Differential polymerase activity in avian and mammalian cells determines host range of influenza virus

Journal of Virology

Volumn 81, Issue 17, 2007, Pages 9601-9604

  Gabriel, G ^a   Abram, M ^a   Keiner, B ^a   Wagner, R ^a,b   Klenk, H D ^a   Stech, J ^a,c  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b PAUL EHRLICH INSTITUT   (Germany)

^c FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; DNA POLYMERASE; MESSENGER RNA; VIRUS RNA;

ANIMAL CELL; ARTICLE; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME ANALYSIS; FOWL; HOST; HUMAN; HUMAN CELL; INFLUENZA VIRUS; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; QUAIL; VIRUS REPLICATION; VIRUS TRANSMISSION; VIRUS VIRULENCE;

ANIMALS; BIRDS; CELL LINE; CHICK EMBRYO; INFLUENZA A VIRUS, H7N7 SUBTYPE; MAMMALS; RNA REPLICASE; RNA, COMPLEMENTARY; RNA, MESSENGER; RNA, VIRAL; VIRAL PROTEINS;

AVES; AVIAN INFLUENZA VIRUS; MAMMALIA; MUS; ORTHOMYXOVIRIDAE;

EID: 34548169547     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00666-07     Document Type: Article

References (27)

1. Area, E., J. Martin-Benito, P. Gastaminza, E. Torreira, J. M. Valpuesta, J. L. Carrascosa, and J. Ortin. 2004. 3D structure of the influenza virus polymerase complex: localization of subunit domains. Proc. Natl. Acad. Sci. USA 101:308-313.
2. Claas, E. C., A. D. Osterhaus, R. van Beek, J. C. De Jong, G. F. Rimmelzwaan, D. A. Senne, S. Krauss, K. F. Shortridge, and R. G. Webster. 1998. Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus. Lancet 351:472-477.
3. Deng, T., O. G. Engelhardt, B. Thomas, A. V. Akoulitchev, G. G. Brownlee, and E. Fodor. 2006. The role of Ran binding protein 5 (RanBP5) in the nuclear import and assembly of the influenza virus RNA polymerase complex. J. Virol. 80:11911-11919.
4. Engelhardt, O. G., M. Smith, and E. Fodor. 2005. Association of the influenza A virus RNA-dependent RNA polymerase with cellular RNA polymerase II. J. Virol. 79:5812-5818.
5. Fodor, E., M. Crow, L. J. Mingay, T. Deng, J. Sharps, P. Fechter, and G. G. Brownlee. 2002. A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase inhibits endonucleolytic cleavage of capped RNAs. J. Virol. 76:8989-9001.
6. Fouchier, R. A., P. M. Schneeberger, F. W. Rozendaal, J. M. Broekman, S. A. Kemink, V. Munster, T. Kuiken, G. F. Rimmelzwaan, M. Schutten, G. J. Van Doornum, G. Koch, A. Bosman, M. Koopmans, and A. D. Osterhaus. 2004. Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome. Proc. Natl. Acad. Sci. USA 101:1356-1361.
7. Gabriel, G., B. Dauber, T. Wolff, O. Planz, H. D. Klenk, and J. Stech. 2005. The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host. Proc. Natl. Acad. Sci. USA 102:18590-18595.
8. Honda, A., K. Ueda, K. Nagata, and A. Ishihama. 1988. RNA polymerase of influenza virus: role of NP in RNA chain elongation. J. Biochem. (Tokyo) 104:1021-1026.
9. Horimoto, T., and Y. Kawaoka. 2005. Influenza: lessons from past pandemics, warnings from current incidents. Nat. Rev. Microbiol. 3:591-600.
10. Klenk, H. D., and R. Rott. 1988. The molecular biology of influenza virus pathogenicity. Adv. Virus Res. 34:247-281.
11. Labadie, K., E. Dos Santos Afonso, M. A. Rameix-Welti, S. van der Werf, and N. Naffakh. 2007. Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells. Virology 362:271-282.
12. Li, S. Q., M. Orlich, and R. Rott. 1990. Generation of seal influenza virus variants pathogenic for chickens, because of hemagglutinin cleavage site changes. J. Virol. 64:3297-3303.
13. Medcalf, L., E. Poole, D. Elton, and P. Digard. 1999. Temperature-sensitive lesions in two influenza A viruses defective for replicative transcription disrupt RNA binding by the nucleoprotein. J. Virol. 73:7349-7356.
14. Neumann, G., and Y. Kawaoka. 2006. Host range restriction and pathogenicity in the context of influenza pandemic. Emerg. Infect. Dis. 12:881-886.
15. Olsen, B., V. J. Munster, A. Wallensten, J. Waldenstrom, A. D. Osterhaus, and R. A. Fouchier. 2006. Global patterns of influenza A virus in wild birds. Science 312:384-388.
16. Peiris, M., K. Y. Yuen, C. W. Leung, K. H. Chan, P. L. Ip, R. W. Lai, W. K. Orr, and K. F. Shortridge. 1999. Human infection with influenza H9N2. Lancet 354:916-917.
17. Reed, L. H., and H. Muench. 1938. A simple method of estimating fifty percent endpoints. Am. J. Hyg. 27:493-497.
18. Scholtissek, C., and B. R. Murphy. 1978. Host range mutants of an influenza A virus. Arch. Virol. 58:323-333.
19. Shapiro, G. I., and R. M. Krug. 1988. Influenza virus RNA replication in vitro: synthesis of viral template RNAs and virion RNAs in the absence of an added primer. J. Virol. 62:2285-2290.
20. Snyder, M. H., A. J. Buckler-White, W. T. London, E. L. Tierney, and B. R. Murphy. 1987. The avian influenza virus nucleoprotein gene and a specific constellation of avian and human virus polymerase genes each specify attenuation of avian-human influenza A/Pintail/79 reassortant viruses for monkeys. J. Virol. 61:2857-2863.
21. Subbarao, E. K., W. London, and B. R. Murphy. 1993. A single amino acid in the PB2 gene of influenza A virus is a determinant of host range. J. Virol. 67:1761-1764.
22. Subbarao, K., A. Klimov, J. Katz, H. Regnery, W. Lim, H. Hall, M. Perdue, D. Swayne, C. Bender, J. Huang, M. Hemphill, T. Rowe, M. Shaw, X. Xu, K. Fukuda, and N. Cox. 1998. Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. Science 279:393-396.
23. Tarendeau, F., J. Boudet, D. Guilligay, P. J. Mas, C. M. Bougault, S. Boulo, F. Baudin, R. W. Ruigrok, N. Daigle, J. Ellenberg, S. Cusack, J. P. Simorre, and D. J. Hart. 2007. Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit. Nat. Struct. Mol. Biol. 14:229-233.
24. Tumpey, T. M., C. F. Basler, P. V. Aguilar, H. Zeng, A. Solorzano, D. E. Swayne, N. J. Cox, J. M. Katz, J. K. Taubenberger, P. Palese, and A. Garcia-Sastre. 2005. Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science 310:77-80.
25. Vreede, F. T., T. E. Jung, and G. G. Brownlee. 2004. Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates. J. Virol. 78:9568-9572.
26. Webster, R. G., W. J. Bean, O. T. Gorman, T. M. Chambers, and Y. Kawaoka. 1992. Evolution and ecology of influenza A viruses. Microbiol. Rev. 56:152-179.
27. Ye, Q., R. M. Krug, and Y. J. Tao. 2006. The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA. Nature 444:1078-1082.