-
1
-
-
0036740955
-
Expression of the vascular endothelial growth factor receptor-2/Flk-1 in breast carcinomas: correlation with proliferation
-
Nakopoulou L, Stefanaki K, Panayotopoulou E et al. Expression of the vascular endothelial growth factor receptor-2/Flk-1 in breast carcinomas: correlation with proliferation. Hum Pathol 2002; 33: 863-870.
-
(2002)
Hum Pathol
, vol.33
, pp. 863-870
-
-
Nakopoulou, L.1
Stefanaki, K.2
Panayotopoulou, E.3
-
2
-
-
0031038068
-
Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
-
Relf M, LeJeune S, Scott PA et al. Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res 1997; 57: 963-969.
-
(1997)
Cancer Res
, vol.57
, pp. 963-969
-
-
Relf, M.1
LeJeune, S.2
Scott, P.A.3
-
3
-
-
0035878753
-
High tumor levels of vascular endothelial growth factor predict poor response to systemic therapy in advanced breast cancer
-
Foekens JA, Peters HA, Grebenchtchikov N et al. High tumor levels of vascular endothelial growth factor predict poor response to systemic therapy in advanced breast cancer. Cancer Res 2001; 61: 5407-5414.
-
(2001)
Cancer Res
, vol.61
, pp. 5407-5414
-
-
Foekens, J.A.1
Peters, H.A.2
Grebenchtchikov, N.3
-
4
-
-
0027488086
-
Tissue platelet derived-growth factor (PDGF) predicts for shortened survival and treatment failure in advanced breast cancer
-
Seymour L, Dajee D, Bezwoda WR. Tissue platelet derived-growth factor (PDGF) predicts for shortened survival and treatment failure in advanced breast cancer. Breast Cancer Res Treat 1993; 26: 247-252.
-
(1993)
Breast Cancer Res Treat
, vol.26
, pp. 247-252
-
-
Seymour, L.1
Dajee, D.2
Bezwoda, W.R.3
-
5
-
-
0032806309
-
Importance of VEGF for breast cancer angiogenesis in vivo: implications from intravital microscopy of combination treatments with an anti-VEGF neutralizing monoclonal antibody and doxorubicin
-
Borgstrom P, Gold DP, Hillan KJ, Ferrara N. Importance of VEGF for breast cancer angiogenesis in vivo: implications from intravital microscopy of combination treatments with an anti-VEGF neutralizing monoclonal antibody and doxorubicin. Anticancer Res 1999; 19: 4203-4214.
-
(1999)
Anticancer Res
, vol.19
, pp. 4203-4214
-
-
Borgstrom, P.1
Gold, D.P.2
Hillan, K.J.3
Ferrara, N.4
-
6
-
-
67649651994
-
A randomized, double-blind phase II study of the oral tyrosine kinase inhibitor (TKI) axitinib (AG-013736) in combination with docetaxel (DOC) compared to DOC plus placebo (PL) in metastatic breast cancer (MBC)
-
(Abstr 1003)
-
Rugo HS, Stopeck A, Joy AA et al. A randomized, double-blind phase II study of the oral tyrosine kinase inhibitor (TKI) axitinib (AG-013736) in combination with docetaxel (DOC) compared to DOC plus placebo (PL) in metastatic breast cancer (MBC). J Clin Oncol 2007; 25 (Suppl): (Abstr 1003).
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL
-
-
Rugo, H.S.1
Stopeck, A.2
Joy, A.A.3
-
7
-
-
55249101007
-
Randomized study of pazopanib + lapatinib vs. lapatinib alone in patients with HER2-positive advanced or metastatic breast cancer
-
(Abstr 1016)
-
Slamon D, Gomez HL, Kabbinavar FF et al. Randomized study of pazopanib + lapatinib vs. lapatinib alone in patients with HER2-positive advanced or metastatic breast cancer. J Clin Oncol 2008; 26 (Suppl): (Abstr 1016).
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL
-
-
Slamon, D.1
Gomez, H.L.2
Kabbinavar, F.F.3
-
8
-
-
54249120945
-
Randomized, double-blind, placebo-controlled, phase III study of bevacizumab with docetaxel or docetaxel with placebo as firstline therapy for patients with locally recurrent or metastatic breast cancer (mBC): AVADO
-
(Abstr LBA1011)
-
Miles D, Chan A, Romieu G et al. Randomized, double-blind, placebo-controlled, phase III study of bevacizumab with docetaxel or docetaxel with placebo as firstline therapy for patients with locally recurrent or metastatic breast cancer (mBC): AVADO. J Clin Oncol 2008; 26 (Suppl): (Abstr LBA1011).
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL
-
-
Miles, D.1
Chan, A.2
Romieu, G.3
-
9
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007; 357: 2666-2676.
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
10
-
-
70249097518
-
RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab (B) for first-line treatment of HER2-negative locally recurrent or metastatic breast cancer (MBC)
-
(Abstr 1005)
-
Robert NJ, Dieras V, Glaspy J et al. RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab (B) for first-line treatment of HER2-negative locally recurrent or metastatic breast cancer (MBC). J Clin Oncol 2009; 27 (Suppl): (Abstr 1005).
