Stratifin-induced matrix metalloproteinase-1 in fibroblast is mediated by c-fos and p38 mitogen-activated protein kinase activation

Journal of Investigative Dermatology

Volumn 125, Issue 2, 2005, Pages 230-238

  Lam, Eugene ^a   Kilani, Runhangiz T ^a   Li, Yunyuan ^a   Tredget, Edward E ^a   Ghahary, Aziz ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

c fos; Collagenase; Fibroblasts; Keratinocyte; MMP 1; p38 MAPK Protein 14 3 3 ; Stratifin; Wound healing

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; INTERSTITIAL COLLAGENASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN 14 3 3; PROTEIN C FOS; STRATIFIN; UNCLASSIFIED DRUG; EXONUCLEASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RECOMBINANT PROTEIN; SFN PROTEIN, HUMAN; STRESS ACTIVATED PROTEIN KINASE; TUMOR MARKER; TUMOR PROTEIN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RNA STABILITY; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; UPREGULATION; WESTERN BLOTTING; CELL CULTURE; CYTOLOGY; DNA MICROARRAY; DRUG EFFECT; ENZYMOLOGY; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

CELLS, CULTURED; EXONUCLEASES; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-FOS; RECOMBINANT PROTEINS; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL;

EID: 24344450740     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2005.23765.x     Document Type: Article

References (50)

