Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase

Journal of Structural Biology

Volumn 170, Issue 1, 2010, Pages 157-163

  Chiswell, Brian P ^a,b   Stiegler, Amy L ^a   Razinia, Ziba ^a   Nalibotski, Elina ^a,c   Boggon, Titus J ^a   Calderwood, David A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Stem Cell and Regenerative Medicine International   (United States)

^c ZS Associates   (United States)

Author keywords

Ankyrin repeat domain; Integrin signaling; IPP complex; LIM domain

Indexed keywords

ANKYRIN; INTEGRIN LINKED KINASE; LIM PROTEIN; PROTEIN PINCH1; PROTEIN PINCH2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GENETIC CONSERVATION; IN VITRO STUDY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANKYRIN REPEAT; BINDING, COMPETITIVE; CRYSTALLIZATION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 77950518387     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2009.12.002     Document Type: Article

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