The low-temperature inflection observed in neutron scattering measurements of proteins is due to methyl rotation: Direct evidence using isotope labeling and molecular dynamics simulations

Journal of the American Chemical Society

Volumn 132, Issue 14, 2010, Pages 4990-4991

  Wood, Kathleen ^a,b   Tobias, Douglas J ^c   Kessler, Brigitte ^d   Gabel, Frank ^e,f,g   Oesterhelt, Dieter ^c   Mulder, Frans A A ^h   Zaccai, Giuseppe ^a   Weik, Martin ^e,f,g  

^a INSTITUT LAUE LANGEVIN   (France)

^b AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^e CEA GRENOBLE   (France)

^f CNRS   (France)

^g UNIV GRENOBLE ALPES   (France)

^h UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CORRELATION TIME; EXPERIMENTAL DATA; EXPERIMENTAL EVIDENCE; HIGH-RESOLUTION SPECTROMETER; INSTRUMENTAL RESOLUTION; ISOTOPE LABELING; LOW TEMPERATURES; MEAN SQUARE DISPLACEMENT; METHYL GROUP; METHYL GROUP ROTATION; METHYL ROTATION; MOLECULAR DYNAMICS SIMULATIONS; NATIVE PROTEINS; NEUTRON SCATTERING EXPERIMENTS; NEUTRON SCATTERING MEASUREMENTS; PURPLE MEMBRANES; SIDE-CHAIN; SOLID STATE NMR;

HYDROCARBONS; ISOTOPES; LABELING; MOLECULAR DYNAMICS; NEUTRON DIFFRACTION; NEUTRON SCATTERING; NEUTRONS; PROTEINS; SPECTROMETERS; SPECTROMETRY;

ROTATION;

AMINO ACID; BACTERIORHODOPSIN; DEUTERIUM; HYDROGEN; LYSINE; MEMBRANE PROTEIN;

ARTICLE; ISOTOPE LABELING; LOW TEMPERATURE PROCEDURES; MACROMOLECULE; MOLECULAR DYNAMICS; NEUTRON SCATTERING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN ANALYSIS; SPECTROMETER;

BACTERIORHODOPSINS; ISOTOPE LABELING; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DYNAMICS SIMULATION; NEUTRON DIFFRACTION; ROTATION; TEMPERATURE;

EID: 77950805313     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja910502g     Document Type: Article

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