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Volumn 32, Issue 5, 2010, Pages 335-344

Divalent Cp15-23 vaccine enhances immune responses and protection against Cryptosporidium parvum infection

Author keywords

Cryptosporidium parvum; Divalent peptide vaccine; Immune responses

Indexed keywords

CRYPTOSPORIDIUM PARVUM VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 12; PEPTIDE VACCINE; PROTOZOAL VACCINE; RECOMBINANT PROTEIN; RECOMBINANT SPOROZOITE SURFACE PROTEIN 15-23; RECOMBINANT SPOROZOITE SURFACE PROTEIN 23; UNCLASSIFIED DRUG;

EID: 77950634844     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2009.01191.x     Document Type: Article
Times cited : (23)

References (46)
  • 1
    • 77950667887 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. 5 February 2009. Available at
    • Centers for Disease Control and Prevention. Cryptosporidiosis. 5 February 2009. Available at http://www.cdc.gov/crypto.
    • Cryptosporidiosis.
  • 3
    • 0028114613 scopus 로고
    • Major antigens of Cryptosporidium parvum recognized by serum antibodies from different infected animal species and man
    • Répérant JM, Naciri M, Iochmann S, Tilley M Bout D. Major antigens of Cryptosporidium parvum recognized by serum antibodies from different infected animal species and man. Vet Parasitol 1994 55 : 1 13.
    • (1994) Vet Parasitol , vol.55 , pp. 1-13
    • Répérant, J.M.1    Naciri, M.2    Iochmann, S.3    Tilley, M.4    Bout, D.5
  • 4
    • 0344851899 scopus 로고    scopus 로고
    • Detection of antibodies to a recombinant Cryptosporidium parvum p23 in serum and feces from neonatal calves
    • Wang HF, Swain JB, Besser TE, Jasmer D Wyatt CR. Detection of antibodies to a recombinant Cryptosporidium parvum p23 in serum and feces from neonatal calves. J Parasitol 2003 89 : 918 923.
    • (2003) J Parasitol , vol.89 , pp. 918-923
    • Wang, H.F.1    Swain, J.B.2    Besser, T.E.3    Jasmer, D.4    Wyatt, C.R.5
  • 6
    • 0033794588 scopus 로고    scopus 로고
    • A 23 kDa antigen of Cryptosporidium parvum induces a cellular immune response on in vitro stimulated spleen and mesenteric lymph node cells from infected mice
    • Bonafonte M-T, Smith LM Mead JR. A 23 kDa antigen of Cryptosporidium parvum induces a cellular immune response on in vitro stimulated spleen and mesenteric lymph node cells from infected mice. Exp Parasitol 2000 96 : 32 41.
    • (2000) Exp Parasitol , vol.96 , pp. 32-41
    • Bonafonte, M.-T.1    Smith, L.M.2    Mead, J.R.3
  • 7
    • 0034972609 scopus 로고    scopus 로고
    • Human T and B cell immunoreactivity to a recombinant 23-kDa Cryptosporidium parvum antigen
    • Smith LM, Priest JW, Lammie PJ Mead JR. Human T and B cell immunoreactivity to a recombinant 23-kDa Cryptosporidium parvum antigen. J Parasitol 2001 87 : 704 707.
    • (2001) J Parasitol , vol.87 , pp. 704-707
    • Smith, L.M.1    Priest, J.W.2    Lammie, P.J.3    Mead, J.R.4
  • 8
    • 28444442991 scopus 로고    scopus 로고
    • Response of T lymphocytes from previously infected calves to recombinant Cryptosporidium parvum p23 vaccine antigen
    • Wyatt CR, Lindahl S, Austin K, Kapil S Branch J. Response of T lymphocytes from previously infected calves to recombinant Cryptosporidium parvum p23 vaccine antigen. J Parasitol 2005 91 : 1239 1242.
