Antiproliferative activities of methanolic extracts from a neotropical ganoderma species (Aphyllophoromycetideae): Identification and characterization of a novel ganoderic acid

International Journal of Medicinal Mushrooms

Volumn 12, Issue 1, 2010, Pages 17-31

  Welti, Stephane ^a   Moreau, Pierre Arthur ^a   Azaroual, Nathalie ^b   Lemoine, Amelie ^c   Duhal, Nathalie ^a   Kouach, Mostafa ^a,c   Millet, Régis ^c   Courtecuisse, Régis ^a  

^a UNIV LILLE   (France)

^b CNRS   (France)

^c Faculté des Sciences Pharmaceutiques et Biologiques Université de Lille   (France)

Author keywords

Caribbean species; Ganoderic acid FWI; Ganoderma lucidum; Ganoderma tuberculosum; Ganodermataceae; HT29; Lingzhi mushroom; MCF 7; Medicinal mushrooms; PC 3

Indexed keywords

GANODERIC ACID; GANODERMA AUSTRALE EXTRACT; GANODERMA GIBBOSUM EXTRACT; GANODERMA LUCIDUM EXTRACT; GANODERMA PERZONATUM EXTRACT; GANODERMA TROPICUM EXTRACT; GANODERMA TUBERCULOSUM EXTRACT; HUMPHREYA COFFEATA EXTRACT; METHANOL; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; TRITERPENOID; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL; CANCER GRADING; CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; COLON ADENOCARCINOMA; DRUG ACTIVITY; DRUG ANALYSIS; DRUG IDENTIFICATION; DRUG INHIBITION; DRUG ISOLATION; DRUG STRUCTURE; GANODERMA; GANODERMA AUSTRALE; GANODERMA GIBBOSUM; GANODERMA LUCIDUM; GANODERMA PERZONATUM; GANODERMA TROPICUM; GANODERMA TUBERCULOSUM; HUMAN; HUMAN CELL; HUMPHREYA COFFEATA; PROSTATE CANCER; TRADITIONAL MEDICINE;

BASIDIOMYCOTA; GANODERMA; GANODERMA LUCIDUM; GANODERMA TUBERCULOSUM; GANODERMATACEAE;

EID: 77950795908     PISSN: 15219437     EISSN: None     Source Type: Journal    
DOI: 10.1615/IntJMedMushr.v12.i1.20     Document Type: Article

References (36)

