A microwell platform for the scale-up of a multistep bioconversion to bench-scale reactors: Sitosterol side-chain cleavage

Biotechnology Journal

Volumn 5, Issue 4, 2010, Pages 402-412

  Marques, Marco P C ^a   Cabral, Joaquim M S ^a   Fernandes, Pedro ^a  

^a INSTITUTO SUPERIOR TÉCNICO   (Portugal)

Author keywords

Biochemical engineering; Bioconversion; kLa; Mycobacterium sp.; Scale up

Indexed keywords

AIR FLOW; AQUEOUS MEDIUM; BENCH SCALE REACTOR; CATALYTIC ACTIVITY; CONVERSION YIELD; FERMENTORS; INCUBATION PERIODS; KLA; MICRO WELLS; MICROWELL PLATES; MODEL SYSTEM; MULTI-STEP; ONE POT; PH MONITORING; RESTING CELLS; SCALE-UP; SIDE-CHAIN; WHOLE CELL;

BIOCHEMICAL ENGINEERING; CATALYST ACTIVITY; DISSOLUTION; DISSOLVED OXYGEN; ELECTROCHEMICAL SENSORS; MICROCHANNELS;

BIOCONVERSION;

ANDROSTENEDIONE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); OXYGEN; PHYTOSTEROL; SITOSTEROL;

AERATION; APPARATUS; ARTICLE; BIOTRANSFORMATION; CARBON SOURCE; CATALYSIS; CELL GROWTH; EXPERIMENTAL MODEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MICROWELL PLATE; MYCOBACTERIUM; NONHUMAN; PH; PRIORITY JOURNAL; REACTOR; STATISTICAL ANALYSIS;

BIOREACTORS; CELL CULTURE TECHNIQUES; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; MYCOBACTERIUM; PILOT PROJECTS; SITOSTEROLS; TESTOSTERONE;

MYCOBACTERIUM SP.;

EID: 77950639065     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.200900098     Document Type: Article

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