FLO gene-dependent phenotypes in industrial wine yeast strains

Applied Microbiology and Biotechnology

Volumn 86, Issue 3, 2010, Pages 931-945

  Govender, Patrick ^a,b   Bester, Michael ^b   Bauer, Florian F ^b  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

Adhesion; Cell wall proteins; Fermentation; FLO gene expression; Flocculation; Wine yeast

Indexed keywords

CELL WALL PROTEINS; EPIGENETIC REGULATION; FLO GENE EXPRESSION; INDUCIBLE PROMOTER; INDUSTRIAL STRAIN; OPEN READING FRAME; STABLE EXPRESSION; STATIONARY PHASE; WINE MAKING; WINE STRAINS; WINE YEAST; YEAST STRAIN;

ADHESION; APPROXIMATION THEORY; FERMENTATION; FLOCCULATION; LABORATORIES; PROTEINS; WINE; YEAST;

GENE EXPRESSION;

GLUCOSE;

ADHESION; ALLELE; BIOTECHNOLOGY; FERMENTATION; FLOCCULATION; GENE EXPRESSION; INDUSTRIAL TECHNOLOGY; PHENOTYPE; YEAST;

ARTICLE; CHROMOSOME; CONTROLLED STUDY; FERMENTATION; FUNGAL STRAIN; GENE EXPRESSION; GLUCOSE ASSAY; NONHUMAN; OPEN READING FRAME; PHENOTYPE; PROMOTER REGION; WINE; YEAST;

CELL ADHESION; DNA, FUNGAL; FERMENTATION; INDUSTRIAL MICROBIOLOGY; LECTINS; MANNOSE-BINDING LECTINS; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ANALYSIS, DNA; WINE;

EID: 77950627123     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-009-2381-1     Document Type: Article

References (48)

1. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (1995) Current protocols in molecular biology. Wiley, New York
2. Bely M, Sablayrolles JM, Barre P (1990) Automatic detection of assimilable nitrogen deficiencies during alcoholic fermentation in enological conditions. J Ferment Bioeng 70:246-252
3. Bony M, Thines-Sempoux D, Barre P, Blondin B (1997) Localization and cell surface anchoring of the Saccharomyces cerevisiae flocculation protein Flo1p. J Bacteriol 179:4929-4936
4. Caro LH, Tettelin H, Vossen JH, Ram AF, van den Ende H, Klis FM (1997) In silicio identification of glycosyl-phosphatidylinositolanchored plasma-membrane and cell wall proteins of Saccharomyces cerevisiae. Yeast 13:1477-1489 (Pubitemid 27515734)
5. Chambers P, Issaka A, Palecek SP (2004) Saccharomyces cerevisiae JEN1 promoter activity is inversely related to concentration of repressing sugar. Appl Environ Microbiol 70:8-17
6. Ciriacy M (1997) Alcohol dehydrogenases. In: Zimmermann FK, Entian K-D (eds) Yeast sugar metabolism: biochemistry, genetics, biotechnology and applications. Technomic, Lancaster, pp 213-223
7. Cunha AF, Missawa SK, Gomes LH, Reis SF, Pereira GA (2006) Control by sugar of Saccharomyces cerevisiae flocculation for industrial ethanol production. FEMS Yeast Res 6:280-287
8. D'Hautcourt O, Smart KA (1999) The measurement of brewing yeast flocculation. J Am Soc Brew Chem 57:123-128
9. De Groot PW, Hellingwerf KJ, Klis FM (2003) Genome-wide identification of fungal GPI proteins. Yeast 20:781-796
10. Du Preez JC, Mare JE, Albertyn J, Kilian SG (2001) Transcriptional repression of ADH2-regulated beta-xylanase production by ethanol in recombinant strains of Saccharomyces cerevisiae. FEMS Yeast Res 1:233-240
11. Fichtner L, Schulze F, Braus GH (2007) Differential Flo8p-dependent regulation of FLO1 and FLO11 for cell-cell and cell-substrate adherence of S. cerevisiae S288C. Mol Microbiol 66:1276-1289
12. Fidalgo M, Barrales RR, Ibeas JI, Jimenez J (2006) Adaptive evolution by mutations in the FLO11 gene. Proc Natl Acad Sci USA 103:11228-11233
13. Govender P, Domingo JL, Bester MC, Pretorius IS, Bauer FF (2008) Controlled expression of the dominant flocculation genes FLO1, FLO5, and FLO11 in Saccharomyces cerevisiae. Appl Environ Microbiol 74:6041-6052
14. Guo B, Styles CA, Feng Q, Fink GR (2000) A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and mating. Proc Natl Acad Sci USA 97:12158-12163
15. Hamada K, Fukuchi S, Arisawa M, Baba M, Kitada K (1998) Screening for glycosylphosphatidylinositol (GPI)-dependent cell wall proteins in Saccharomyces cerevisiae. Mol Gen Genet 258:53-59
16. Hinchcliffe E, Box WG, Walton EF, Appleby M (1985) The influences of cell wall hydrophobicity on the top fermenting properties of brewing yeast. Proc Eur Brew Congr 20:323-330
17. Ishigami M, Nakagawa Y, Hayakawa M, Iimura Y (2004) FLO11 is essential for flor formation caused by the C-terminal deletion of NRG1 in Saccharomyces cerevisiae. FEMS Microbiol Lett 237:425-430
18. James TC, Campbell SG, Bond UM (2002) Comparative analysis of global gene expression in lager and laboratory yeast strains grown in wort. Proc IEEE 90:1887-1899
19. Kealey JT, Liu L, Santi DV, Betlach MC, Barr PJ (1998) Production of a polyketide natural product in nonpolyketide-producing prokaryotic and eukaryotic hosts. Proc Natl Acad Sci USA 95:505-509
20. Kjeldsen T (2000) Yeast secretory expression of insulin precursors. Appl Microbiol Biotechnol 54:277-286
21. Kobayashi O, Hayashi N, Kuroki R, Sone H (1998) Region of FLO1 proteins responsible for sugar recognition. J Bacteriol 180:6503-6510 (Pubitemid 129786475)
22. Lee KM, DaSilva NA (2005) Evaluation of the Saccharomyces cerevisiae ADH2 promoter for protein synthesis. Yeast 22:431-440 (Pubitemid 40704320)
23. Lipke PN, Ovalle R (1998) Cell wall architecture in yeast: new structure and new challenges. J Bacteriol 180:3735-3740 (Pubitemid 28361564)
24. Manthey GM, Navarro MS, Bailis AM (2004) DNA fragment transplacement in Saccharomyces cerevisiae: some genetic considerations. Methods Mol Biol 262:157-172
25. Maury J, Asadollahi MA, Moller K, Clark A, Nielsen J (2005) Microbial isoprenoid production: an example of green chemistry through metabolic engineering. Adv Biochem Eng Biotechnol 100:19-51 (Pubitemid 44641523)