1. Angel P, Baumann I, Stein B, Delius H, Rahmsdorf HJ, Herrlich P: 12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5′-flanking region. Mol Cell Biol 7:2256-2266, 1987a
2. Angel P, Imagawa M, Chiu R, et al: Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49:729-739, 1987b
3. Birkedal-Hansen H, Moore WG, Bodden MK, Windsor LJ, Birkedal-Hansen B, DeCarlo A, Engler JA: Matrix metalloproteinases: A review. Crit Rev Oral Biol Med 4:197-250, 1993
4. Brauchte M, Gluck D, Di Padova F, Han J, Gram H: Independent role of p38 and ERK1/2 mitogen-activated kinases in the upregulation of matrix metalloproteinase-1. Exp Cell Res 258:135-144, 2000
5. Buchwalter G, Gross C, Wasylyk B: Ets ternary complex transcription factors. Gene 324:1-14, 2004
6. Chu Y, Soski PA, Khosravi-Far R, Der CJ, Kelly K: The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation. J Biol Chem 271:6497-6501, 1996
7. Dalton S, Treisman R: Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. Cell 68:597-612, 1992
8. Franklin CC, Kraft AS: Conditional expression of the mitogen activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells. J Biol Chem 272:16917-23, 1997
9. Galanis A, Yang SH, Sharrocks AD: Selective targeting of MAPKs to the ETS domain transcription factor SAP-1. J Biol Chem 276:965-973, 2001
10. Garrington TP, Johnson GL: Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr Opin Cell Biol 11:211-218, 1999
11. Ghahary A, Karimi BF, Marcoux Y, et al: Keratinocyte Releasable 14-3-3 Protein Functions as a Potent Collagenase Stimulating Factor in Fibroblasts. J Invest Dermatol 122:1188-1197, 2004
12. Ghahary A, Marcoux Y, Karimi BF, et al: Differentiated keratinocyte releasable stratifin (14-3-3 sigma) stimulates MMP-1 expression in dermal fibroblasts. J Invest Dermatol 124:170-177, 2005
13. Ghahary A, Scott PG, Malhotra S, et al: Differential expression of type I and type II procollagen mRNA in human hypertrophic burn fibroblasts. Biomed Lett 47:169, 1992
14. Ghahary A, Shen YJ, Nedelec B, Wang R, Scott PG, Tredget EE: Collagenase production is lower in post-burn hypertrophic scar fibroblasts than in normal fibroblasts and is reduced by insulin-like growth factor-1. J Invest Dermatol 106:476-481, 1996
15. Ghahary A, Tredget EE, Chang LJ, Scott PG, Shen Q: Genetically modified dermal keratinocytes express high levels of transforming growth factor-beta1. J Invest Dermatol 110:800-805, 1998
16. Greenberg ME, Ziff EB: Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature 311:433-438, 1984
17. Gutman A, Wasylyk B: The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites. EMBO J 9:2241-2246, 1990
18. Han J, Lee JD, Bibbs L, Ulevitch RJ: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265:808-811, 1994
19. Haneda M, Sugimoto T, Kikkawa R: Mitogen-activated protein kinase phosphatase: A negative regulator of the mitogen-activated protein kinase cascade. Eur J Pharmacol 365:1-7, 1999
20. Hazzalin CA, Cuenda A, Cano E, Cohen P, Mahadevan LC: Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli. Oncogene 15:2321-2331, 1997
21. Hill CS, Treisman R: Transcriptional regulation by extracellular signals: Mechanisms and specificity. Cell 80:199-211, 1995
22. Hunter T, Karin M: The regulation of transcription by phosphorylation. Cell 70:375-387, 1992
23. Hutter D, Chen P, Barnes J, Liu Y: Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: Critical role of the p38 C-terminal domain in its negative regulation. Biochem J 352:155-163, 2000
24. Janknecht R, Ernst WH, Nordheim A: SAPIa is a nuclear target of signaling cascades involving ERKs. Oncogene 10:1209-1216, 1995
25. Janknecht R, Hunter T: Convergence of MAP kinase pathways on the ternary complex factor Sap-1 a. EMBO J 16:1620-1627, 1997a
26. Janknecht R, Hunter T: Activation of the Sap-1 a transcription factor by the c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase. J Biol Chem 272:4219-4224, 1997b
27. Kahari VM, Saarialho-Kere U: Matrix metalloproteinases in skin. Exp Dermatol 6:199-213, 1997
28. Lasa M, Abraham SM, Boucheron C, Saklatvala J, Clark AR: Dexamethasone causes sustained expression of mitogen-activated protein kinase (MARK) phosphatase 1 and phosphatase-mediated inhibition of MARK p38. Mol Cell Biol 22:7802-7811, 2002
29. Lewis TS, Shapiro PS, Ahn NG: Signal transduction through MAP kinase cascades. Adv Cancer Res 74:49-139, 1998
30. Lim M, Martinez T, Jablons D, et al: Tumor-derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38. FEBS Lett 441:88-92, 1998
31. Mauviel A: Cytokine regulation of metalloproteinase gene expression. J Cell Biochem 53:288-295, 1993
32. Moon SE, Bhagavathula N, Varani J: Keratinocyte stimulation of matrix metal-loproteinase-1 production and proliferation in fibroblasts: Regulation through mitogen-activated protein kinase signalling events. Br J Cancer 87:457-464, 2002
33. Murphy G, Knauper V, Atkinson S, et al: Matrix metalloproteinases in arthritic disease. Arthritis Res 4 (Suppl 3):S39-S49, 2002
34. Nagase H, Woessner JF Jr: Matrix metalloproteinases. J Biol Chem 274: 21491-21494, 1999
35. Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, Berman K, Cobb MH: Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions. Endocr Rev 22:153-183, 2001
36. Price MA, Rogers AE, Treisman R: Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET). EMBO J 14:2589-2601, 1995
37. Ravanti L, Heino J, Lopez-Otin C, Kahari VM: Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase. J Biol Chem 274:2446-2455, 1999
38. Reunanen N, Westermarck J, Hakkinen L, Holmstrom TH, Elo I, Eriksson JE, Kahari VM: Enhancement of fibroblast collagenase (matrix metalloproteinase-1) gene expression by ceramide is mediated by extracellular signal-regulated and stress-activated protein kinase pathways. J Biol Chem 273:5137-5145, 1998
39. Ridley SH, Sarsfield SJ, Lee JC, et al: Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: Regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels. J Immunol 158:3165-3173, 1997
40. Rousseau S, Houle F, Landry J, Huot J: p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene 15:2169-2177, 1997
41. Saarialho-Kere U: Patterns of matrix metalloproteinase and TIMP expression in chronic ulcers. Arch Dermatol Res 290 (Suppl.):S47-S54, 1998
42. Schliess F, Heinrich S, Haussinger D: Hyperosmotic induction of the mitogen-activated protein kinase phosphatase MKP-1 in H411E rat hepatoma cells. Arch Biochem Biophys 351:35-40, 1998
43. Simon C, Goepfert H, Boyd D: Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion. Cancer Res 58:1135-1139, 1998
44. Slack DN, Seternes OM, Gabrielsen M, Keyse SM: Distinct binding determinants for ERK2/p38a and JNK MAP kinases mediate catalytic activation and substrate selectivity of MAP kinase phosphatase-1. J Biol Chem 276: 16491-16500, 2001
45. Theodosiou A, Ashworth A: MAP kinase phosphatases. Genome Biol 3:3009.1-3009. 10, 2002
46. Wagner EF: Functions of AP1 (Fos/Jun) in bone development. Ann Rheum Dis 61 (Suppl. 2):ii40-2, 2002
47. Westermarck J, Holmstrom T, Ahonen M, Eriksson JE, Kahari VM: Enhancement of fibroblast collagenase-1 (MMP-1) gene expression by tumor promoter okadaic acid is mediated by stress-activated protein kinases Jun N-terminal kinase and p38. Matrix Biol 17:547-557, 1998
48. Westermarck J, Kahari VM: Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J 13:781-792, 1999
49. Westermarck J, Li S, Jaakkola P, Kallunki T, Grenman R, Kahari VM: Activation of fibroblast collagenase-1 expression by tumor cells of squamous cell carcinomas is mediated by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase-2. Cancer Res 60:7156-7162, 2000
50. Westermarck J, Seth A, Kahari VM: Differential regulation of interstitial collagen-ase (MMP-1) gene expression by ETS transcription factors. Oncogene 14:2651-2660, 1997