    • (2005) J Parasitol , vol.91 , pp. 1239-1242
    • Wyatt, C.R.1    Lindahl, S.2    Austin, K.3    Kapil, S.4    Branch, J.5
  • 9
    • 0026487176 scopus 로고
    • Immunological characterization of a 17-kDa antigen from Cryptosporidium parvum recognized early by mucosal IgA antibodies
    • Reperant JM, Naciri M, Chardes T Bout DT. Immunological characterization of a 17-kDa antigen from Cryptosporidium parvum recognized early by mucosal IgA antibodies. FEMS Microbiol Lett 1992 78 : 7 14.
    • (1992) FEMS Microbiol Lett , vol.78 , pp. 7-14
    • Reperant, J.M.1    Naciri, M.2    Chardes, T.3    Bout, D.T.4
  • 10
    • 0026034314 scopus 로고
    • Identification of a 15-kilodalton surface glycoprotein on sporozoites of Cryptosporidium parvum
    • Tilley M, Upton SJ, Fayer R, et al. Identification of a 15-kilodalton surface glycoprotein on sporozoites of Cryptosporidium parvum. Infect Immun 1991 59 : 1002 1007.
    • (1991) Infect Immun , vol.59 , pp. 1002-1007
    • Tilley, M.1    Upton, S.J.2    Fayer, R.3
  • 11
    • 0024983813 scopus 로고
    • Analysis of the kinetics, isotypes and specificity of serum and coproantibody in lambs infected with Cryptosporidium parvum
    • Hill BD, Blewett DA, Dawson AM, et al. Analysis of the kinetics, isotypes and specificity of serum and coproantibody in lambs infected with Cryptosporidium parvum. Res Vet Sci 1990 48 : 76 81.
    • (1990) Res Vet Sci , vol.48 , pp. 76-81
    • Hill, B.D.1    Blewett, D.A.2    Dawson, A.M.3
  • 12
    • 0034735774 scopus 로고    scopus 로고
    • Development of a preventive vaccine for Ebola virus infection in primates
    • Sullivan NJ, Sanchez A, Rollin PE, Yang ZY Nabel GJ. Development of a preventive vaccine for Ebola virus infection in primates. Nature 2000 408 : 605 609.
    • (2000) Nature , vol.408 , pp. 605-609
    • Sullivan, N.J.1    Sanchez, A.2    Rollin, P.E.3    Yang, Z.Y.4    Nabel, G.J.5
  • 13
    • 10244259234 scopus 로고    scopus 로고
    • Improved purification methods for calf-derived Cryptosporidium parvum oocysts using discontinuous sucrose and cesium chloride gradients
    • Arrowood MJ Donaldson K. Improved purification methods for calf-derived Cryptosporidium parvum oocysts using discontinuous sucrose and cesium chloride gradients. J Eukaryot Microbiol 1996 43 (Suppl. 89 90.
    • (1996) J Eukaryot Microbiol , vol.43 , Issue.SUPPL. , pp. 89-90
    • Arrowood, M.J.1    Donaldson, K.2
  • 14
    • 0032953877 scopus 로고    scopus 로고
    • Detection by enzyme immunoassay of serum immunoglobulin G antibodies that recognize specific Cryptosporidium parvum antigen
    • Priest JW, Kwon JP, Moss DM, et al. Detection by enzyme immunoassay of serum immunoglobulin G antibodies that recognize specific Cryptosporidium parvum antigen. J Clin Microbiol 1999 37 : 1385 1392.
    • (1999) J Clin Microbiol , vol.37 , pp. 1385-1392
    • Priest, J.W.1    Kwon, J.P.2    Moss, D.M.3
  • 15
    • 77950662818 scopus 로고    scopus 로고
    • Establishment of cDNA library of Cryptosporidium parvum and cloning of p23 and CP15/60
    • Xu WD, Zhang XC Kong QC. Establishment of cDNA library of Cryptosporidium parvum and cloning of p23 and CP15/60. Chin J Parasitol Parasitic Dis 2002 20 : 281 284.
