-
1
-
-
84857062604
-
-
web site. Available at: Last accessed February 11
-
Report on the Global AIDS Epidemic 2008. UNAIDS web site. Available at: www.unaids.org/en/KnowledgeCentre/HIVData/GlobalReport/2008/2008-Global-report. asp. Last accessed February 11, 2010.
-
(2010)
Report on the Global AIDS Epidemic 2008
-
-
-
2
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV outpatient study investigators
-
Palella FJ Jr., Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med. 1998;338:853-860.
-
(1998)
N Engl J Med.
, vol.338
, pp. 853-860
-
-
Palella Jr., F.J.1
Delaney, K.M.2
Moorman, A.C.3
-
3
-
-
0038162585
-
Decline in the AIDS and death rates in the EuroSIDA study: An observational study
-
Mocroft A, Ledergerber B, Katlama C, et al. Decline in the AIDS and death rates in the EuroSIDA study: an observational study. Lancet. 2003;362:22-29.
-
(2003)
Lancet
, vol.362
, pp. 22-29
-
-
Mocroft, A.1
Ledergerber, B.2
Katlama, C.3
-
4
-
-
52749083531
-
British HIV Association guidelines for the treatment of HIV-1-infected adults with antiretroviral therapy 2008
-
Gazzard BG, Anderson J, Babiker A, et al. British HIV Association guidelines for the treatment of HIV-1-infected adults with antiretroviral therapy 2008. HIV Med. 2008;9:563-608.
-
(2008)
HIV Med.
, vol.9
, pp. 563-608
-
-
Gazzard, B.G.1
Anderson, J.2
Babiker, A.3
-
5
-
-
48949097660
-
Antiretroviral treatment of adult HIV infection 2008 recommendations of the International AIDS Society-USA panel
-
Hammer SM, Eron JJ Jr., Reiss P, et al. Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel. JAMA. 2008;300:555-570.
-
(2008)
JAMA.
, Issue.300
, pp. 555-570
-
-
Hammer, S.M.1
Eron Jr., J.J.2
Reiss, P.3
-
6
-
-
84855616052
-
-
Panel on Antiretroviral Guidelines for Adults and Adolescents, Department of Health and Human Services; December 1. Available at, Last accessed: February 11, 2010
-
Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services; December 1, 2009:1-161. Available at http://www.aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf. Last accessed: February 11, 2010.
-
(2009)
Guidelines for the Use of Antiretroviral Agents in HIV-1-infected Adults and Adolescents
, pp. 1-161
-
-
-
7
-
-
84868362475
-
Rapid advice: Antiretroviral therapy for HIV infection in adults and adolescents
-
November. Available at, Last accessed: February 11, 2010
-
Rapid advice: antiretroviral therapy for HIV infection in adults and adolescents. World Health Organization ART Guideline Review Committee; November 2009. Available at: www.who.int/hiv/pub/arv/rapid-advice-art.pdf. Last accessed: February 11, 2010.
-
(2009)
World Health Organization ART Guideline Review Committee
-
-
-
8
-
-
77950678870
-
-
Epzicom (package insert). Research Triangle Park, NC: GlaxoSmithKline; 2009
-
Epzicom (package insert). Research Triangle Park, NC: GlaxoSmithKline; 2009.
-
-
-
-
9
-
-
68949206285
-
-
HLA-B.*5701 screening prior to abacavir prescription: Clinical and laboratory aspects
-
Nolan D. HLA-B. *5701 screening prior to abacavir prescription: clinical and laboratory aspects. Crit Rev Clin Lab Sci. 2009;46:153-165.
-
(2009)
Crit Rev Clin Lab Sci.
, vol.46
, pp. 153-165
-
-
Nolan, D.1
-
10
-
-
42649130015
-
Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: A multi-cohort collaboration
-
Sabin CA, Worm SW, Weber R, et al. Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration. Lancet. 2008;371:1417-1426.
-
(2008)
Lancet
, vol.371
, pp. 1417-1426
-
-
Sabin, C.A.1
Worm, S.W.2
Weber, R.3
-
11
-
-
60649109560
-
Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients
-
Lundgren JD, Neuhaus J, Babiker A, et al. Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients. AIDS. 2008;22:F17-F24.
-
(2008)
AIDS
, vol.22
-
-
Lundgren, J.D.1
Neuhaus, J.2
Babiker, A.3
-
12
-
-
67649110188
-
Impact of specific NRTI and PI exposure on the risk of myocardial infarction: A case-control study nested within FHDH ANRS C04
-
Abstract: presented at. February 8-11; Montreal, Canada. Abstract: #43LB
-
Lang SM-KM, Cotte L, Gilquin L, et al. Impact of specific NRTI and PI exposure on the risk of myocardial infarction: a case-control study nested within FHDH ANRS C04. Abstract: presented at: 16th Conference on Retroviruses and Oppotunistic Infections. February 8-11, 2009; Montreal, Canada. Abstract: #43LB.
