Crystal structure of the botulinum neurotoxin type G binding domain: Insight into cell surface binding

Journal of Molecular Biology

Volumn 397, Issue 5, 2010, Pages 1287-1297

  Stenmark, Pål ^a,b   Dong, Min ^c,d   Dupuy, Jérôme ^a   Chapman, Edwin R ^c   Stevens, Raymond C ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Botulinum; Ganglioside; Neurotoxin; Synaptotagmin; Toxin

Indexed keywords

BOTULINUM TOXIN; BOTULINUM TOXIN B; BOTULINUM TOXIN G; GANGLIOSIDE; GANGLIOSIDE GT 1B; SYNAPTOTAGMIN I; SYNAPTOTAGMIN II; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL SURFACE; CRYSTAL STRUCTURE; CRYSTALLIZATION; HYDROPHILICITY; HYDROPHOBICITY; MUTATIONAL ANALYSIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; RECEPTOR BINDING; SEROTYPE; X RAY CRYSTALLOGRAPHY;

EID: 77950519576     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.02.041     Document Type: Article

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