    • (2002) Chin J Parasitol Parasitic Dis , vol.20 , pp. 281-284
    • Xu, W.D.1    Zhang, X.C.2    Kong, Q.C.3
  • 17
    • 9644264079 scopus 로고    scopus 로고
    • Present and future control of cryptosporidiosis in humans and animals
    • Jenkins MC. Present and future control of cryptosporidiosis in humans and animals. Expert Rev Vaccines 2004 3 : 669 671.
    • (2004) Expert Rev Vaccines , vol.3 , pp. 669-671
    • Jenkins, M.C.1
  • 18
    • 0028919819 scopus 로고
    • Cryptosporidium and cryptosporidiosis in man and animals
    • O'donogue PJ. Cryptosporidium and cryptosporidiosis in man and animals. Int J Parasitol 1995 25 : 170 171.
    • (1995) Int J Parasitol , vol.25 , pp. 170-171
    • O'Donogue, P.J.1
  • 19
    • 0023899016 scopus 로고    scopus 로고
    • Antigens of Cryptosporidium sporozoites recognized by immune sera of infected animals and humans
    • Mead JR, Arrowood MJ Sterling CR. Antigens of Cryptosporidium sporozoites recognized by immune sera of infected animals and humans. J Parasitol 1998 74 : 135 143.
    • (1998) J Parasitol , vol.74 , pp. 135-143
    • Mead, J.R.1    Arrowood, M.J.2    Sterling, C.R.3
  • 21
    • 0027064942 scopus 로고
    • Cryptosporidium infection and CD4 counts
    • Flanigan T, Whalen C, Turner J, et al. Cryptosporidium infection and CD4 counts. Ann Intern Med 1992 116 : 840 842.
    • (1992) Ann Intern Med , vol.116 , pp. 840-842
    • Flanigan, T.1    Whalen, C.2    Turner, J.3
  • 22
    • 0028355549 scopus 로고
    • Enumeration of selected leukocytes in the small intestine of BALB/c mice infected with Cryptosporidium parvum
    • Boher Y, Perez-Schael I, Caceres-Dittmar G, et al. Enumeration of selected leukocytes in the small intestine of BALB/c mice infected with Cryptosporidium parvum. Am J Trop Med Hyg 1994 50 : 145 151.
    • (1994) Am J Trop Med Hyg , vol.50 , pp. 145-151
    • Boher, Y.1    Perez-Schael, I.2    Caceres-Dittmar, G.3
  • 23
    • 0021356558 scopus 로고
    • Persistent Cryptosporidium infection in congenitally athymic (nude) mice
    • Heine J, Moon HW Woodmansee DB. Persistent Cryptosporidium infection in congenitally athymic (nude) mice. Infect Immun 1984 43 : 856 859.
    • (1984) Infect Immun , vol.43 , pp. 856-859
    • Heine, J.1    Moon, H.W.2    Woodmansee, D.B.3
  • 24
    • 0028117288 scopus 로고
    • In vitro proliferation and production of gamma-interferon by murine CD4+ cells in response to Cryptosporidium antigen
    • Harp JA, Whitemire WM Sacco R. In vitro proliferation and production of gamma-interferon by murine CD4+ cells in response to Cryptosporidium antigen. J Parasitol 1994 80 : 67 72.
    • (1994) J Parasitol , vol.80 , pp. 67-72
    • Harp, J.A.1    Whitemire, W.M.2    Sacco, R.3
  • 25
    • 0032900370 scopus 로고    scopus 로고
    • Cytokine profile induced by Cryptosporidium antigen in peripheral blood mononuclear cells from immunocompetent and immunosuppressed persons with cryptosporidiosis
    • Gomez Morales MA, La Rosa G, Ludovisi A, Onori AM Pozio E. Cytokine profile induced by Cryptosporidium antigen in peripheral blood mononuclear cells from immunocompetent and immunosuppressed persons with cryptosporidiosis. J Infect Dis 1999 179 : 967 973.