-
(2009)
16th Conference on Retroviruses and Oppotunistic Infections
-
-
Lang, S.M.-K.M.1
Cotte, L.2
Gilquin, L.3
-
13
-
-
73549088748
-
Abacavir and risk of myocardial infarction in HIV-infected patients on highly active antiretroviral therapy: A population-based nationwide cohort study
-
Obel N, Farkas D, Kronborg G, et al. Abacavir and risk of myocardial infarction in HIV-infected patients on highly active antiretroviral therapy: a population-based nationwide cohort study. HIV Med. 2010;11:130-136.
-
(2010)
HIV Med.
, vol.11
, pp. 130-136
-
-
Obel, N.1
Farkas, D.2
Kronborg, G.3
-
14
-
-
73349134686
-
Abacavirlamivudine versus tenofovir-emtricitabine for initial HIV-1 therapy
-
Sax PE, Tierney C, Collier AC, et al. Abacavirlamivudine versus tenofovir-emtricitabine for initial HIV-1 therapy. N Engl J Med. 2009;361:2230-2240.
-
(2009)
N Engl J Med.
, vol.361
, pp. 2230-2240
-
-
Sax, P.E.1
Tierney, C.2
Collier, A.C.3
-
15
-
-
12444280338
-
The bioequivalence and effect of food on a new oncea-day fixed-dose combination tablet of abacavir (ABC) and lamivudine (3TC)
-
Poster presented at, October 30 2004 - November 2, 2004; Washington, DC
-
Baker KL, Lou Y, Yuen G, Murray S, Stein D. The bioequivalence and effect of food on a new oncea-day fixed-dose combination tablet of abacavir (ABC) and lamivudine (3TC). Poster presented at: 44th Interscience Conference on Antimicrobial Agents and Chemotherapy. October 30, 2004 - November 2, 2004; Washington, DC.
-
44th Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Baker, K.L.1
Lou, Y.2
Yuen, G.3
Murray, S.4
Stein, D.5
-
16
-
-
0032766290
-
Abacavir: Absolute bioavailability, bioequivalence of three oral formulations, and effect of food
-
Chittick GE, Gillotin C, McDowell JA, et al. Abacavir: absolute bioavailability, bioequivalence of three oral formulations, and effect of food. Pharmacotherapy. 1999;19:932-942.
-
(1999)
Pharmacotherapy.
, vol.19
, pp. 932-942
-
-
Chittick, G.E.1
Gillotin, C.2
McDowell, J.A.3
-
18
-
-
77950657743
-
-
Ziagen (package insert). Research Park Triangle, NC: GlaxoSmithKline; 2009
-
Ziagen (package insert). Research Park Triangle, NC: GlaxoSmithKline; 2009.
-
-
-
-
19
-
-
33645391801
-
Impact of pregnancy on abacavir pharmacokinetics
-
Best BM, Mirochnick M, Capparelli EV, et al. Impact of pregnancy on abacavir pharmacokinetics. AIDS. 2006;20:553-560.
-
(2006)
AIDS
, vol.20
, pp. 553-560
-
-
Best, B.M.1
Mirochnick, M.2
Capparelli, E.V.3
-
20
-
-
0034872971
-
Pharmacokinetics of abacavir in HIV-1-infected patients with impaired renal function
-
Izzedine H, Launay-Vacher V, Aymard G, Legrand M, Deray G. Pharmacokinetics of abacavir in HIV-1-infected patients with impaired renal function. Nephron. 2001;89:62-67.
-
(2001)
Nephron.
, vol.89
, pp. 62-67
-
-
Izzedine, H.1
Launay-Vacher, V.2
Aymard, G.3
Legrand, M.4
Deray, G.5
-
22
-
-
65649133113
-
Steady-state pharmacokinetics of abacavir in plasma and intracellular carbovir triphosphate following administration of abacavir at 600 milligrams once daily and 300 milligrams twice daily in human immunodeficiency virus-infected subjects
-
Moyle G, Boffito M, Fletcher C, et al. Steady-state pharmacokinetics of abacavir in plasma and intracellular carbovir triphosphate following administration of abacavir at 600 milligrams once daily and 300 milligrams twice daily in human immunodeficiency virus-infected subjects. Antimicrob Agents Chemother. 2009;53:1532-1538.
-
(2009)
Antimicrob Agents Chemother.
, vol.53
, pp. 1532-1538
-
-
Moyle, G.1
Boffito, M.2
Fletcher, C.3
-
23
-
-
22344455482
-
Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens
-
Hawkins T, Veikley W, St. Claire RL 3rd, Guyer B, Clark N, Kearney BP. Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens. J Acquir Immune Defic Syndr. 2005;39:406-411.
-
(2005)
J Acquir Immune Defic Syndr.
, vol.39
, pp. 406-411
-
-
Hawkins, T.1
Veikley, W.2
St. Claire Iii., R.L.3
Guyer, B.4
Clark, N.5
Kearney, B.P.6
-
24
-
-
0037165904
-
Intracellular carbovir triphosphate levels in patients taking abacavir once a day
-
Harris M, Back D, Kewn S, Jutha S, Marina R, Montaner JS. Intracellular carbovir triphosphate levels in patients taking abacavir once a day. AIDS. 2002;16:1196-1197.
