-
1
-
-
58849126602
-
Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo
-
Beirowski B., Babetto E., Gilley J., Mazzola F., Conforti L., Janeckova L., Magni G., Ribchester R. R. Coleman M. P. (2009) Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo. J. Neurosci. 29, 653 668.
-
(2009)
J. Neurosci.
, vol.29
, pp. 653-668
-
-
Beirowski, B.1
Babetto, E.2
Gilley, J.3
Mazzola, F.4
Conforti, L.5
Janeckova, L.6
Magni, G.7
Ribchester, R.R.8
Coleman, M.P.9
-
2
-
-
38549134304
-
Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo
-
Chen X., Rzhetskaya M., Kareva T., Bland R., During M. J., Tank A. W., Kholodilov N. Burke R. E. (2008) Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo. J. Neurosci. 28, 672 680.
-
(2008)
J. Neurosci.
, vol.28
, pp. 672-680
-
-
Chen, X.1
Rzhetskaya, M.2
Kareva, T.3
Bland, R.4
During, M.J.5
Tank, A.W.6
Kholodilov, N.7
Burke, R.E.8
-
3
-
-
77950680730
-
Akt/PKB inhibits retrograde axonal degeneration in the nigro-striatal dopaminergic pathway in vivo
-
Cheng H. C., Oo T. F., Kareva T., Rzhetskaya M., Wang C., During M. J., Kobayashi K., Okano H., Kholodilov N. Burke R. E. (2008) Akt/PKB inhibits retrograde axonal degeneration in the nigro-striatal dopaminergic pathway in vivo. Abstr. Soc. Neurosci. 741.7.
-
(2008)
Abstr. Soc. Neurosci.
, pp. 7417
-
-
Cheng, H.C.1
Oo, T.F.2
Kareva, T.3
Rzhetskaya, M.4
Wang, C.5
During, M.J.6
Kobayashi, K.7
Okano, H.8
Kholodilov, N.9
Burke, R.E.10
-
4
-
-
77950657084
-
Clinical progression in Parkinson's disease and the neurobiology of axons
-
2010 in press
-
Cheng H. C., Ulane C. M. Burke R. E. (2009) Clinical progression in Parkinson's disease and the neurobiology of axons. Ann Neurol, 2010, in press.
-
(2009)
Ann Neurol
-
-
Cheng, H.C.1
Ulane, C.M.2
Burke, R.E.3
-
5
-
-
27644591304
-
Axon degeneration mechanisms: Commonality amid diversity
-
Coleman M. (2005) Axon degeneration mechanisms: commonality amid diversity. Nat. Rev. Neurosci. 6, 889 898.
-
(2005)
Nat. Rev. Neurosci.
, vol.6
, pp. 889-898
-
-
Coleman, M.1
-
6
-
-
0036774951
-
Axon pathology in neurological disease: A neglected therapeutic target
-
Coleman M. P. Perry V. H. (2002) Axon pathology in neurological disease: a neglected therapeutic target. Trends Neurosci. 25, 532 537.
-
(2002)
Trends Neurosci.
, vol.25
, pp. 532-537
-
-
Coleman, M.P.1
Perry, V.H.2
-
7
-
-
0034671450
-
Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine model of Parkinson's disease
-
Eberhardt O., Coelln R. V., Kugler S. et al. (2000) Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J. Neurosci. 20, 9126 9134.
-
(2000)
J. Neurosci.
, vol.20
, pp. 9126-9134
-
-
Eberhardt, O.1
Coelln, R.V.2
Kugler, S.3
-
8
-
-
0037037438
-
Medial forebrain bundle axotomy during development induces apoptosis in dopamine neurons of the substantia nigra and activation of caspases in their degenerating axons
-
El-Khodor B. F. Burke R. E. (2002) Medial forebrain bundle axotomy during development induces apoptosis in dopamine neurons of the substantia nigra and activation of caspases in their degenerating axons. J. Comp. Neurol. 452, 65 79.
-
(2002)
J. Comp. Neurol.
, vol.452
, pp. 65-79
-
-
El-Khodor, B.F.1
Burke, R.E.2
-
10
-
-
0025954066
-
Ageing and Parkinson's disease: Substantia nigra regional selectivity
-
Fearnley J. M. Lees A. J. (1991) Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114, 2283 2301.
-
(1991)
Brain
, vol.114
, pp. 2283-2301
-
-
Fearnley, J.M.1
Lees, A.J.2
-
11
-
-
33645749795
-
Motor score of the Unified Parkinson Disease Rating Scale as a good predictor of Lewy body-associated neuronal loss in the substantia nigra
-
Greffard S., Verny M., Bonnet A. M., Beinis J. Y., Gallinari C., Meaume S., Piette F., Hauw J. J. Duyckaerts C. (2006) Motor score of the Unified Parkinson Disease Rating Scale as a good predictor of Lewy body-associated neuronal loss in the substantia nigra. Arch. Neurol. 63, 584 588.