    • (1999) J Infect Dis , vol.179 , pp. 967-973
    • Gomez Morales, M.A.1    La Rosa, G.2    Ludovisi, A.3    Onori, A.M.4    Pozio, E.5
  • 26
    • 0030857947 scopus 로고    scopus 로고
    • Differential T cell response induced by certain recombinant oligopeptides of herpes simplex virus glycoprotein B in mice
    • Tizard ML Chan WL. Differential T cell response induced by certain recombinant oligopeptides of herpes simplex virus glycoprotein B in mice. J Gen Virol 1997 78 : 1625 1632.
    • (1997) J Gen Virol , vol.78 , pp. 1625-1632
    • Tizard, M.L.1    Chan, W.L.2
  • 27
    • 0027250396 scopus 로고
    • + cells and gamma interferon in resolution of established Cryptosporidium parvum infection in mice
    • Chen W, Harp JA Harmsen AG. Requirements for CD4+ cells and gamma interferon in resolution of established Cryptosporidium parvum infection in mice. Infect Immun 1993 61 : 3928 3932. (Pubitemid 23260069)
    • (1993) Infection and Immunity , vol.61 , Issue.9 , pp. 3928-3932
    • Chen, W.1    Harp, J.A.2    Harmsen, A.G.3
  • 28
    • 0027160659 scopus 로고
    • Gamma interferon functions in resistance to Cryptosporidium parvum infection in severe combined immunodeficient mice
    • Chen W, Harp JA, Harmsen AG Havell EA. Gamma interferon functions in resistance to Cryptosporidium parvum infection in severe combined immunodeficient mice. Infect Immun 1993 61 : 3548 3551. (Pubitemid 23223454)
    • (1993) Infection and Immunity , vol.61 , Issue.8 , pp. 3548-3551
    • Chen, W.1    Harp, J.A.2    Harmsen, A.G.3    Havell, E.A.4
  • 29
    • 0028362107 scopus 로고
    • Cryptosporidium muris in adult mice: Adoptive transfer of immunity and protective role of CD4 versus CD8+ cells
    • McDonald V, Robinson HA, Kelly P, et al. Cryptosporidium muris in adult mice: adoptive transfer of immunity and protective role of CD4 versus CD8+ cells. Infect Immun 1994 62 : 2289 2294.
    • (1994) Infect Immun , vol.62 , pp. 2289-2294
    • McDonald, V.1    Robinson, H.A.2    Kelly, P.3
  • 30
    • 0028810463 scopus 로고
    • Resolution of cryptosporidial infection in mice correlates with parasite-specific lymphocyte proliferation associated with both TH1 and TH2 cytokine secretion
    • Tilley M, McDonald V Bancroft GJ. Resolution of cryptosporidial infection in mice correlates with parasite-specific lymphocyte proliferation associated with both TH1 and TH2 cytokine secretion. Parasite Immunol 1995 17 : 459 464.
    • (1995) Parasite Immunol , vol.17 , pp. 459-464
    • Tilley, M.1    McDonald, V.2    Bancroft, G.J.3
  • 31
    • 0030748687 scopus 로고    scopus 로고
    • Gut intraepithelial lymphocytes induce immunity against Cryptosporidium infection through a mechanism involving gamma interferon production
    • Culshaw RU, Bancroft GJ McDonald V. Gut intraepithelial lymphocytes induce immunity against Cryptosporidium infection through a mechanism involving gamma interferon production. Infect Immun 1997 65 : 3074 3079.
    • (1997) Infect Immun , vol.65 , pp. 3074-3079
    • Culshaw, R.U.1    Bancroft, G.J.2    McDonald, V.3
  • 33
    • 0030063209 scopus 로고    scopus 로고
    • IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporidium parvum
    • Urban JF Jr., Fayer R, Chen SJ, Gause WC, Gately MK Finkelman FD. IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporidium parvum. J Immunol 1996 156 : 263 268.
