Complexes with anti-epitope tag IgGs improve the therapeutic potential of epitope-tagged antibody fragments

Molecular Immunology

Volumn 47, Issue 7-8, 2010, Pages 1529-1534

  Xie, Xuemei ^a,b   Weisser, Nina E ^a,c   McLean, Michael D ^a   Hall, J Christopher ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Anti epitope tag IgG; Epitope tag; Fab; Fc mediated effector functions; Recombinant antibody fragment (rAbF); ScFv; Serum persistence; Therapeutic

Indexed keywords

COMPLEMENT COMPONENT C1Q; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G ANTIBODY; MYC PROTEIN; RECOMBINANT ANTIBODY; RECOMBINANT ANTIBODY FRAGMENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN BINDING; ANTIGEN SPECIFICITY; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG HALF LIFE; FEMALE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL; CELL LINE; EPITOPES; IMMUNOGLOBULIN FRAGMENTS; MICE; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RECOMBINANT PROTEINS;

MURINAE; PSEUDOMONAS AERUGINOSA;

EID: 77950627958     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.01.016     Document Type: Article

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