Nociceptin and its metabolite attenuate U0126-induced memory impairment through a nociceptin opioid peptide (NOP) receptor-independent mechanism

Neurobiology of Learning and Memory

Volumn 93, Issue 3, 2010, Pages 396-405

  Miwa, Masaya ^a   Uchida, Shogo ^a   Horiba, Fumika ^a   Takeshima, Hiroshi ^b   Nabeshima, Toshitaka ^a   Hiramatsu, Masayuki ^a  

^a MEIJO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

ERK; Hippocampus; MEK inhibitor; Memory U0126; Nociceptin metabolite; Nociceptin orphanin FQ; NOP receptor; Protein kinase A; Rp cAMPS

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; MITOGEN ACTIVATED PROTEIN KINASE 1; NEUROPEPTIDE RECEPTOR; NOCICEPTIN; NOCICEPTIN DERIVATIVE; NOCICEPTIN OPIATE PEPTIDE RECEPTOR; NOCICEPTIN[1-13]; NOCICEPTIN[14-17]; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG METABOLISM; DRUG RECEPTOR BINDING; ELECTRIC SHOCK; ENZYME PHOSPHORYLATION; HIPPOCAMPUS; IN VIVO STUDY; KNOCKOUT MOUSE; MALE; MAZE TEST; MEMORY DISORDER; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; WORKING MEMORY;

ANIMALS; BUTADIENES; ENZYME INHIBITORS; HUMANS; MALE; MEMORY DISORDERS; MICE; NITRILES; OPIOID PEPTIDES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, OPIOID; VASODILATOR AGENTS;

EID: 77950689980     PISSN: 10747427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nlm.2009.12.006     Document Type: Article

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