    • (1996) J Immunol , vol.156 , pp. 263-268
    • Urban, Jr.J.F.1    Fayer, R.2    Chen, S.J.3    Gause, W.C.4    Gately, M.K.5    Finkelman, F.D.6
  • 34
    • 4344575964 scopus 로고    scopus 로고
    • Protection against the early acute phase of Cryptosporidium parvum infection conferred by interleukin-4-induced expression of T helper 1 cytokines
    • McDonald SA, O'Grady JE, Bajaj-Elliott M, et al. Protection against the early acute phase of Cryptosporidium parvum infection conferred by interleukin-4-induced expression of T helper 1 cytokines. J Infect Dis 2004 190 : 1019 1025.
    • (2004) J Infect Dis , vol.190 , pp. 1019-1025
    • McDonald, S.A.1    O'Grady, J.E.2    Bajaj-Elliott, M.3
  • 35
    • 0032128409 scopus 로고    scopus 로고
    • Bovine T cell responses to Cryptosporidium parvum infection
    • Abrahamsen MS. Bovine T cell responses to Cryptosporidium parvum infection. Int J Parasitol 1998 28 : 1083 1088.
    • (1998) Int J Parasitol , vol.28 , pp. 1083-1088
    • Abrahamsen, M.S.1
  • 36
    • 0030963550 scopus 로고    scopus 로고
    • Cryptosporidium infection in major histocompatibility complex congenic strains of mice: Variation in susceptibility and role of T-cell cytokine responses
    • Davami MH, Bancroft GJ McDonald V. Cryptosporidium infection in major histocompatibility complex congenic strains of mice: variation in susceptibility and role of T-cell cytokine responses. Parasitol Res 1997 83 : 257 263.
    • (1997) Parasitol Res , vol.83 , pp. 257-263
    • Davami, M.H.1    Bancroft, G.J.2    McDonald, V.3
  • 37
    • 0032529212 scopus 로고    scopus 로고
    • IL-4 protects adult C57BL/6 mice from prolonged Cryptosporidium parvum infection: Analysis of CD4+alpha beta+IFN-gamma+ and CD4+alpha beta+IL-4+ lymphocytes in gut-associated lymphoid tissue during resolution of infection
    • Aguirre SA, Perryman LE, Davis WC McGuire TC. IL-4 protects adult C57BL/6 mice from prolonged Cryptosporidium parvum infection: analysis of CD4+alpha beta+IFN-gamma+ and CD4+alpha beta+IL-4+ lymphocytes in gut-associated lymphoid tissue during resolution of infection. J Immunol 1998 161 : 1891 1900.
    • (1998) J Immunol , vol.161 , pp. 1891-1900
    • Aguirre, S.A.1    Perryman, L.E.2    Davis, W.C.3    McGuire, T.C.4
  • 38
    • 33751440000 scopus 로고    scopus 로고
    • Cryptosporidium parvum: The contribution of Th1-inducing pathways to the resolution of infection of mice
    • Ehigiator HN, McNair N Mead JR. Cryptosporidium parvum: the contribution of Th1-inducing pathways to the resolution of infection of mice. Exp Parasitol 2006 115 : 107 113.
    • (2006) Exp Parasitol , vol.115 , pp. 107-113
    • Ehigiator, H.N.1    McNair, N.2    Mead, J.R.3
  • 39
    • 0031939979 scopus 로고    scopus 로고
    • Cryptosporidium parvum infection in bovine neonates: Dynamic clinical, parasitic and immunologic patterns
    • Fayer R, Gasbarre L, Pasquali P, Canals A, Almeria S Zarlenga D. Cryptosporidium parvum infection in bovine neonates: dynamic clinical, parasitic and immunologic patterns. Int J Parasitol 1998 28 : 49 56.
    • (1998) Int J Parasitol , vol.28 , pp. 49-56
    • Fayer, R.1    Gasbarre, L.2    Pasquali, P.3    Canals, A.4    Almeria, S.5    Zarlenga, D.6
  • 40
    • 0035112043 scopus 로고    scopus 로고
    • Cryptosporidium parvum-specific mucosal immune response in C57BL/6 neonatal and gamma interferon-deficient mice: Role of tumor necrosis factor alpha in protection
    • Lacroix S, Mancassola R, Naciri M Laurent F. Cryptosporidium parvum-specific mucosal immune response in C57BL/6 neonatal and gamma interferon-deficient mice: role of tumor necrosis factor alpha in protection. Infect Immun 2001 69 : 1635 1642.
