-
1
-
-
33748275681
-
The p53 tumor suppressor participates in multiple cell cycle checkpoints
-
Giono L, Manfredi J. The p53 tumor suppressor participates in multiple cell cycle checkpoints. J Cell Physiol 2006;209:13-20.
-
(2006)
J Cell Physiol
, vol.209
, pp. 13-20
-
-
Giono, L.1
Manfredi, J.2
-
2
-
-
18344377030
-
The p53 pathway: Positive and negative feedback loops
-
Harris S, Levne A. The p53 pathway: positive and negative feedback loops. Oncogene 2005;24:2899-2908
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.1
Levne, A.2
-
3
-
-
0033992478
-
P53 and human cancer: The first ten thousand mutations
-
Hainaut P, Hollstein M. p53 and human cancer: the first ten thousand mutations. Adv Cancer Res 2000;77:81-137.
-
(2000)
Adv Cancer Res
, vol.77
, pp. 81-137
-
-
Hainaut, P.1
Hollstein, M.2
-
7
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev L, Vu B, Graves B, et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 2004;303:844-848
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.1
Vu, B.2
Graves, B.3
-
8
-
-
32444449180
-
Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: Implications for therapy
-
Tovar C, Rosinski J, Filipovic Z, et al. Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy. Proc Natl Acad Sci U S A 2006;103:1888-1893
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 1888-1893
-
-
Tovar, C.1
Rosinski, J.2
Filipovic, Z.3
-
9
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100: 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
10
-
-
0345731237
-
Cell migration: Rho GTPases lead the way
-
Raftopoulou M, Hall A. Cell migration: Rho GTPases lead the way. Dev Biol 2004;265:23-32.
-
(2004)
Dev Biol
, vol.265
, pp. 23-32
-
-
Raftopoulou, M.1
Hall, A.2
-
11
-
-
0344305784
-
Cell migration: Integrating signals from front to back
-
Ridley AJ, Schwartz MA, Burridge K, et al. Cell migration: integrating signals from front to back. Science 2003;302:1704-1709
-
(2003)
Science
, vol.302
, pp. 1704-1709
-
-
Ridley, A.J.1
Schwartz, M.A.2
Burridge, K.3
-
12
-
-
0038049137
-
Tumour-cell invasion and migration: Diversity and escape mechanisms
-
Friedl P, Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 2003;3:362-374
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 362-374
-
-
Friedl, P.1
Wolf, K.2
-
13
-
-
0042354574
-
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
-
Sahal E, Marshall C. Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat Cell Biol 2003;5:711-719
-
(2003)
Nat Cell Biol
, vol.5
, pp. 711-719
-
-
Sahal, E.1
Marshall, C.2
-
14
-
-
0034706902
-
Changes in p53 expression in mouse fibroblasts can modify motility and extracellular matrix organization
-
Alexandrova A, Ivanov A, Chumakov P, Kopnin B, Vaslllev J. Changes in p53 expression in mouse fibroblasts can modify motility and extracellular matrix organization. Oncogene 2000;19:5826-5830
-
(2000)
Oncogene
, vol.19
, pp. 5826-5830
-
-
Alexandrova, A.1
Ivanov, A.2
Chumakov, P.3
Kopnin, B.4
Vaslllev, J.5
-
15
-
-
0037093470
-
Regulation of Cdc42-medlated morphological effects: A novel function for p53
-
Gadéa G, Lapasset L, Gauthier-Rouvière C, Roux P. Regulation of Cdc42-medlated morphological effects: a novel function for p53. EMBO J 2002;21:2373-2382
-
(2002)
EMBO J
, vol.21
, pp. 2373-2382
-
-
Gadéa, G.1
Lapasset, L.2
Gauthier-Rouvière, C.3
Roux, P.4
-
16
-
-
0037900074
-
P19Arf-p53 tumor suppressor pathway regulates cell motility by suppression of phosphoinositide 3-kinase and Rac1 GTPase activities
-
Guo F, Gao Y, Wang L, Zheng Y. p19Arf-p53 tumor suppressor pathway regulates cell motility by suppression of phosphoinositide 3-kinase and Rac1 GTPase activities. J Biol Chem 2003;278:14414-14419
-
(2003)
J Biol Chem
, vol.278
, pp. 14414-14419
-
-
Guo, F.1
Gao, Y.2
Wang, L.3
Zheng, Y.4
-
17
-
-
3342893272
-
Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion
-
Guo F, Zheng Y. Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion. Oncogene 2004;23:5577-5585
-
(2004)
Oncogene
, vol.23
, pp. 5577-5585
-
-
Guo, F.1
Zheng, Y.2
-
18
-
-
34347382959
-
Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices
-
Gadea G, de Toledo M, Anguille C, Roux P. Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices. J Cell Biol 2007;178:23-30.
-
(2007)
J Cell Biol
, vol.178
, pp. 23-30
-
-
Gadea, G.1
De Toledo, M.2
Anguille, C.3
Roux, P.4
-
19
-
-
12344252751
-
Mechanisms of cancer cell invasion
-
Sahai E. Mechanisms of cancer cell invasion. Curr Opin Genet Dev 2005;15:87-96.