-
(2002)
AIDS
, vol.16
, pp. 1196-1197
-
-
Harris, M.1
Back, D.2
Kewn, S.3
Jutha, S.4
Marina, R.5
Montaner, J.S.6
-
25
-
-
3042723210
-
A study examining the pharmacokinetics of abacavir and the intracellular carbovir triphosphate (GSK Protocol CNA 10905)
-
Abstract: presented at, September, Chicago, IL, USA. Abstract: A-1797
-
Piliero P, Shachoy-Clark AD, Para M, et al. A study examining the pharmacokinetics of abacavir and the intracellular carbovir triphosphate (GSK Protocol CNA 10905). Abstract: presented at: 43rd International Conference on Antimicrobial Agents and Chemotherapy. September 14-17, 2003; Chicago, IL, USA. Abstract: A-1797.
-
(2003)
43rd International Conference on Antimicrobial Agents and Chemotherapy
, pp. 14-17
-
-
Piliero, P.1
Shachoy-Clark, A.D.2
Para, M.3
-
26
-
-
0033929197
-
Population pharmacokinetics and pharmacodynamic modeling of abacavir (1592U89) from a dose-ranging, double-blind, randomized monotherapy trial with human immunodeficiency virus-infected subjects
-
Weller S, Radomski KM, Lou Y, Stein DS. Population pharmacokinetics and pharmacodynamic modeling of abacavir (1592U89) from a dose-ranging, double-blind, randomized monotherapy trial with human immunodeficiency virus-infected subjects. Antimicrob Agents Chemother. 2000;44:2052-2060.
-
(2000)
Antimicrob Agents Chemother.
, vol.44
, pp. 2052-2060
-
-
Weller, S.1
Radomski, K.M.2
Lou, Y.3
Stein, D.S.4
-
27
-
-
15044341385
-
Abacavir once or twice daily combined with once-daily lamivudine and efavirenz for the treatment of antiretroviralnaive HIV-infected adults: Results of the Ziagen Once Daily in Antiretroviral Combination Study
-
Moyle GJ, DeJesus E, Cahn P, et al. Abacavir once or twice daily combined with once-daily lamivudine and efavirenz for the treatment of antiretroviralnaive HIV-infected adults: results of the Ziagen Once Daily in Antiretroviral Combination Study. J Acquir Immune Defic Syndr. 2005;38:417-425.
-
(2005)
J Acquir Immune Defic Syndr.
, vol.38
, pp. 417-425
-
-
Moyle, G.J.1
Dejesus, E.2
Cahn, P.3
-
28
-
-
84868347044
-
Viral dynamics and pharmacokinetics in vivo of tenofovir disoproxil fumarate and abacavir: Evidence of a non-additive antiviral effect
-
Goicoechea M,Jain S, Kemper C., et al editors, Poster presented at, February 8-11; Montréal, Canada. Poster no. 703.Available at
-
Goicoechea M, Jain S, Kemper C, et al., editors. Viral Dynamics and Pharmacokinetics in vivo of Tenofovir Disoproxil Fumarate and Abacavir: Evidence of a Non-additive Antiviral Effect. Poster presented at: 16th Conference on Retroviruses and Opportunistic Infections. February 8-11, 2009; Montréal, Canada. Poster no. 703.Available at: www.hivandhepatitis.com/2009icr/croi/pdf/ 3Golcoechea.pdf.
-
(2009)
16th Conference on Retroviruses and Opportunistic Infections
-
-
-
29
-
-
0033914965
-
Multiple-dose pharmacokinetics and pharmacodynamics of abacavir alone and in combination with zidovudine in human immunodeficiency virus-infected adults
-
McDowell JA, Lou Y, Symonds WS, Stein DS. Multiple-dose pharmacokinetics and pharmacodynamics of abacavir alone and in combination with zidovudine in human immunodeficiency virus-infected adults. Antimicrob Agents Chemother. 2000;44:2061-2067.
-
(2000)
Antimicrob Agents Chemother.
, vol.44
, pp. 2061-2067
-
-
McDowell, J.A.1
Lou, Y.2
Symonds, W.S.3
Stein, D.S.4
-
30
-
-
34547224761
-
Evolving simplified treatment strategies for HIV infection: The role of a single-class quadruple-nucleoside/nucleotide regimen of trizivir and tenofovir
-
Mastroianni CM, d'Ettorre G, Vullo V. Evolving simplified treatment strategies for HIV infection: the role of a single-class quadruple-nucleoside/ nucleotide regimen of trizivir and tenofovir. Expert Opin Pharmacother. 2006;7:2233-2241.
-
(2006)
Expert Opin Pharmacother.
, vol.7
, pp. 2233-2241
-
-
Mastroianni, C.M.1
D'ettorre, G.2
Vullo, V.3
-
31
-
-
0037764105
-
Indinavir, efavirenz, and abacavir pharmacokinetics in human immunodeficiency virus-infected subjects
-
DiCenzo R, Forrest A, Squires KE, et al. Indinavir, efavirenz, and abacavir pharmacokinetics in human immunodeficiency virus-infected subjects. Antimicrob Agents Chemother. 2003;47:1929-1935.
-
(2003)
Antimicrob Agents Chemother.
