Structure and dynamics changes induced by 2,2,2-trifluoro-ethanol (TFE) on the N-terminal half of hepatitis C virus core protein

Biochemistry and Cell Biology

Volumn 88, Issue 2, 2010, Pages 315-323

  Duvignaud, Jean Baptiste ^a,b   Leclerc, Denis ^b   Gagné, Stéphane M ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Folding; HCV core protein; Intrinsically unstructured protein; NMR relaxation; TFE

Indexed keywords

DICHROISM; ETHANOL; NUCLEAR MAGNETIC RESONANCE; NUCLEIC ACIDS; RNA; VIRUSES;

CIRCULAR DICHROISM; CORE PROTEINS; DYNAMIC DATA; HELICAL STRUCTURES; HEPATITIS C VIRUS; INTRINSICALLY UNSTRUCTURED PROTEINS; N-TERMINALS; NMR RELAXATION; SALT CONCENTRATION; SECONDARY STRUCTURES; STRUCTURAL CHANGE; STRUCTURE AND DYNAMICS; VIRAL RNA;

PROTEINS;

CORE PROTEIN; DETERGENT; NUCLEIC ACID; TRIFLUOROETHANOL; VIRUS PROTEIN; VIRUS RNA; NUCLEOCAPSID PROTEIN, HEPATITIS C VIRUS;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; CIRCULAR DICHROISM; CONFERENCE PAPER; HEPATITIS C VIRUS; INFORMATION PROCESSING; NUCLEAR MAGNETIC RESONANCE; PH; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

HEPATITIS C VIRUS; TRIFLUORO;

DETERGENTS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; TRIFLUOROETHANOL; VIRAL CORE PROTEINS;

EID: 77950603900     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/O09-155     Document Type: Conference Paper

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