-
(2005)
Curr Opin Genet Dev
, vol.15
, pp. 87-96
-
-
Sahai, E.1
-
20
-
-
33750346173
-
Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma
-
Van Maerken T, Speleman F, Vermeulen J, et al. Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma. Cancer Res 2006;66:9646-9655
-
(2006)
Cancer Res
, vol.66
, pp. 9646-9655
-
-
Van Maerken, T.1
Speleman, F.2
Vermeulen, J.3
-
21
-
-
33846087742
-
Antlangiogenic activity of the MDM2 antagonist nutlin-3
-
Seechiero P, Corallini F, Gonelli A, et al. Antlangiogenic activity of the MDM2 antagonist nutlin-3. Circ Res 2007;100:61-69
-
(2007)
Circ Res
, vol.100
, pp. 61-69
-
-
Seechiero, P.1
Corallini, F.2
Gonelli, A.3
-
22
-
-
33845348208
-
P53 Attenuates cancer cell migration and invasion through repression of SDF-1/ CXCL12 expression in stromal fibroblasts
-
Moskovits N, Kalinkovich A, Bar J, Lapidot T, Oren M. p53 Attenuates cancer cell migration and invasion through repression of SDF-1/ CXCL12 expression in stromal fibroblasts. Cancer Res 2006;66: 10671-10676
-
(2006)
Cancer Res
, vol.66
, pp. 10671-10676
-
-
Moskovits, N.1
Kalinkovich, A.2
Bar, J.3
Lapidot, T.4
Oren, M.5
-
23
-
-
34147094240
-
The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: Regulation of Rho GTPase recruitment to the leading edge
-
Dow L, Kauffman J, Caddy J, et al. The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge. Oncogene 2007;26: 2272-2282
-
(2007)
Oncogene
, vol.26
, pp. 2272-2282
-
-
Dow, L.1
Kauffman, J.2
Caddy, J.3
-
24
-
-
32644448252
-
The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway
-
Kuo J, Wang W, Yao C, Wu P, Chen R. The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway. J Cell Biol 2006;172:619-631
-
(2006)
J Cell Biol
, vol.172
, pp. 619-631
-
-
Kuo, J.1
Wang, W.2
Yao, C.3
Wu, P.4
Chen, R.5
-
25
-
-
33751252276
-
Cancer metastasis: Building a framework
-
Gupta GP, Massague J. Cancer metastasis: building a framework. Cell 2006;127:679-695
-
(2006)
Cell
, vol.127
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
27
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001;410:50-56
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
-
28
-
-
0037085938
-
Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone
-
Taichman RS, Cooper C, Keller ET, Plenta KJ, Taichman NS, McCauley LK. Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. Cancer Res 2002;62:1832-1837
-
(2002)
Cancer Res
, vol.62
, pp. 1832-1837
-
-
Taichman, R.S.1
Cooper, C.2
Keller, E.T.3
Plenta, K.J.4
Taichman, N.S.5
McCauley, L.K.6
-
29
-
-
34748820033
-
Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response
-
Koizumi K, Hojo S, Akashi T, Yasumoto K, Saiki I. Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response. Cancer Sci 2007;98:1652-1658
-
(2007)
Cancer Sci
, vol.98
, pp. 1652-1658
-
-
Koizumi, K.1
Hojo, S.2
Akashi, T.3
Yasumoto, K.4
Saiki, I.5
-
30
-
-
34547663507
-
Cell motility and cytoskeletal regulation in invasion and metastasis
-
Kedrin D, van Rheenen J, Hernandez L, Condeells J, Segall J. Cell motility and cytoskeletal regulation in invasion and metastasis. J Mammary Gland Biol Neoplasia 2007;12:143-152
-
(2007)
J Mammary Gland Biol Neoplasia
, vol.12
, pp. 143-152
-
-
Kedrin, D.1
Van Rheenen, J.2
Hernandez, L.3
Condeells, J.4
Segall, J.5
-
31
-
-
4944229701
-
A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors
-
Wyckoff J, Wang W, Lin EY, et al. A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res 2004;64:7022-7029
-
(2004)
Cancer Res
, vol.64
, pp. 7022-7029
-
-
Wyckoff, J.1
Wang, W.2
Lin, E.Y.3
-
32
-
-
20444436815
-
Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/ epidermal growth factor paracrine loop
-
Goswami S, Sahai E, Wyckoff JB, et al. Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/ epidermal growth factor paracrine loop. Cancer Res 2005;65:5278-5283
-
(2005)
Cancer Res
, vol.65
, pp. 5278-5283
-
-
Goswami, S.1
Sahai, E.2
Wyckoff, J.B.3
-
33
-
-
0037428875
-
Co-cultivation of pancreatic cancer cells with orthotopic tumor-derived fibroblasts: Fibroblasts stimulate tumor cell invasion via HGF secretion whereas cancer cells exert a minor regulative effect on fibroblasts HGF production
-
Qian LW, Mizumoto K, Maehara N, et al. Co-cultivation of pancreatic cancer cells with orthotopic tumor-derived fibroblasts: fibroblasts stimulate tumor cell invasion via HGF secretion whereas cancer cells exert a minor regulative effect on fibroblasts HGF production. Cancer Lett 2003;190:105-112
-
(2003)
Cancer Lett
, vol.190
, pp. 105-112
-
-
Qian, L.W.1
Mizumoto, K.2
Maehara, N.3
-
34
-
-
0037115647
-
Expression of CXC chemokine receptor-4 enhances the pulmonary metastatic potential of murine B16 melanoma cells
-
Murakami T, Maki W, Cardones AR, et al. Expression of CXC chemokine receptor-4 enhances the pulmonary metastatic potential of murine B16 melanoma cells. Cancer Res 2002;62:7328-7334
-
(2002)
Cancer Res
, vol.62
, pp. 7328-7334
-
-
Murakami, T.1
Maki, W.2
Cardones, A.R.3
-
35
-
-
19944433608
-
Skeletal localization and neutralization of the SDF-1 (CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo
-
Sun YX, Schneider A, Jung Y, et al. Skeletal localization and neutralization of the SDF-1 (CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo. J Bone Miner Res 2005;20:318-329
-
(2005)
J Bone Miner Res
, vol.20
, pp. 318-329
-
-
Sun, Y.X.1
Schneider, A.2
Jung, Y.3
|