, vol.47
, pp. 1929-1935
-
-
Dicenzo, R.1
Forrest, A.2
Squires, K.E.3
-
32
-
-
34547768666
-
Abacavir plasma pharmacokinetics in the absence and presence of atazanavir/ritonavir or lopinavir/ritonavir and vice versa in HIV-infected patients
-
Waters L, Moyle G, D'Avolio A, et al., editors
-
Waters L, Moyle G, D'Avolio A, et al., editors. Abacavir plasma pharmacokinetics in the absence and presence of atazanavir/ritonavir or lopinavir/ritonavir and vice versa in HIV-infected patients. Antivir Ther. 2007;12:825-1380
-
(2007)
Antivir Ther.
, vol.12
, pp. 825-1380
-
-
-
33
-
-
77950631644
-
-
Aptivus (package insert). Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc; 2009
-
Aptivus (package insert). Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc; 2009.
-
-
-
-
34
-
-
0034045094
-
Pharmacokinetic interaction of abacavir (1592U89) and ethanol in human immunodeficiency virus-infected adults
-
McDowell JA, Chittick GE, Stevens CP, Edwards KD, Stein DS. Pharmacokinetic interaction of abacavir (1592U89) and ethanol in human immunodeficiency virus-infected adults. Antimicrob Agents Chemother. 2000;44:1686-1690.
-
(2000)
Antimicrob Agents Chemother.
, vol.44
, pp. 1686-1690
-
-
McDowell, J.A.1
Chittick, G.E.2
Stevens, C.P.3
Edwards, K.D.4
Stein, D.S.5
-
35
-
-
34247624140
-
Early virologic failure in HIV-coinfected hepatitis C patients treated with the peginterferon-ribavirin combination does abacavir play a role?
-
Bani-Sadr F, Denoeud L, Morand P, et al. Early virologic failure in HIV-coinfected hepatitis C patients treated with the peginterferon-ribavirin combination: does abacavir play a role? J Acquir Immune Defic Syndr. 2007;45:123-125.
-
(2007)
J Acquir Immune Defic Syndr.
, vol.45
, pp. 123-125
-
-
Bani-Sadr, F.1
Denoeud, L.2
Morand, P.3
-
36
-
-
0029591139
-
Pharmacokinetics, absolute bioavailability, and absorption characteristics of lamivudine
-
Yuen GJ, Morris DM, Mydlow PK, Haidar S, Hall ST, Hussey EK. Pharmacokinetics, absolute bioavailability, and absorption characteristics of lamivudine. J Clin Pharmacol. 1995;35:1174-1180.
-
(1995)
J Clin Pharmacol.
, vol.35
, pp. 1174-1180
-
-
Yuen, G.J.1
Morris, D.M.2
Mydlow, P.K.3
Haidar, S.4
Hall, S.T.5
Hussey, E.K.6
-
37
-
-
77950653520
-
-
Epivir (package insert). Research Triangle Park, NC: GlaxoSmithKline; 2009
-
Epivir (package insert). Research Triangle Park, NC: GlaxoSmithKline; 2009.
-
-
-
-
38
-
-
0032906981
-
Clinical pharmacokinetics of lamivudine
-
Johnson MA, Moore KH, Yuen GJ, Bye A, Pakes GE. Clinical pharmacokinetics of lamivudine. Clin Pharmacokinet. 1999;36:41-66.
-
(1999)
Clin Pharmacokinet.
, vol.36
, pp. 41-66
-
-
Johnson, M.A.1
Moore, K.H.2
Yuen, G.J.3
Bye, A.4
Pakes, G.E.5
-
39
-
-
0031723646
-
Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring
-
Moodley J, Moodley D, Pillay K, et al. Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring. J Infect Dis. 1998;178:1327-1333.
-
(1998)
J Infect Dis.
, vol.178
, pp. 1327-1333
-
-
Moodley, J.1
Moodley, D.2
Pillay, K.3
-
40
-
-
0029952016
-
Pharmacokinetics of lamivudine in human immunodeficiency virus-infected patients with renal dysfunction
-
Heald AE, Hsyu PH, Yuen GJ, Robinson P, Mydlow P, Bartlett JA. Pharmacokinetics of lamivudine in human immunodeficiency virus-infected patients with renal dysfunction. Antimicrob Agents Chemother. 1996;40:1514-1519.
-
(1996)
Antimicrob Agents Chemother.
, vol.40
, pp. 1514-1519
-
-
Heald, A.E.1
Hsyu, P.H.2
Yuen, G.J.3
Robinson, P.4
Mydlow, P.5
Bartlett, J.A.6
-
41
-
-
0031818475
-
The pharmacokinetics of lamivudine in patients with impaired hepatic function
-
Johnson MA, Horak J, Breuel P. The pharmacokinetics of lamivudine in patients with impaired hepatic function. Eur J Clin Pharmacol. 1998;54:363-366.
-
(1998)
Eur J Clin Pharmacol.
, vol.54
, pp. 363-366
-
-
Johnson, M.A.1
Horak, J.2
Breuel, P.3
-
42
-
-
0029900659
-
Pharmacokinetics of lamivudine administered alone and with trimethoprim-sulfamethoxazole
-
Moore KH, Yuen GJ, Raasch RH, et al. Pharmacokinetics of lamivudine administered alone and with trimethoprim-sulfamethoxazole. Clin Pharmacol Ther. 1996;59:550-558.