-
(2006)
Arch. Neurol.
, vol.63
, pp. 584-588
-
-
Greffard, S.1
Verny, M.2
Bonnet, A.M.3
Beinis, J.Y.4
Gallinari, C.5
Meaume, S.6
Piette, F.7
Hauw, J.J.8
Duyckaerts, C.9
-
12
-
-
33748432246
-
Wld(S) mice are protected against the Parkinsonian mimetic MPTP
-
Hasbani D. M. O'Malley K. L. (2006) Wld(S) mice are protected against the Parkinsonian mimetic MPTP. Exp. Neurol. 202, 93 99.
-
(2006)
Exp. Neurol.
, vol.202
, pp. 93-99
-
-
Hasbani, D.M.1
O'Malley, K.L.2
-
13
-
-
33744922406
-
Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning
-
Hoopfer E. D., McLaughlin T., Watts R. J., Schuldiner O., O'Leary D. D. Luo L. (2006) Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning. Neuron 50, 883 895.
-
(2006)
Neuron
, vol.50
, pp. 883-895
-
-
Hoopfer, E.D.1
McLaughlin, T.2
Watts, R.J.3
Schuldiner, O.4
O'Leary, D.D.5
Luo, L.6
-
14
-
-
0031682676
-
Biochemical aspects of Parkinson's disease
-
Hornykiewicz O. (1998) Biochemical aspects of Parkinson's disease. Neurology 51, S2 S9.
-
(1998)
Neurology
, vol.51
-
-
Hornykiewicz, O.1
-
16
-
-
0029018424
-
6-Hydroxydopamine lesion of the rat substantia nigra: Time course and morphology of cell death
-
Jeon B. S., Jackson-Lewis V. Burke R. E. (1995) 6-Hydroxydopamine lesion of the rat substantia nigra: time course and morphology of cell death. Neurodegeneration 4, 131 137.
-
(1995)
Neurodegeneration
, vol.4
, pp. 131-137
-
-
Jeon, B.S.1
Jackson-Lewis, V.2
Burke, R.E.3
-
17
-
-
18844436224
-
In vivo imaging of axonal degeneration and regeneration in the injured spinal cord
-
Kerschensteiner M., Schwab M. E., Lichtman J. W. Misgeld T. (2005) In vivo imaging of axonal degeneration and regeneration in the injured spinal cord. Nat. Med. 11, 572 577.
-
(2005)
Nat. Med.
, vol.11
, pp. 572-577
-
-
Kerschensteiner, M.1
Schwab, M.E.2
Lichtman, J.W.3
Misgeld, T.4
-
18
-
-
18844471416
-
In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease
-
Lee C. S., Samii A., Sossi V. et al. (2000) In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease. Ann. Neurol. 47, 493 503.
-
(2000)
Ann. Neurol.
, vol.47
, pp. 493-503
-
-
Lee, C.S.1
Samii, A.2
Sossi, V.3
-
19
-
-
67649813448
-
Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease
-
Li Y., Liu W., Oo T. F. et al. (2009) Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease. Nat. Neurosci. 12, 826 828.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 826-828
-
-
Li, Y.1
Liu, W.2
Oo, T.F.3
-
20
-
-
0024373441
-
Absence of Wallerian degeneration does not hinder regeneration in peripheral nerve
-
Lunn E. R., Perry V. H., Brown M. C., Rosen H. Gordon S. (1989) Absence of Wallerian degeneration does not hinder regeneration in peripheral nerve. Eur. J. Neurosci. 1, 27 33.
-
(1989)
Eur. J. Neurosci.
, vol.1
, pp. 27-33
-
-
Lunn, E.R.1
Perry, V.H.2
Brown, M.C.3
Rosen, H.4
Gordon, S.5
-
21
-
-
23244436227
-
Axon retraction and degeneration in development and disease
-
Luo L. O'Leary D. D. (2005) Axon retraction and degeneration in development and disease. Annu. Rev. Neurosci. 28, 127 156.
-
(2005)
Annu. Rev. Neurosci.
, vol.28
, pp. 127-156
-
-
Luo, L.1
O'Leary, D.D.2
-
22
-
-
0342981758
-
Correlation between neuromorphometry in the substantia nigra and clinical features in Parkinson's disease using disector counts
-
Ma S. Y., Roytta M., Rinne J. O., Collan Y. Rinne U. K. (1997) Correlation between neuromorphometry in the substantia nigra and clinical features in Parkinson's disease using disector counts. J. Neurol. Sci. 151, 83 87.
