Human monoclonal antibodies against Pseudomonas aeruginosa lipopolysaccharide derived from transgenic mice containing megabase human immunoglobulin loci are opsonic and protective against fatal Pseudomonas sepsis

Infection and Immunity

Volumn 69, Issue 4, 2001, Pages 2223-2229

  Hemachandra, S ^a   Kamboj, K ^a   Copfer, J ^a   Pier, G ^a   Green, L L ^a   Schreiber, J R ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; EPITOPE; HUMAN IMMUNOGLOBULIN; LYMPHOCYTE ANTIGEN; MONOCLONAL ANTIBODY; OPSONIN; POLYCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENE LOCUS; GRAM NEGATIVE INFECTION; GRAM NEGATIVE SEPSIS; HUMAN; LEUKOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; T LYMPHOCYTE; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; BACTEREMIA; CHROMOSOME MAPPING; HUMANS; IMMUNIZATION; LIPOPOLYSACCHARIDES; MICE; MICE, TRANSGENIC; NEUTROPHILS; PHAGOCYTOSIS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

EID: 0035077840     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.4.2223-2229.2001     Document Type: Article

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