메뉴 건너뛰기




Volumn 113, Issue 3, 2010, Pages 683-691

The WldS mutation delays anterograde, but not retrograde, axonal degeneration of the dopaminergic nigro-striatal pathway in vivo

Author keywords

Apoptosis; Axon; Axonopathy; Parkinson's disease; Wallerian

Indexed keywords

GENE PRODUCT; PROTEIN WLDS; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

EID: 77950648666     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06632.x     Document Type: Article
Times cited : (29)

References (33)
  • 2
    • 38549134304 scopus 로고    scopus 로고
    • Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo
    • Chen X., Rzhetskaya M., Kareva T., Bland R., During M. J., Tank A. W., Kholodilov N. Burke R. E. (2008) Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo. J. Neurosci. 28, 672 680.
    • (2008) J. Neurosci. , vol.28 , pp. 672-680
    • Chen, X.1    Rzhetskaya, M.2    Kareva, T.3    Bland, R.4    During, M.J.5    Tank, A.W.6    Kholodilov, N.7    Burke, R.E.8
  • 4
    • 77950657084 scopus 로고    scopus 로고
    • Clinical progression in Parkinson's disease and the neurobiology of axons
    • 2010 in press
    • Cheng H. C., Ulane C. M. Burke R. E. (2009) Clinical progression in Parkinson's disease and the neurobiology of axons. Ann Neurol, 2010, in press.
    • (2009) Ann Neurol
    • Cheng, H.C.1    Ulane, C.M.2    Burke, R.E.3
  • 5
    • 27644591304 scopus 로고    scopus 로고
    • Axon degeneration mechanisms: Commonality amid diversity
    • Coleman M. (2005) Axon degeneration mechanisms: commonality amid diversity. Nat. Rev. Neurosci. 6, 889 898.
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 889-898
    • Coleman, M.1
  • 6
    • 0036774951 scopus 로고    scopus 로고
    • Axon pathology in neurological disease: A neglected therapeutic target
    • Coleman M. P. Perry V. H. (2002) Axon pathology in neurological disease: a neglected therapeutic target. Trends Neurosci. 25, 532 537.
    • (2002) Trends Neurosci. , vol.25 , pp. 532-537
    • Coleman, M.P.1    Perry, V.H.2
  • 7
    • 0034671450 scopus 로고    scopus 로고
    • Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine model of Parkinson's disease
    • Eberhardt O., Coelln R. V., Kugler S. et al. (2000) Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J. Neurosci. 20, 9126 9134.
    • (2000) J. Neurosci. , vol.20 , pp. 9126-9134
    • Eberhardt, O.1    Coelln, R.V.2    Kugler, S.3
  • 8
    • 0037037438 scopus 로고    scopus 로고
    • Medial forebrain bundle axotomy during development induces apoptosis in dopamine neurons of the substantia nigra and activation of caspases in their degenerating axons
    • El-Khodor B. F. Burke R. E. (2002) Medial forebrain bundle axotomy during development induces apoptosis in dopamine neurons of the substantia nigra and activation of caspases in their degenerating axons. J. Comp. Neurol. 452, 65 79.
    • (2002) J. Comp. Neurol. , vol.452 , pp. 65-79
    • El-Khodor, B.F.1    Burke, R.E.2
  • 10
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: Substantia nigra regional selectivity
    • Fearnley J. M. Lees A. J. (1991) Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114, 2283 2301.
    • (1991) Brain , vol.114 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 11
    • 33645749795 scopus 로고    scopus 로고
    • Motor score of the Unified Parkinson Disease Rating Scale as a good predictor of Lewy body-associated neuronal loss in the substantia nigra
    • Greffard S., Verny M., Bonnet A. M., Beinis J. Y., Gallinari C., Meaume S., Piette F., Hauw J. J. Duyckaerts C. (2006) Motor score of the Unified Parkinson Disease Rating Scale as a good predictor of Lewy body-associated neuronal loss in the substantia nigra. Arch. Neurol. 63, 584 588.
    • (2006) Arch. Neurol. , vol.63 , pp. 584-588
    • Greffard, S.1    Verny, M.2    Bonnet, A.M.3    Beinis, J.Y.4    Gallinari, C.5    Meaume, S.6    Piette, F.7    Hauw, J.J.8    Duyckaerts, C.9
