Total alkaloids from Radix Linderae prevent the production of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 cells by suppressing NF-κB and MAPKs activation

Cytokine

Volumn 46, Issue 1, 2009, Pages 104-110

  Luo, Yubin ^a   Liu, Mei ^a   Yao, Xiujuan ^a   Xia, Yufeng ^a   Dai, Yue ^a   Chou, Guixin ^b   Wang, Zhengtao ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Macrophages; MAPK; NF B; Proinflammatory cytokines; TARL

Indexed keywords

ALKALOID; BACTERIUM LIPOPOLYSACCHARIDE; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LINDERA AGGREGATA EXTRACT; LINDERA STRYCHNIFOLIA EXTRACT; MACROPHAGE ACTIVATING FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PLANT EXTRACT; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; LINDERA; LINDERA AGGREGATA; LINDERA STRYCHNIFOLIA; MOUSE; NONHUMAN; PLANT ROOT; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION;

ALKALOIDS; ANIMALS; ARTHRITIS, RHEUMATOID; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; MODELS, BIOLOGICAL; NF-KAPPA B; PLANT EXTRACTS; RANUNCULACEAE;

ANIMALIA; LINDERA AGGREGATA;

EID: 62749122899     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2008.12.017     Document Type: Article

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