-
(1996)
Clin Pharmacol Ther.
, vol.59
, pp. 550-558
-
-
Moore, K.H.1
Yuen, G.J.2
Raasch, R.H.3
-
43
-
-
0001024860
-
The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1
-
Moore KH, Barrett JE, Shaw S, et al. The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1. AIDS. 1999;13:2239-2250.
-
(1999)
AIDS
, vol.13
, pp. 2239-2250
-
-
Moore, K.H.1
Barrett, J.E.2
Shaw, S.3
-
44
-
-
0034793648
-
Comparison of the plasma pharmacokinetics of lamivudine during twice and once daily administration in patients with HIV
-
Bruno R, Regazzi MB, Ciappina V, et al. Comparison of the plasma pharmacokinetics of lamivudine during twice and once daily administration in patients with HIV. Clin Pharmacokinet. 2001; 40:695-700.
-
(2001)
Clin Pharmacokinet
, vol.40
, pp. 695-700
-
-
Bruno, R.1
Regazzi, M.B.2
Ciappina, V.3
-
45
-
-
0347992034
-
Equivalent steady-state pharmacokinetics of lamivudine in plasma and lamivudine triphosphate within cells following administration of lamivudine at 300 milligrams once daily and 150 milligrams twice daily
-
Yuen GJ, Lou Y, Bumgarner NF, et al. Equivalent steady-state pharmacokinetics of lamivudine in plasma and lamivudine triphosphate within cells following administration of lamivudine at 300 milligrams once daily and 150 milligrams twice daily. Antimicrob Agents Chemother. 2004;48:176-182.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 176-182
-
-
Yuen, G.J.1
Lou, Y.2
Bumgarner, N.F.3
-
46
-
-
3943101413
-
Once-daily versus twice-daily lamivudine, in combination with zidovudine and efavirenz, for the treatment of antiretroviral-naive adults with HIV infection: A randomized equivalence trial
-
DeJesus E, McCarty D, Farthing CF, et al. Once-daily versus twice-daily lamivudine, in combination with zidovudine and efavirenz, for the treatment of antiretroviral-naive adults with HIV infection: a randomized equivalence trial. Clin Infect Dis. 2004;39:411-418.
-
(2004)
Clin Infect Dis.
, vol.39
, pp. 411-418
-
-
Dejesus, E.1
McCarty, D.2
Farthing, C.F.3
-
47
-
-
66149147423
-
Pilot pharmacokinetic study of human immunodeficiency virus-infected patients receiving tenofovir disoproxil fumarate (TDF): Investigation of systemic and intracellular interactions between TDF and abacavir, lamivudine, or lopinavir-ritonavir
-
Pruvost A, Negredo E, Theodoro F, et al. Pilot pharmacokinetic study of human immunodeficiency virus-infected patients receiving tenofovir disoproxil fumarate (TDF): investigation of systemic and intracellular interactions between TDF and abacavir, lamivudine, or lopinavir-ritonavir. Antimicrob Agents Chemother. 2009;53:1937-1943.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 1937-1943
-
-
Pruvost, A.1
Negredo, E.2
Theodoro, F.3
-
48
-
-
0035126997
-
Abacavir/lamivudine/zidovudine as a combined formulation tablet: Bioequivalence compared with each component administered concurrently and the effect of food on absorption
-
Yuen GJ, Lou Y, Thompson NF, et al. Abacavir/lamivudine/zidovudine as a combined formulation tablet: bioequivalence compared with each component administered concurrently and the effect of food on absorption. J Clin Pharmacol. 2001;41:277-288.
-
(2001)
J Clin Pharmacol.
, vol.41
, pp. 277-288
-
-
Yuen, G.J.1
Lou, Y.2
Thompson, N.F.3
-
49
-
-
25844464986
-
Effect of ribavirin on intracellular and plasma pharmacokinetics of nucleoside reverse transcriptase inhibitors in patients with human immunodeficiency virus-hepatitis C virus coinfection: Results of a randomized clinical study
-
Rodriguez-Torres M, Torriani FJ, Soriano V, et al. Effect of ribavirin on intracellular and plasma pharmacokinetics of nucleoside reverse transcriptase inhibitors in patients with human immunodeficiency virus-hepatitis C virus coinfection: results of a randomized clinical study. Antimicrob Agents Chemother. 2005;49:3997-4008.
-
(2005)
Antimicrob Agents Chemother.
, vol.49
, pp. 3997-4008
-
-
Rodriguez-Torres, M.1
Torriani, F.J.2
Soriano, V.3
-
50
-
-
40149097939
-
Shortterm safety and tolerability of a once-daily fixeddose abacavir-lamivudine combination versus twice-daily dosing of abacavir and lamivudine as separate components: Findings from the ALOHA study
-
Cohen CJ, Kubota M, Brachman PS, et al. Shortterm safety and tolerability of a once-daily fixeddose abacavir-lamivudine combination versus twice-daily dosing of abacavir and lamivudine as separate components: findings from the ALOHA study. Pharmacotherapy. 2008;28:314-322.
