture. Fundam Clin Pharmacol 2006, 20:351-357.
44. Ritchie E., Saka M., Mackenzie C., Drummond R., Wheeler-Jones C., Kanke T., et al. Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase beta in human endothelial cells. Br J Pharmacol 2007, 150:1044-1054.
45. Ramachandran R., Sadofsky L.R., Xiao Y., Botham A., Cowen M., Morice A.H., et al. Inflammatory mediators modulate thrombin and cathepsin-G signaling in human bronchial fibroblasts by inducing expression of proteinase-activated receptor-4. Am J Physiol Lung Cell Mol Physiol 2007, 292:L788-L798.
46. Frasca D., Landin A.M., Alvarez J.P., Blackshear P.J., Riley R.L., Blomberg B.B. Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA. J Immunol 2007, 179:918-927.
47. Kuwahara I., Lillehoj E.P., Lu W., Singh I.S., Isohama Y., Miyata T., et al. Neutrophil elastase induces IL-8 gene transcription and protein release through p38/NF-{kappa}B activation via EGFR transactivation in a lung epithelial cell line. Am J Physiol Lung Cell Mol Physiol 2006, 291:L407-L416.
48. Esnault S., Malter J.S. Hyaluronic acid or TNF-alpha plus fibronectin triggers granulocyte macrophage-colony-stimulating factor mRNA stabilization in eosinophils yet engages differential intracellular pathways and mRNA binding proteins. J Immunol 2003, 171:6780-6787.