Can scarring be turned off?

American Journal of Pathology

Volumn 176, Issue 4, 2010, Pages 1588-1591

  Davidson, Jeffrey M ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN 1; CALPAIN 2; CHEMOKINE RECEPTOR CXCR3; CXCL11 CHEMOKINE; EPIDERMAL GROWTH FACTOR; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10;

CELL ADHESION; EPIDERMIS; FIBROBLAST; FIBROSIS; KERATINOCYTE; KIDNEY FIBROSIS; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCAR FORMATION; SIGNAL TRANSDUCTION; SKIN INJURY; WOUND HEALING;

EID: 77950551499     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.100064     Document Type: Note

References (22)

1. Gurtner GC, Werner S, Barrandon Y, Longaker MT: Wound repair and regeneration. Nature 2008, 453:314-321
2. Yates CC, Krishna P, Whaley D, Bodnar R, Turner T, Wells A: Lack of CXC chemokine receptor 3 (CXCR3) signaling leads to hypertrophic and hypercellular scarring, Am J Pathol 2010, 176:1743-1755
3. Werner S, Grose R: Regulation of wound healing by growth factors and cytokines. Physiol Rev 2003, 83:835-870 (Pubitemid 36828927)
4. Shiraha H, Glading A, Gupta K, Wells A: IP-10 inhibits epidermal growth factor-induced motility by decreasing epidermal growth factor receptor-mediated calpain activity. J Cell Biol 1999, 146:243-254 (Pubitemid 29349978)
5. Satish L, Yager D, Wells A: Glu-Leu-Arg-negative CXC chemokine interferon gamma inducible protein-9 as a mediator of epidermal-dermal communication during wound repair. J Invest Dermatol 2003, 120:1110-1117 (Pubitemid 36702925)
6. Allen FD, Asnes CF, Chang P, Elson EL, Lauffenburger DA, Wells A: Epidermal growth factor induces acute matrix contraction and subsequent calpain-modulated relaxation. Wound Repair Regen 2002, 10:67-76 (Pubitemid 34496483)
7. Yates CC, Whaley D, A YC, Kulesekaran P, Hebda PA, Wells A: ELR-negative CXC chemokine CXCL11 (IP-9/I-TAC) facilitates dermal and epidermal maturation during wound repair. Am J Pathol 2008, 173:643-652
8. Yates CC, Whaley D, Hooda S, Hebda PA, Bodnar RJ, Wells A: Delayed reepithelialization and basement membrane regeneration after wounding in mice lacking CXCR3. Wound Repair Regen 2009, 17:34-41
9. Strieter RM, Gomperts BN, Keane MP: The role of CXC chemokines in pulmonary fibrosis. J Clin Invest 2007, 117:549-556 (Pubitemid 46348509)
10. Jiang D, Liang J, Hodge J, Lu B, Zhu Z, Yu S, Fan J, Gao Y, Yin Z, Homer R, Gerard C, Noble PW: Regulation of pulmonary fibrosis by chemokine receptor CXCR3. J Clin Invest 2004, 114:291-299 (Pubitemid 39071634)
11. Bujak M, Dobaczewski M, Gonzalez-Quesada C, Xia Y, Leucker T, Zymek P, Veeranna V, Tager AM, Luster AD, Frangogiannis NG: Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction. Circ Res 2009, 105:973-983
12. Romagnani P, Lasagni L, Annunziato F, Serio M, Romagnani S: CXC chemokines: the regulatory link between inflammation and angiogenesis. Trends Immunol 2004, 25:201-209 (Pubitemid 38372168)
13. Deitch EA, Wheelahan TM, Rose MP, Clothier J, Cotter J: Hypertrophic burn scars: analysis of variables. J Trauma 1983, 23:895-898 (Pubitemid 13022400)
14. Mukhopadhyay A, Tan EK, Khoo YT, Chan SY, Lim IJ, Phan TT: Conditioned medium from keloid keratinocyte/keloid fibroblast coculture induces contraction of fibroblast-populated collagen lattices. Br J Dermatol 2005, 152:639-645 (Pubitemid 40571293)
15. Phan TT, Lim IJ, Aalami O, Lorget F, Khoo A, Tan EK, Mukhopadhyay A, Longaker MT: Smad3 signalling plays an important role in keloid pathogenesis via epithelial-mesenchymal interactions. J Pathol 2005, 207:232-242 (Pubitemid 41404154)
16. Xia W, Phan TT, Lim IJ, Longaker MT, Yang GP: Complex epithelial-mesenchymal interactions modulate transforming growth factor-beta expression in keloid-derived cells. Wound Repair Regen 2004, 12:546-556 (Pubitemid 39314337)
17. Medina A, Ghaffari A, Kilani RT, Ghahary A: The role of stratifin in fibroblast-keratinocyte interaction. Mol Cell Biochem 2007, 305: 255-264
18. Lam E, Kilani RT, Li Y, Tredget EE, Ghahary A: Stratifin-induced matrix metalloproteinase-1 in fibroblast is mediated by c-fos and p38 mitogen-activated protein kinase activation. J Invest Dermatol 2005, 125:230-238 (Pubitemid 41648154)
19. Ghahary A, Karimi-Busheri F, Marcoux Y, Li Y, Tredget EE, Taghi Kilani R, Li L, Zheng J, Karami A, Keller BO, Weinfeld M: Keratinocyte-releasable stratifin functions as a potent collagenase-stimulating factor in fibroblasts. J Invest Dermatol 2004, 122:1188-1197 (Pubitemid 38651094)
20. Vracko R: Basal lamina scaffold-anatomy and significance for maintenance of orderly tissue structure. Am J Pathol 1974, 77:314-346
21. Nakaya I, Wada T, Furuichi K, Sakai N, Kitagawa K, Yokoyama H, Ishida Y, Kondo T, Sugaya T, Kawachi H, Shimizu F, Narumi S, Haino M, Gerard C, Matsushima K, Kaneko S: Blockade of IP-10/CXCR3 promotes progressive renal fibrosis. Nephron Exp Nephrol 2007, 107:e12-21
22. Aarabi S, Bhatt KA, Shi Y, Paterno J, Chang EI, Loh SA, Holmes JW, Longaker MT, Yee H, Gurtner GC: Mechanical load initiates hypertrophic scar formation through decreased cellular apoptosis. FASEB J 2007, 21:3250-3261 (Pubitemid 47565543)