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL
-
-
Robert, N.J.1
Dieras, V.2
Glaspy, J.3
-
11
-
-
33745098620
-
Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248
-
Potapova O, Laird AD, Nannini MA et al. Contribution of individual targets to the antitumor efficacy of the multitargeted receptor tyrosine kinase inhibitor SU11248. Mol Cancer Ther 2006; 5: 1280-1289.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1280-1289
-
-
Potapova, O.1
Laird, A.D.2
Nannini, M.A.3
-
12
-
-
78650874372
-
SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer
-
Abrams TJ, Lee LB, Murray LJ et al. SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer. Mol Cancer Ther 2003; 2: 471-478.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 471-478
-
-
Abrams, T.J.1
Lee, L.B.2
Murray, L.J.3
-
13
-
-
33749544080
-
An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases
-
Kim DW, Jo YS, Jung HS et al. An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases. J Clin Endocrinol Metab 2006; 91: 4070-4076.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 4070-4076
-
-
Kim, D.W.1
Jo, Y.S.2
Jung, H.S.3
-
14
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and plateletderived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship
-
Mendel DB, Laird AD, Xin X et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and plateletderived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 2003; 9: 327-337.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
-
15
-
-
9144274970
-
SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model
-
Murray LJ, Abrams TJ, Long KR et al. SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model. Clin Exp Metastasis 2003; 20: 757-766.
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 757-766
-
-
Murray, L.J.1
Abrams, T.J.2
Long, K.R.3
-
16
-
-
0345359585
-
An innovative phase I clinical study demonstrates inhibition of FLT3 phosphorylation by SU11248 in acute myeloid leukemia patients
-
O'Farrell AM, Foran JM, Fiedler W et al. An innovative phase I clinical study demonstrates inhibition of FLT3 phosphorylation by SU11248 in acute myeloid leukemia patients. Clin Cancer Res 2003; 9: 5465-5476.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5465-5476
-
-
O'Farrell, A.M.1
Foran, J.M.2
Fiedler, W.3
-
17
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
O'Farrell AM, Abrams TJ, Yuen HA et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 2003; 101: 3597-3605.
-
(2003)
Blood
, vol.101
, pp. 3597-3605
-
-
O'Farrell, A.M.1
Abrams, T.J.2
Yuen, H.A.3
-
18
-
-
0041672482
-
SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models
-
Schueneman AJ, Himmelfarb E, Geng L et al. SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res 2003; 63: 4009-4016.
-
(2003)
Cancer Res
, vol.63
, pp. 4009-4016
-
-
Schueneman, A.J.1
Himmelfarb, E.2
Geng, L.3
-
19
-
-
42949148257
-
Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
-
Burstein HJ, Elias AD, Rugo HS et al. Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane. J Clin Oncol 2008; 26: 1810-1816.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1810-1816
-
-
Burstein, H.J.1
Elias, A.D.2
Rugo, H.S.3
-
20
-
-
53549128681
-
Significant enhancements of anti-tumor efficacy of VEGF/PDGF RTKI AG-013736 in combination with docetaxel in chemo-refractory and/or orthotopic xenograft tumor models in mice
-
(Abstr 2032)
-
Hu-Lowe DD, Grazzini ML. Significant enhancements of anti-tumor efficacy of VEGF/PDGF RTKI AG-013736 in combination with docetaxel in chemo-refractory and/or orthotopic xenograft tumor models in mice. Proc Am Assoc Cancer Res 2005; 46: (Abstr 2032).
-
(2005)
Proc Am Assoc Cancer Res
, vol.46
-
-
Hu-Lowe, D.D.1
Grazzini, M.L.2
-
21
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumors
-
Therasse P, Arbuck SG, Eisenhauer EA et al. New guidelines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst 2000; 92: 205-216.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 205-216
-
-
Therasse, P.1
Arbuck, S.G.2
Eisenhauer, E.A.3
-
22
-
-
75249095343
-
Exploratory evaluation of a sequential administration of docetaxel and sunitinib in women with advanced breast cancer
-
(Abstr 6079)
-
Gianni L, Cardoso F, Mariani G et al. Exploratory evaluation of a sequential administration of docetaxel and sunitinib in women with advanced breast cancer. Breast Cancer Res Treat 2007; 106 (Suppl 1): (Abstr 6079).
-
(2007)
Breast Cancer Res Treat
, vol.106
, Issue.SUPPL 1
-
-
Gianni, L.1
Cardoso, F.2
Mariani, G.3
-
23
-
-
77953291106
-
Sunitinib plus docetaxel and trastuzumab as first-line therapy for HER2+ advanced breast cancer
-
(Abstr P-5075)
-
Cardoso F, Canon JL, Amadori D et al. Sunitinib plus docetaxel and trastuzumab as first-line therapy for HER2+ advanced breast cancer. Eur J Cancer Suppl 2009; 7(2): (Abstr P-5075).
-
(2009)
Eur J Cancer Suppl
, vol.7
, Issue.2
-
-
Cardoso, F.1
Canon, J.L.2
Amadori, D.3
-
24
-
-
50549096593
-
Gemcitabine plus paclitaxel versus paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment
-
Albain KS, Nag SM, Calderillo-Ruiz G et al. Gemcitabine plus paclitaxel versus paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment. J Clin Oncol 2008; 26: 3950-3957.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3950-3957
-
-
Albain, K.S.1
Nag, S.M.2
Calderillo-Ruiz, G.3
|