-
(1997)
J. Neurol. Sci.
, vol.151
, pp. 83-87
-
-
Ma, S.Y.1
Roytta, M.2
Rinne, J.O.3
Collan, Y.4
Rinne, U.K.5
-
23
-
-
0035195636
-
Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene
-
Mack T. G., Reiner M., Beirowski B. et al. (2001) Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene. Nat. Neurosci. 4, 1199 1206.
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 1199-1206
-
-
MacK, T.G.1
Reiner, M.2
Beirowski, B.3
-
24
-
-
0037196248
-
Genotyping methods to detect a unique neuroprotective factor (Wld(s)) for axons
-
Mi W., Conforti L. Coleman M. P. (2002) Genotyping methods to detect a unique neuroprotective factor (Wld(s)) for axons. J. Neurosci. Methods 113, 215 218.
-
(2002)
J. Neurosci. Methods
, vol.113
, pp. 215-218
-
-
Mi, W.1
Conforti, L.2
Coleman, M.P.3
-
25
-
-
13544273848
-
The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice
-
Mi W., Beirowski B., Gillingwater T. H. et al. (2005) The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice. Brain 128, 405 416.
-
(2005)
Brain
, vol.128
, pp. 405-416
-
-
Mi, W.1
Beirowski, B.2
Gillingwater, T.H.3
-
26
-
-
0037012844
-
Axonal self-destruction and neurodegeneration
-
Raff M. C., Whitmore A. V. Finn J. T. (2002) Axonal self-destruction and neurodegeneration. Science 296, 868 871.
-
(2002)
Science
, vol.296
, pp. 868-871
-
-
Raff, M.C.1
Whitmore, A.V.2
Finn, J.T.3
-
27
-
-
56749158302
-
JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration
-
Ries V., Silva R. M., Oo T. F., Cheng H. C., Rzhetskaya M., Kholodilov N., Flavell R. A., Kuan C. Y., Rakic P. Burke R. E. (2008) JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration. J. Neurochem. 107, 1578 1588.
-
(2008)
J. Neurochem.
, vol.107
, pp. 1578-1588
-
-
Ries, V.1
Silva, R.M.2
Oo, T.F.3
Cheng, H.C.4
Rzhetskaya, M.5
Kholodilov, N.6
Flavell, R.A.7
Kuan, C.Y.8
Rakic, P.9
Burke, R.E.10
-
28
-
-
1542380508
-
Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease
-
Sajadi A., Schneider B. L. Aebischer P. (2004) Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease. Curr. Biol. 14, 326 330.
-
(2004)
Curr. Biol.
, vol.14
, pp. 326-330
-
-
Sajadi, A.1
Schneider, B.L.2
Aebischer, P.3
-
29
-
-
0028220834
-
Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6 hydroxydopamine a combined retrograde tracing and immunocytochemical study in the rat
-
Sauer H. Oertel W. H. (1994) Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6 hydroxydopamine a combined retrograde tracing and immunocytochemical study in the rat. Neuroscience 59, 401 415.
-
(1994)
Neuroscience
, vol.59
, pp. 401-415
-
-
Sauer, H.1
Oertel, W.H.2
-
30
-
-
14344272346
-
Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons
-
Sawamoto K., Nakao N., Kobayashi K. et al. (2001) Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. Proc. Natl Acad. Sci. USA 98, 6423 6428.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 6423-6428
-
-
Sawamoto, K.1
Nakao, N.2
Kobayashi, K.3
-
31
-
-
0024448235
-
Striatal dopamine deficiency in Parkinson's disease: Role of aging
-
Scherman D., Desnos C., Darchen F., Pollak P., Javoy-Agid F. Agid Y. (1989) Striatal dopamine deficiency in Parkinson's disease: Role of aging. Ann. Neurol. 26, 551 557.
-
(1989)
Ann. Neurol.
, vol.26
, pp. 551-557
-
-
Scherman, D.1
Desnos, C.2
Darchen, F.3
Pollak, P.4
Javoy-Agid, F.5
Agid, Y.6
-
32
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
Selkoe D. J. (2002) Alzheimer's disease is a synaptic failure. Science 298, 789 791.
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
33
-
-
0034747230
-
The WldS protein protects against axonal degeneration: A model of gene therapy for peripheral neuropathy
-
Wang M. S., Fang G., Culver D. G., Davis A. A., Rich M. M. Glass J. D. (2001) The WldS protein protects against axonal degeneration: a model of gene therapy for peripheral neuropathy. Ann. Neurol. 50, 773 779.
-
(2001)
Ann. Neurol.
, vol.50
, pp. 773-779
-
-
Wang, M.S.1
Fang, G.2
Culver, D.G.3
Davis, A.A.4
Rich, M.M.5
Glass, J.D.6
|