1. Wasser SP. Reishi or Ling Zhi (Ganoderma lucidum). Encyclopedia of Dietary Supplements. Coates PM, Blackman MR, Cragg GM, Levine M, Moss J, White JD, editors. New York: Marcel Dekker; 2005. p. 603-21.
2. Chinese Pharmacopoeia Commission, editor. Pharmacopoeia of the People-s Republic of China. Vol. 1. Beijing (China): Chemical Industry Press; 2000; p. 130.
3. Paterson RR. Ganoderma-a therapeutic fungal biofactory. Phytochemistry. 2006;67:1985-2001.
4. Toth JO, Luu B, Ourisson G. Les acides ganodériques T á Z: tritàrpenes cytotoxiques de Ganoderma lucidum. Tetrahedron Lett. 1983;24:1081-4.
5. Lee S, Park S, Oh JJ, Yang C. Natural inhibitors for protein prenyltransferase. Planta Med. 1998;64:303-8. (Pubitemid 28234264)
6. Min BS, Gao JJ, Nakamura N, Hattori M. Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against Meth-A and LLC tumor cells. Chem Pharm Bull. 2000;48:1026-33. (Pubitemid 30485402)
7. Wu TS, Shi LS, Kuo SC. Cytotoxicity of Ganoderma lucidum triterpenes. J Nat Prod. 2001;64:1121-2.
8. Gao JJ, Min BS, Ahn EM, Norio N, Lee HK, Hattori M. New triterpene aldehydes, lucialdéhydes A-C, (Pubitemid 41694906)
9. Liu J, Shimizu K, Konishi F, Kumamoto S, Kondo R. The antiandrogen effect of Ganoderol B isolated from the fruiting body of Ganoderma lucidum. Bioorg Med Chem. 2007;15:4966-72. (Pubitemid 46836827)
10. Moncalvo JM, Ryvarden L. Synopsis fungorum, volume 11: A nomenclature study of the Ganodermataceae Donk. Devon (UK): NHBS Environment Bookstore; 1997. 114
11. Ryvarden L. Synopsis fungorum, volume 5: genera of polypores, nomenclature and taxonomy. Devon (UK): NHBS Environment Bookstore; 1991. 363 p.
12. Steyaert RL. Study of some Ganoderma species. Bull Jard Bot Nat Belg. 1980;50:135-86.
13. Moncalvo JM, Wang HF, Hseu RSH. Gene phylogeny of the Ganoderma lucidum complex based on ribosomal DNA sequences. Comparison with traditional taxonomic characters. Mycol Res. 1995;99:1489-99.
14. Welti S, Courtecuisse C, Decock C. The Ganoderma - taceae in the French West Indies (Guadeloupe and Martinique). Fungal Biodivers. Submitted 2009. 15. Jiang J, Grieb B, Thyagarajan A, Sliva D. Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF--B signaling. Int J Mol Med. 2008;21:577-84.
15. Liu J, Shiono J, Shimizu K, Kukita A, Kukita T, Kondo R. Ganoderic acid DM: anti-androgenic osteoclastogenesis inhibitor. Bioorg Med Chem. 2009;19:2154-7.
16. Ryvarden L. Synopsis fungorum, volume 19: Neotropical polypores part 1. Introduction, Hymenochaetaceae and Ganodermataceae. Devon (UK): NHBS Environment Bookstore; 2004; 228 p.
17. Gardes M, Bruns TD. ITS primers with enhanced specifi -city for Basidiomycetes-application to the identifi cation of ycorrhizae and rusts. Mol Ecol. 1993;2:113-8.
18. Chen Y, Yan Y, Xie MY, Nie SP, Liu W, Gong XF, Wang YX. Development of chromatographic fi ngerprint for the chloroform extracts of Ganoderma lucidum by HPLC and LC-MS. J Pharm Biomed Anal. 2008;47:469-77.
19. Yang M, Wang X, Guan S, Xia J, Sun J, Guo H, Guo DA. Analysis of triterpenoids in Ganoderma lucidum using liquid chromatography coupled with electrospray ionization mass spectrometry. J Am Soc Mass Spectrom. 2007;18:927-39. (Pubitemid 46617282)
20. Fu CM, Lu GH, Schmitz OJ, Li ZW, Leung KSY. Improved chromatographic fi ngerprints for facile differentiation of two Ganoderma spp. Biomed Chromatogr. 2008;23:280-8.
21. Kikuchi T, Matsuda S, Kadota S, Murai Y, Ogita Z. Ganoderic acid D, E, F, and H and lucidenic acid D,E, and F, new riterpenoids from Ganoderma lucidum. Chem Pharm Bull. 1985;33:2624-7.
22. Hu H, Ahn NS, Yang X, Lee YS, Kang KS. Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF-7 human breast cancer cell. Int J Cancer. 2002;102:250-3. (Pubitemid 35222292)
23. Lu QY, Jin YS, Zhang Q, Zhang Z, Heber D, Go VL, Li FP, Rao JY. Ganoderma lucidum extracts inhibit growth and induce actin polymerisation in bladder cancer cells in vitro. Cancer Lett. 2004;216:9-20. (Pubitemid 39410491)
24. Tomasi S, Lohézic-Le Déhévat F, Sauleau P, Bézivin C, Boustie J. Cytotoxic activity of methanol extracts from Basidiomycete mushrooms on murine cancer cell lines. Pharmazie. 2004;59:290-300.
25. Fujita R, Liu J, Shimizu K, Konishi F, Kiyoshi N, Kumamoto S, Ueda C, Tajiri H, Kanedo S, Suimi Y, (Pubitemid 41375944)
26. Zaidman BZ, Wasser SP, Nevo E, Mahajna J. Coprinus comatus and Ganoderma lucidum interfere with androgen receptor function in LNCaP prostate cancer cells. Mol Biol Rep. 2008;35:107-17.
27. Liu GQ, Ding CY, Wang XL. Mechanisms of anticancer action of triterpenoids from Ganoderma lucidum: a review of recent researches. Mycosystema. 2007;26:470-6.
28. Kim HW, Kim BK. Biomedicinal triterpenoids of Ganoderma lucidum (Curt.: Fr.) P. Karst. (Aphyllophoromycetideae). Int J Med Mushr. 1999;1:121-38.
29. Lapassat AV. Étude du Lingzhi (champignons merveilleux). Aspect littéraire et médical. Mémoire de ma-trise de langue et littérature chinoises. Institut d-études transtextuelles et transculturelles. Université de Lyon 3; 2000. p. 80.
30. Chen DH, Chen WKD. Determination of Ganoderic acids in triterpenoid constituents of Ganoderma tsugae. J Food Drug Anal. 2003;11:195-201.
31. Li CH, Chen PY, Chang UM, Kan LS, Fang WH, Tsai KS, Lin SB. Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells. Life Sci. 2005;77:252-65.
32. Wang XM, Yang M, Guan SH, Liu RX, Xia JM, Bi KS, Guo DA. Quantitative determination of six major triterpenoids in Ganoderma lucidum and related species by high performance liquid chromatography. J Pharm Biomed Anal. 2006;41:838-44.
33. Wang F, Liu JK. Highly oxygenated lanostane triterpenoids from the fungus Ganoderma applanatum. Chem Pharm Bull. 008;56:1035-7. (Pubitemid 351949730)
34. Su CH, Yang YZ, Ho HO, Hu CH, Sheu MT. Performance liquid chromatographic analysis for the characterization of triterpenoids from Ganoderma. J Chromatogr Sci. 2001;3:93-100.
35. Liu YW, Gao JL, Guan J, Qian ZM, Feng K, Li SP. Evaluation of antiproliferative activities and action mechanisms of extracts from two species of Ganoderma on tumor cell lines. J Agric Food Chem. 2009;57:3087-93.
36. Hsu SC, Ou CC, Li JW, Chuang TC, Kuo HP, Liu JY, Chen CS, Lin SC, Su CH, Kao MC. Ganoderma tsugae extracts inhibit colorectal cancer cell growth via G2/M cell cycle arrest. J thnopharmacol.2008;120:394-401.