-
(2008)
Pharmacotherapy
, vol.28
, pp. 314-322
-
-
Cohen, C.J.1
Kubota, M.2
Brachman, P.S.3
-
51
-
-
21744446593
-
Once-daily abacavir in place of twice-daily administration
-
Goedken AM, Herman RA. Once-daily abacavir in place of twice-daily administration. Ann Pharmacother. 2005;39:1302-1308.
-
(2005)
Ann Pharmacother
, vol.39
, pp. 1302-1308
-
-
Goedken, A.M.1
Herman, R.A.2
-
52
-
-
67651056237
-
A simplification trial switching from nucleoside reverse transcriptase inhibitors to once-daily fixed-dose abacavir/lamivudine or tenofovir/ emtricitabine in HIV-1-infected patients with virological suppression
-
Martinez E, Arranz JA, Podzamczer D, et al. A simplification trial switching from nucleoside reverse transcriptase inhibitors to once-daily fixed-dose abacavir/lamivudine or tenofovir/emtricitabine in HIV-1-infected patients with virological suppression. J Acquir Immune Defic Syndr. 2009;51:290-297.
-
(2009)
J Acquir Immune Defic Syndr.
, vol.51
, pp. 290-297
-
-
Martinez, E.1
Arranz, J.A.2
Podzamczer, D.3
-
53
-
-
68649086238
-
Randomized, double-blind, placebo-matched, multicenter trial of abacavir/lamivudine or tenofovir/emtricitabine with lopinavir/ritonavir for initial HIV treatment
-
Smith KY, Patel P, Fine D, et al. Randomized, double-blind, placebo-matched, multicenter trial of abacavir/lamivudine or tenofovir/emtricitabine with lopinavir/ritonavir for initial HIV treatment. AIDS. 2009;23:1547-1556.
-
(2009)
AIDS
, vol.23
, pp. 1547-1556
-
-
Smith, K.Y.1
Patel, P.2
Fine, D.3
-
54
-
-
27944438845
-
Abacavir and lamivudine fixed-dose combination tablet once daily compared with abacavir and lamivudine twice daily in HIV-infected patients over 48 weeks (ESS30008, SEAL)
-
Sosa N, Hill-Zabala C, Dejesus E, et al. Abacavir and lamivudine fixed-dose combination tablet once daily compared with abacavir and lamivudine twice daily in HIV-infected patients over 48 weeks (ESS30008, SEAL). J Acquir Immune Defic Syndr. 2005;40:422-427.
-
(2005)
J Acquir Immune Defic Syndr.
, vol.40
, pp. 422-427
-
-
Sosa, N.1
Hill-Zabala, C.2
Dejesus, E.3
-
55
-
-
32644472009
-
Once daily administration of abacavir is not a clinical risk factor for suspected hypersensitivity reactions in clinical trials and rash is not sufficient to diagnose the reaction
-
Poster presented at, Boston, USA. February 23. Poster 836
-
Brothers CCA, Zhao H, Edwards M, Fleming J, Scott T. Once daily administration of abacavir is not a clinical risk factor for suspected hypersensitivity reactions in clinical trials and rash is not sufficient to diagnose the reaction. Poster presented at: 12th Conference on Retroviruses and Opportunistic Infections, Boston, USA. February 23, 2005. Poster 836.
-
(2005)
12th Conference on Retroviruses and Opportunistic Infections
-
-
Brothers, C.C.A.1
Zhao, H.2
Edwards, M.3
Fleming, J.4
Scott, T.5
-
56
-
-
0037006623
-
Association between presence of HLA-B*5701 HLA-DR7 and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
-
Mallal S, Nolan D, Witt C, et al. Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet. 2002;359:727-732.
-
(2002)
Lancet
, vol.359
, pp. 727-732
-
-
Mallal, S.1
Nolan, D.2
Witt, C.3
-
57
-
-
0037197044
-
Genetic variations in HLA-B region and hypersensitivity reactions to abacavir
-
Hetherington S, Hughes AR, Mosteller M, et al. Genetic variations in HLA-B region and hypersensitivity reactions to abacavir. Lancet. 2002;359:1121-1122.
-
(2002)
Lancet
, vol.359
, pp. 1121-1122
-
-
Hetherington, S.1
Hughes, A.R.2
Mosteller, M.3
-
58
-
-
38949196447
-
HLAB* 5701 screening for hypersensitivity to abacavir
-
Mallal S, Phillips E, Carosi G, et al. HLAB* 5701 screening for hypersensitivity to abacavir. N Engl J Med. 2008;358:568-579.
-
(2008)
N Engl J Med.
, vol.358
, pp. 568-579
-
-
Mallal, S.1
Phillips, E.2
Carosi, G.3
-
59
-
-
75649093029
-
Risk of myocardial infarction in patients with HIV infection exposed to specific individual antiretroviral drugs from the 3 major drug classes: The data collection on adverse events of anti-hiv drugs (D:A:D) study
-
Worm SW, Sabin C, Weber R, et al. Risk of myocardial infarction in patients with HIV infection exposed to specific individual antiretroviral drugs from the 3 major drug classes: the data collection on adverse events of anti-hiv drugs (D:A:D) study. J Infect Dis. 2010;201:318-330.