    • (2001) Infect Immun , vol.69 , pp. 1635-1642
    • Lacroix, S.1    Mancassola, R.2    Naciri, M.3    Laurent, F.4
  • 41
    • 0030817862 scopus 로고    scopus 로고
    • Profiles of healing and nonhealing Cryptosporidium parvum infection in C57BL/6 mice with functional B and T lymphocytes: The extent of gamma interferon modulation determines the outcome of infection
    • Theodos CM, Sullivan CS, Griffiths JK Tzipori S. Profiles of healing and nonhealing Cryptosporidium parvum infection in C57BL/6 mice with functional B and T lymphocytes: the extent of gamma interferon modulation determines the outcome of infection. Infect Immun 1997 65 : 4761 4769.
    • (1997) Infect Immun , vol.65 , pp. 4761-4769
    • Theodos, C.M.1    Sullivan, C.S.2    Griffiths, J.K.3    Tzipori, S.4
  • 42
    • 77950650912 scopus 로고    scopus 로고
    • CD8+ T cells clear human intestinal Cryptosporidium infection through cytotoxic granule release
    • Pantenburg B, Castellanos-Gonzalez A, Dann SM, et al. CD8+ T cells clear human intestinal Cryptosporidium infection through cytotoxic granule release. J Immunol 2009 182 : 129.8.
    • (2009) J Immunol , vol.182 , pp. 1298
    • Pantenburg, B.1    Castellanos-Gonzalez, A.2    Dann, S.M.3
  • 43
    • 28444459530 scopus 로고    scopus 로고
    • An early intestinal mucosal source of Gamma interferon is associated with resistance to and control of Cryptosporidium parvum infection in mice
    • Leav BA, Yoshida M, Rogers K, et al. An early intestinal mucosal source of Gamma interferon is associated with resistance to and control of Cryptosporidium parvum infection in mice. Infect Immun 2005 73 : 8425 8428.
    • (2005) Infect Immun , vol.73 , pp. 8425-8428
    • Leav, B.A.1    Yoshida, M.2    Rogers, K.3
  • 44
    • 0033597360 scopus 로고    scopus 로고
    • Protection of calves against cryptosporidiosis with immune bovine colostrum induced by a Cryptosporidium parvum recombinant protein
    • Perryman LE, Kapil SJ, Jones ML Hunt EL. Protection of calves against cryptosporidiosis with immune bovine colostrum induced by a Cryptosporidium parvum recombinant protein. Vaccine 1999 17 : 2142 2149.
    • (1999) Vaccine , vol.17 , pp. 2142-2149
    • Perryman, L.E.1    Kapil, S.J.2    Jones, M.L.3    Hunt, E.L.4
  • 45
    • 0036801423 scopus 로고    scopus 로고
    • Susceptibility to Cryptosporidium parvum infections in cytokine- and chemokine-receptor knockout mice
    • Campbell LD, Stewart JN Mead JR. Susceptibility to Cryptosporidium parvum infections in cytokine- and chemokine-receptor knockout mice. J Parasitol 2002 88 : 1014 1016.
    • (2002) J Parasitol , vol.88 , pp. 1014-1016
    • Campbell, L.D.1    Stewart, J.N.2    Mead, J.R.3
  • 46
    • 0032882579 scopus 로고    scopus 로고
    • Nasal immunization of mice with Cryptosporidium parvum DNA induces systemic and intestinal immune response
    • Sagodira S, Iochmann S, Mevelec M-N, Dimier-Poisson I Bout D. Nasal immunization of mice with Cryptosporidium parvum DNA induces systemic and intestinal immune response. Parasite Immunol 1999 21 : 507 516.
    • (1999) Parasite Immunol , vol.21 , pp. 507-516
    • Sagodira, S.1    Iochmann, S.2    Mevelec, M.-N.3    Dimier-Poisson, I.4    Bout, D.5


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