Inhibition of growth and induction of differentiation markers by polyphenolic molecules and histone deacetylase inhibitors in colon cancer cells

Anticancer Research

Volumn 30, Issue 2, 2010, Pages 311-318

  Lea, Michael A ^a   Ibeh, Chinwe ^a   Han, Lydia ^a   Desbordes, Charles ^a,b  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Caco 2; Colon cancer; Differentiation; Growth; Polyphenols

Indexed keywords

ALKALINE PHOSPHATASE; AMINOPEPTIDASE; BUTYRIC ACID; CYCLOHEXIMIDE; DIPEPTIDYL PEPTIDASE; ELLAGIC ACID; GALLIC ACID; HISTONE DEACETYLASE INHIBITOR; POLYPHENOL DERIVATIVE; QUERCETIN; RESVERATROL; VALPROIC ACID;

ACETYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN CACO 2; CELL STRAIN HT29; CELL STRAIN SW1116; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ACETYLATION; ALKALINE PHOSPHATASE; ANTIGENS, DIFFERENTIATION; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; FLAVONOIDS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; PHENOLS;

EID: 77950539907     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Lea MA, Ibeh C, desBordes C, Vizzotto, M, Cisneros-Zevallos L, Byrne DH, Okie W and Moyer MP: Inhibition of growth and induction of differentiation of colon cancer cells by peach and plum phenolic compounds. Anticancer Res 28: 2067-2076, 2008.
2. Cieslik E, Greda A and Adamus W: Content of polyphenols in fruit and vegetables. Food Chem 94: 135-142, 2006.
3. Manach C, Scalbert A, Morand C, Remesy C and Jimenez L: Polyphenols: food sources and bioavailability. Am J Clin Nutr 79: 727-747, 2004.
4. Nichenametla SN, Taruscio TG, Barney DL and Exon JH: A review of the effects and mechanisms of polyphenolics in cancer. Crit Rev Food Sci Nutr 46: 161-183, 2006.
5. Thomasset SC, Berry DP, Garcea G, Marczylo T, Steward WP and Gescher AJ: Dietary polyphenols phytochemicals - Promising cancer chemopreventive agents in humans? A review of their clinical properties. Int J Cancer 120: 451-458, 2006.
6. Lea MA, Randolph VM and Hodge SK: Induction of histone acetylation and growth regulation in erythroleukemia cells by 4-phenylbutyrate and structural analogs. Anticancer Res 19: 1971-1976, 1999.
7. Waldecker M, Katenburger T, Daumann H, Busch C and Schrenk D: Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon. J Nutr Biochem 19: 587-593, 2008.
8. Lea MA, Shareef A, Sura M and desBordes C: Induction of histone acetylation and inhibition of growth by phenyl alkanoic acids and structurally related molecules. Cancer Chemother Pharmacol 54: 57-63, 2004.
9. Lea MA, Ibeh C, Shah N and Moyer MP: Induction of differentiation of colon cancer cells by combined inhibition of kinases and histone deacetylase. Anticancer Res 27: 741-748, 2007.
10. Lea MA and Randolph VM: Induction of reporter gene expression by inhibitors of histone deacetylase. Anticancer Res 18: 2717-2722, 1998.
11. Lipkin M, Reddy B, Newmark H and Lamprecht SA: Dietary factors in human colorectal cancer. Ann Rev Nutr 19: 545-586, 1999.
12. Nichenametla SN, Taruscio TG, Barney DL and Exon JH: A review of the effects and mechanisms of polyphenolics in cancer. Crit Rev Food Sci Nutr 46: 161-183, 2006.
13. Kampa M, Nifli A-P, Notas G and Castanas E: Polyphenols and cancer cell growth. Rev Physiol Biochem Pharmacol 159: 79-113, 2007.
14. Wang L-S and Stoner GD: Anthocyanins and their role in cancer prevention. Cancer Lett 269: 281-290, 2008.
15. McDougal GJ, Ross HA, Ikeji M and Stewart D: Berry extracts exert different antiproliferative effects against cervical and colon cancer cells grown in vitro. J Agric Food Chem 56: 3016-3023, 2008.
16. Jing P, Bomser JA, Schwartz SJ, He J, Magnuson BA and Giusti MM: Structure-function relationships of anthocyanins from various anthocyanin-rich extracts on the inhibition of colon cancer cell growth. J Agric Food Chem 56: 9391-9398, 2008.
17. Witt O, Schulze S, Kanbach K, Roth C and Pekrun A: Tumor cell differentiation by butyrate and environmental stress. Cancer Lett 171: 173-182, 2001.
18. Orchel A, Dzierzewicz Z, Parfiniewicz B, Weglarz L and Wilczok T: Butyrate-induced differentiation of colon cancer cells is PKC and JNK dependent. Dig Dis Sci 50: 490-498, 2005.
19. Ferry DR, Smith A, Malkhandi J, Fyfe DW, deTakats PG, Anderson D, Baker J and Kerr DJ: Phase I clinical trial of the flavinoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. Clin Cancer Res 2: 659-668, 1996.
20. Walker EH, Pacold ME, Perisic O, Stephens L, Hawkins PT, Wymann MP and Williams RL: Structural determinants of phosphoinositide-3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine. Mol Cell 6: 909-919, 2000.
21. Lopez-Lazaro M: Flavonoids as anticancer agents: structure-activity relationship study. Curr Med Chem Anticancer Agents 2: 691-714, 2002.
22. Herz F, Schermer A, Halwer M and Bogart LH: Alkaline phosphatase in HT29, a human colon cancer cell line: influence of sodium butyrate and hyperosmolality. Arch Biochem Biophys 210: 581-591, 1981.
23. Morita A, Tsao D and Kim YS: Effect of sodium butyrate on alkaline phosphatase in HRT-18, a human rectal cancer cell line. Cancer Res 42: 4540-4545, 1982.
24. Herz F and Halwer M: Modulation of alkaline phosphatases in LoVo, a human colon carcinoma cell line. Biochim Biophys Acta 1013: 259-265, 1989.