  • 12
    • 33748432246 scopus 로고    scopus 로고
    • Wld(S) mice are protected against the Parkinsonian mimetic MPTP
    • Hasbani D. M. O'Malley K. L. (2006) Wld(S) mice are protected against the Parkinsonian mimetic MPTP. Exp. Neurol. 202, 93 99.
    • (2006) Exp. Neurol. , vol.202 , pp. 93-99
    • Hasbani, D.M.1    O'Malley, K.L.2
  • 13
    • 33744922406 scopus 로고    scopus 로고
    • Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning
    • Hoopfer E. D., McLaughlin T., Watts R. J., Schuldiner O., O'Leary D. D. Luo L. (2006) Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning. Neuron 50, 883 895.
    • (2006) Neuron , vol.50 , pp. 883-895
    • Hoopfer, E.D.1    McLaughlin, T.2    Watts, R.J.3    Schuldiner, O.4    O'Leary, D.D.5    Luo, L.6
  • 14
    • 0031682676 scopus 로고    scopus 로고
    • Biochemical aspects of Parkinson's disease
    • Hornykiewicz O. (1998) Biochemical aspects of Parkinson's disease. Neurology 51, S2 S9.
    • (1998) Neurology , vol.51
    • Hornykiewicz, O.1
  • 16
    • 0029018424 scopus 로고
    • 6-Hydroxydopamine lesion of the rat substantia nigra: Time course and morphology of cell death
    • Jeon B. S., Jackson-Lewis V. Burke R. E. (1995) 6-Hydroxydopamine lesion of the rat substantia nigra: time course and morphology of cell death. Neurodegeneration 4, 131 137.
    • (1995) Neurodegeneration , vol.4 , pp. 131-137
    • Jeon, B.S.1    Jackson-Lewis, V.2    Burke, R.E.3
  • 17
    • 18844436224 scopus 로고    scopus 로고
    • In vivo imaging of axonal degeneration and regeneration in the injured spinal cord
    • Kerschensteiner M., Schwab M. E., Lichtman J. W. Misgeld T. (2005) In vivo imaging of axonal degeneration and regeneration in the injured spinal cord. Nat. Med. 11, 572 577.
    • (2005) Nat. Med. , vol.11 , pp. 572-577
    • Kerschensteiner, M.1    Schwab, M.E.2    Lichtman, J.W.3    Misgeld, T.4
  • 18
    • 18844471416 scopus 로고    scopus 로고
    • In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease
    • Lee C. S., Samii A., Sossi V. et al. (2000) In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease. Ann. Neurol. 47, 493 503.
    • (2000) Ann. Neurol. , vol.47 , pp. 493-503
    • Lee, C.S.1    Samii, A.2    Sossi, V.3
  • 19
    • 67649813448 scopus 로고    scopus 로고
    • Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease
    • Li Y., Liu W., Oo T. F. et al. (2009) Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease. Nat. Neurosci. 12, 826 828.
    • (2009) Nat. Neurosci. , vol.12 , pp. 826-828
    • Li, Y.1    Liu, W.2    Oo, T.F.3
  • 20
    • 0024373441 scopus 로고
    • Absence of Wallerian degeneration does not hinder regeneration in peripheral nerve
    • Lunn E. R., Perry V. H., Brown M. C., Rosen H. Gordon S. (1989) Absence of Wallerian degeneration does not hinder regeneration in peripheral nerve. Eur. J. Neurosci. 1, 27 33.
    • (1989) Eur. J. Neurosci. , vol.1 , pp. 27-33
    • Lunn, E.R.1    Perry, V.H.2    Brown, M.C.3    Rosen, H.4    Gordon, S.5
  • 21
    • 23244436227 scopus 로고    scopus 로고
    • Axon retraction and degeneration in development and disease
    • Luo L. O'Leary D. D. (2005) Axon retraction and degeneration in development and disease. Annu. Rev. Neurosci. 28, 127 156.
    • (2005) Annu. Rev. Neurosci. , vol.28 , pp. 127-156
    • Luo, L.1    O'Leary, D.D.2
  • 22
    • 0342981758 scopus 로고    scopus 로고
    • Correlation between neuromorphometry in the substantia nigra and clinical features in Parkinson's disease using disector counts
    • Ma S. Y., Roytta M., Rinne J. O., Collan Y. Rinne U. K. (1997) Correlation between neuromorphometry in the substantia nigra and clinical features in Parkinson's disease using disector counts. J. Neurol. Sci. 151, 83 87.
    • (1997) J. Neurol. Sci. , vol.151 , pp. 83-87
    • Ma, S.Y.1    Roytta, M.2    Rinne, J.O.3    Collan, Y.4    Rinne, U.K.5
  • 23
    • 0035195636 scopus 로고    scopus 로고
    • Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene
    • Mack T. G., Reiner M., Beirowski B. et al. (2001) Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene. Nat. Neurosci. 4, 1199 1206.
    • (2001) Nat. Neurosci. , vol.4 , pp. 1199-1206
    • MacK, T.G.1    Reiner, M.2    Beirowski, B.3
  • 24
    • 0037196248 scopus 로고    scopus 로고
    • Genotyping methods to detect a unique neuroprotective factor (Wld(s)) for axons
    • Mi W., Conforti L. Coleman M. P. (2002) Genotyping methods to detect a unique neuroprotective factor (Wld(s)) for axons. J. Neurosci. Methods 113, 215 218.
    • (2002) J. Neurosci. Methods , vol.113 , pp. 215-218
    • Mi, W.1    Conforti, L.2    Coleman, M.P.3
  • 25
    • 13544273848 scopus 로고    scopus 로고
    • The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice
    • Mi W., Beirowski B., Gillingwater T. H. et al. (2005) The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice. Brain 128, 405 416.
    • (2005) Brain , vol.128 , pp. 405-416
    • Mi, W.1    Beirowski, B.2    Gillingwater, T.H.3
  • 26
    • 0037012844 scopus 로고    scopus 로고
    • Axonal self-destruction and neurodegeneration
    • Raff M. C., Whitmore A. V. Finn J. T. (2002) Axonal self-destruction and neurodegeneration. Science 296, 868 871.
    • (2002) Science , vol.296 , pp. 868-871
    • Raff, M.C.1    Whitmore, A.V.2    Finn, J.T.3
  • 27
    • 56749158302 scopus 로고    scopus 로고
    • JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration
    • Ries V., Silva R. M., Oo T. F., Cheng H. C., Rzhetskaya M., Kholodilov N., Flavell R. A., Kuan C. Y., Rakic P. Burke R. E. (2008) JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration. J. Neurochem. 107, 1578 1588.
    • (2008) J. Neurochem. , vol.107 , pp. 1578-1588
    • Ries, V.1    Silva, R.M.2    Oo, T.F.3    Cheng, H.C.4    Rzhetskaya, M.5    Kholodilov, N.6    Flavell, R.A.7    Kuan, C.Y.8    Rakic, P.9    Burke, R.E.10
  • 28
    • 1542380508 scopus 로고    scopus 로고
    • Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease
    • Sajadi A., Schneider B. L. Aebischer P. (2004) Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease. Curr. Biol. 14, 326 330.
    • (2004) Curr. Biol. , vol.14 , pp. 326-330
    • Sajadi, A.1    Schneider, B.L.2    Aebischer, P.3
  • 29
    • 0028220834 scopus 로고
    • Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6 hydroxydopamine a combined retrograde tracing and immunocytochemical study in the rat
    • Sauer H. Oertel W. H. (1994) Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6 hydroxydopamine a combined retrograde tracing and immunocytochemical study in the rat. Neuroscience 59, 401 415.
    • (1994) Neuroscience , vol.59 , pp. 401-415
    • Sauer, H.1    Oertel, W.H.2
  • 30
    • 14344272346 scopus 로고    scopus 로고
    • Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons
    • Sawamoto K., Nakao N., Kobayashi K. et al. (2001) Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. Proc. Natl Acad. Sci. USA 98, 6423 6428.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 6423-6428
    • Sawamoto, K.1    Nakao, N.2    Kobayashi, K.3
  • 32
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe D. J. (2002) Alzheimer's disease is a synaptic failure. Science 298, 789 791.
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 33
    • 0034747230 scopus 로고    scopus 로고
    • The WldS protein protects against axonal degeneration: A model of gene therapy for peripheral neuropathy
    • Wang M. S., Fang G., Culver D. G., Davis A. A., Rich M. M. Glass J. D. (2001) The WldS protein protects against axonal degeneration: a model of gene therapy for peripheral neuropathy. Ann. Neurol. 50, 773 779.
    • (2001) Ann. Neurol. , vol.50 , pp. 773-779
    • Wang, M.S.1    Fang, G.2    Culver, D.G.3    Davis, A.A.4    Rich, M.M.5    Glass, J.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.