-
(2010)
J Infect Dis.
, vol.201
, pp. 318-330
-
-
Worm, S.W.1
Sabin, C.2
Weber, R.3
-
60
-
-
70349213594
-
Efficacy and safety of atazanavir-ritonavir plus abacavirlamivudine or tenofovir-emtricitabine in patients with hyperlipidaemia switched from a stable protease inhibitor-based regimen including one thymidine analogue
-
Calza L, Manfredi R, Colangeli V, et al. Efficacy and safety of atazanavir-ritonavir plus abacavirlamivudine or tenofovir-emtricitabine in patients with hyperlipidaemia switched from a stable protease inhibitor-based regimen including one thymidine analogue. AIDS Patient Care STDS. 2009;23:691-697.
-
(2009)
AIDS Patient Care STDS.
, vol.23
, pp. 691-697
-
-
Calza, L.1
Manfredi, R.2
Colangeli, V.3
-
61
-
-
33645988818
-
A prospective, 96-week study of the impact of Trizivir, Combivir/nelfinavir, and lamivudine/ stavudine/nelfinavir on lipids, metabolic parameters and efficacy in antiretroviral-naive patients: Effect of sex and ethnicity
-
Kumar PN, Rodriguez-French A, Thompson MA, et al. A prospective, 96-week study of the impact of Trizivir, Combivir/nelfinavir, and lamivudine/ stavudine/nelfinavir on lipids, metabolic parameters and efficacy in antiretroviral-naive patients: effect of sex and ethnicity. HIV Med. 2006;7:85-98.
-
(2006)
HIV Med.
, vol.7
, pp. 85-98
-
-
Kumar, P.N.1
Rodriguez-French, A.2
Thompson, M.A.3
-
62
-
-
34247144465
-
Metabolic effects of protease inhibitor-sparing antiretroviral regimens given as initial treatment of HIV-1 Infection (AIDS Clinical Trials Group Study A5095)
-
Shikuma CM, Yang Y, Glesby MJ, et al. Metabolic effects of protease inhibitor-sparing antiretroviral regimens given as initial treatment of HIV-1 Infection (AIDS Clinical Trials Group Study A5095). J Acquir Immune Defic Syndr. 2007;44:540-550.
-
(2007)
J Acquir Immune Defic Syndr.
, vol.44
, pp. 540-550
-
-
Shikuma, C.M.1
Yang, Y.2
Glesby, M.J.3
-
63
-
-
67651167085
-
Risk of myocardial infarction and abacavir therapy: No increased risk across 52 GlaxoSmithKlinesponsored clinical trials in adult subjects
-
Brothers CH, Hernandez JE, Cutrell AG, et al. Risk of myocardial infarction and abacavir therapy: no increased risk across 52 GlaxoSmithKlinesponsored clinical trials in adult subjects. J Acquir Immune Defic Syndr. 2009;51:20-28.
-
(2009)
J Acquir Immune Defic Syndr.
, vol.51
, pp. 20-28
-
-
Brothers, C.H.1
Hernandez, J.E.2
Cutrell, A.G.3
-
64
-
-
67649120904
-
No association of abacavir use with risk of myocardial infarction or severe cardiovascular disease events: Results from ACTG A5001
-
Abstract: presented at. February 8-11; Montreal, Canada. Abstract: #
-
Benson CRH, Zheng E, Koletar S, et al. No association of abacavir use with risk of myocardial infarction or severe cardiovascular disease events: results from ACTG A5001. Abstract: presented at: 16th Conference on Retroviruses and Opportunistic Infections. February 8-11, 2009; Montreal, Canada. Abstract: #721.
-
(2009)
16th Conference on Retroviruses and Opportunistic Infections
, pp. 721
-
-
Benson, C.R.H.1
Zheng, E.2
Koletar, S.3
-
65
-
-
77950645341
-
Relation between use of nucleoside reverse transcriptase inhibitors (NRTI) and risk of myocardial infarction (MI): A nested case control study using Quebec's public health insurance database (QPHID)
-
Abstract: presented at. July 19-22; Cape Town, South Africa. Abstract: #TUPEB175
-
Durand MSO, Baril JA. Relation between use of nucleoside reverse transcriptase inhibitors (NRTI) and risk of myocardial infarction (MI): a nested case control study using Quebec's public health insurance database (QPHID). Abstract: presented at: 5th IAS Conference on HIV Pathogenesis, Treatment, and Prevention. July 19-22, 2009; Cape Town, South Africa. Abstract: #TUPEB175.
-
(2009)
5th IAS Conference on HIV Pathogenesis, Treatment, and Prevention
-
-
Durand, M.S.O.1
Baril, J.A.2
-
66
-
-
77949558089
-
Abacavir use and risk of acute myocardial infarction and cerebrovascular disease in the HAART era
-
Abstract: presented at. July 19-22; Cape Town, South Africa. Abstract: #MOAB202
-
Bedimo RWA, Dreschler H, Tebas P. Abacavir use and risk of acute myocardial infarction and cerebrovascular disease in the HAART era. Abstract: presented at: 5th IAS Conference on HIV Pathogenesis, Treatment, and Prevention. July 19-22, 2009; Cape Town, South Africa. Abstract: #MOAB202.