26. Ness F, Lavallée F, Dubourdieu D, Aigle M, Dulau L (1993) Identification of yeast strains using the polymerase chain reaction. J Sci Food Agric 62:89-94
27. Nevoigt E, Kohnke J, Fischer CR, Alper H, Stahl U, Stephanopoulos G (2006) Engineering of promoter replacement cassettes for finetuning of gene expression in Saccharomyces cerevisiae. Appl Environ Microbiol 72:5266-5273 (Pubitemid 44242378)
28. Noronha SB, Kaslow DC, Shiloach J (1998) Transition phase in the production of recombinant proteins in yeast under the ADH2 promoter: an important step for reproducible manufacturing of a malaria transmission blocking vaccine candidate. J Ind Microbiol 20:192-199 (Pubitemid 28298923)
29. Pretorius IS (2000) Tailoring wine yeast for the new millennium: novel approaches to the ancient art of winemaking. Yeast 16:675-729
30. Pretorius IS, Bauer FF (2002) Meeting the consumer challenge through genetically customized wine-yeast strains. Trends Biotechnol 20:426-432
31. Rossouw D, Naes T, Bauer FF (2008) Linking gene regulation and the exo-metabolome: a comparative transcriptomics approach to identify genes that impact on the production of volatile aroma compounds in yeast. BMC Genomics 9:530
32. Saitoh S, Ishida N, Onishi T, Tokuhiro K, Nagamori E, Kitamoto K, Takahashi H (2005) Genetically engineered wine yeast produces a high concentration of L-lactic acid of extremely high optical purity. Appl Environ Microbiol 71:2789-2792 (Pubitemid 40647029)
33. Sambrook KJ, Fritsch EF, Maniatis T (1989) Molecular cloning. A laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor
34. Smukalla S, Caldara M, Pochet N, Beauvais A, Guadagnini S, Yan C, Vinces MD, Jansen A, Prevost MC, Latgé JP, Fink GR, Foster KR, Verstrepen KJ (2008) FLO1 is a variable green beard gene that drives biofilm-like cooperation in budding yeast. Cell 135:726-737
35. Stratford M (1989) Evidence for two mechanisms of flocculation in Saccharomyces cerevisiae. Yeast 5:S441-S445
36. Stratford M, Assinder S (1991) Yeast flocculation: Flo1 and NewFlo phenotypes and receptor structure. Yeast 7:559-574
37. Teunissen AW, Steensma HY (1995) Review: the dominant flocculation genes of Saccharomyces cerevisiae constitute a new subtelomeric gene family. Yeast 11:1001-1013
38. Thomson JM, Gaucher EA, Burgan MF, De Kee DW, Li T, Aris JP, Benner SA (2005) Resurrecting ancestral alcohol dehydrogenases from yeast. Nat Genet 37:630-635 (Pubitemid 40770419)
39. Van Mulders SE, Christianen E, Saerens SM, Daenen L, Verbelen PJ, Willaert R, Verstrepen KJ, Delvaux FR (2009) Phenotypic diversity of Flo protein family-mediated adhesion in Saccharomyces cerevisiae. FEMS Yeast Res 9:178-190
40. Varela C, Cardenas J, Melo F, Agosin E (2005) Quantitative analysis of wine yeast gene expression profiles under winemaking conditions. Yeast 22:369-383 (Pubitemid 40561553)
41. Verstrepen KJ, Klis FM (2006) Flocculation, adhesion and biofilm formation in yeasts. Mol Microbiol 60:5-15
42. Verstrepen KJ, Michiels C, Derdelinckx G, Delvaux FR, Winderickx J, Thevelein JM, Bauer FF, Pretorius IS (2001) Late fermentation expression of FLO1 in Saccharomyces cerevisiae. J Am Soc Brew Chem 59:69-76 (Pubitemid 32464138)
43. Verstrepen KJ, Reynolds TB, Fink GR (2004) Origins of variation in the fungal cell surface. Nat Rev Microbiol 2:533-540
44. Verstrepen KJ, Jansen A, Lewitter F, Fink GR (2005) Intragenic tandem repeats generate functional variability. Nat Genet 37:986-990 (Pubitemid 43086157)
45. Wang D, Wang Z, Liu N, He X, Zhang B (2008) Genetic modification of industrial yeast strains to obtain controllable NewFlo flocculation property and lower diacetyl production. Biotechnol Lett 30:2013-2018
46. Watari J, TakataY, OgawaM,Murakami J,Koshino S (1991) Breeding of flocculent industrial Saccharomyces cerevisiae strains by introducing the flocculation gene FLO1. Agric Biol Chem 55:1547-1552
47. Wills C (1976) Production of yeast alcohol dehydrogenase isoenzymes by selection. Nature 261:26-29
48. Winston F, Dollard C, Ricupero-Hovasse SL (1995) Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288C. Yeast 11:53-55