-
(2009)
5th IAS Conference on HIV Pathogenesis Treatment and Prevention
-
-
Bedimo, R.W.A.1
Dreschler, H.2
Tebas, P.3
-
67
-
-
50649101127
-
Abacavir and increased risk of myocardial infarction
-
author reply 4-5
-
Post FA, Campbell LJ. Abacavir and increased risk of myocardial infarction. Lancet. 2008;372:803; author reply 4-5.
-
(2008)
Lancet
, vol.372
, pp. 803
-
-
Post, F.A.1
Campbell, L.J.2
-
68
-
-
71049130451
-
Inflammatory markers among abacavir and non-abacavir recipients in the Womens' Interagency HIV study and the Multicenter AIDS cohort study
-
Abstract: presented at. February 8-11; Montreal, Canada. Abstract: #150LB
-
Palella FGS, Elion R, Benning L, et al. Inflammatory markers among abacavir and non-abacavir recipients in the Womens' Interagency HIV study and the Multicenter AIDS cohort study. Abstract: presented at: 16th Conference on Retroviruses and Opportunistic Infections. February 8-11, 2009; Montreal, Canada. Abstract: #150LB.
-
(2009)
16th Conference on Retroviruses and Opportunistic Infections
-
-
Palella, F.G.S.1
Elion, R.2
Benning, L.3
-
69
-
-
77949559871
-
No evidence for recent abacavir/lamivudine use in promoting inflammation, endothelial dysfunction, hypercoaguability, or insulin resistance in virologically suppressed HIV-infected patients: A substudy of the BICOMBO randomized clinical trial
-
July 19-22; Cape Town, South Africa. Abstract: #MOAB203
-
Martinez ELM, Perez I. No evidence for recent abacavir/lamivudine use in promoting inflammation, endothelial dysfunction, hypercoaguability, or insulin resistance in virologically suppressed HIV-infected patients: a substudy of the BICOMBO randomized clinical trial. 5th IAS Conference on HIV Pathogenesis, Treatment, and Prevention. July 19-22, 2009; Cape Town, South Africa. Abstract: #MOAB203.
-
(2009)
5th IAS Conference on HIV Pathogenesis, Treatment, and Prevention
-
-
Martinez, E.L.M.1
Perez, I.2
-
70
-
-
70349769521
-
Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients
-
Hsue PY, Hunt PW, Wu Y, et al. Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients. AIDS. 2009;23:2021-2027.
-
(2009)
AIDS
, vol.23
, pp. 2021-2027
-
-
Hsue, P.Y.1
Hunt, P.W.2
Wu, Y.3
-
71
-
-
71049184974
-
Platelet hyper-reactivity in HIV-1 infected patients on abacavir-containing ART
-
Abstract: presented at. February 8-11; Montreal, Canada. Abstract: #151LB
-
Satchell C OCE, Peace A, Cotter A, Sheehan G, Tedesco T, Doran P, Powderly W, Kenny D, Mallon P. Platelet hyper-reactivity in HIV-1 infected patients on abacavir-containing ART. Abstract: presented at: 15th Conference on Retroviruses and Opportunistic Infections. February 8-11, 2009; Montreal, Canada. Abstract: #151LB.
-
(2009)
15th Conference on Retroviruses and Opportunistic Infections
-
-
Satchell, C.O.C.E.1
Peace, A.2
Cotter, A.3
Sheehan, G.4
Tedesco, T.5
Doran, P.6
Powderly, W.7
Kenny, D.8
Mallon, P.9
-
72
-
-
20844462378
-
Abacavir versus zidovudine combined with lamivudine and efavirenz, for the treatment of antiretroviral-naive HIV-infected adults
-
DeJesus E, Herrera G, Teofilo E, et al. Abacavir versus zidovudine combined with lamivudine and efavirenz, for the treatment of antiretroviral-naive HIV-infected adults. Clin Infect Dis. 2004;39:1038-1046.
-
(2004)
Clin Infect Dis.
, vol.39
, pp. 1038-1046
-
-
Dejesus, E.1
Herrera, G.2
Teofilo, E.3
-
73
-
-
33646755880
-
Efficacy and safety of a once-daily fixed-dose combination of abacavir/lamivudine compared with abacavir twice daily and lamivudine once daily as separate entities in antiretroviral-experienced HIV-1-infected patients (CAL30001 Study)
-
Lamarca A, Clumeck N, Plettenberg A, et al. Efficacy and safety of a once-daily fixed-dose combination of abacavir/lamivudine compared with abacavir twice daily and lamivudine once daily as separate entities in antiretroviral-experienced HIV-1-infected patients (CAL30001 Study). J Acquir Immune Defic Syndr. 2006;41:598-606.
-
(2006)
J Acquir Immune Defic Syndr.
, vol.41
, pp. 598-606
-
-
Lamarca, A.1
Clumeck, N.2
Plettenberg, A.3
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