B cells in rheumatoid arthritis

Autoimmunity Reviews

Volumn 7, Issue 2, 2007, Pages 137-142

  Bugatti, Serena ^a   Codullo, Veronica ^a   Caporali, Roberto ^a   Montecucco, Carlomaurizio ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

Autoantibodies; B lymphocytes; Lymphoid neogenesis; Rheumatoid arthritis

Indexed keywords

ANTIGEN; AUTOANTIBODY; CYTOKINE; FC RECEPTOR; IMMUNOGLOBULIN G;

ANTIBODY DETECTION; ANTIBODY PRODUCING CELL; ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; ANTIGEN PRESENTATION; B LYMPHOCYTE; CELL SURVIVAL; CYTOARCHITECTURE; CYTOKINE PRODUCTION; DIAGNOSTIC PROCEDURE; HUMAN; IMMUNE RESPONSE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MOLECULAR CLONING; PROGNOSIS; REVIEW; RHEUMATOID ARTHRITIS; SYNOVIUM; T LYMPHOCYTE;

ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNITY; B-LYMPHOCYTES; CITRULLINE; CYTOKINES; GERMINAL CENTER; HUMANS; IMMUNOGLOBULIN G; LYMPHOCYTE ACTIVATION; PROGNOSIS; RHEUMATOID FACTOR; SYNOVIAL MEMBRANE; T-LYMPHOCYTES;

EID: 36148969711     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2007.02.017     Document Type: Review

References (31)

1. Firestein G.S. Evolving concepts of rheumatoid arthritis. Nature 423 (2003) 356-361
2. Edwards J.C., Szczepanski L., Szechinski J., Filipowicz-Sosnowska A., Emery P., Close D.R., et al. Efficacy of B-cell-targeted therapy with Rituximab in patients with rheumatoid arthritis. N Engl J Med 350 (2004) 2572-2581
3. Samuels J., Ng Y., Coupillaud C., Paget D., and Meffre E. Human B cell tolerance and its failure in rheumatoid arthritis. Ann N Y Acad Sci 1062 (2005) 116-126
4. Baker K.P. BLyS - an essential survival factor for B cells: basic biology, links to pathology and therapeutic target. Autoimmun Rev 3 (2004) 368-375
5. Kim H.J., and Berek C. B cells in rheumatoid arthritis. Arthritis Res 2 (2000) 126-131
6. Baecklund E., Backlin C., Iliadou A., Granath F., Ekbom A., Amini R., et al. Characteristics of diffuse large B cell lymphomas in rheumatoid arthritis. Arthritis Rheum 54 (2006) 3774-3781
7. Dieude P., and Cornelis F. Genetic basis of rheumatoid arthritis. Jt Bone Spine 72 (2005) 520-526
8. Van Gaalen F., Ioan-Facsinay A., Huizinga T.W.J., and Toes R.E.M. The Devil in the details: the emerging role of anticitrulline autoimmunity in rheumatoid arthritis. J Immunol 175 (2005) 5575-5580
9. Sutton B., Corper A., Bonagura V., and Taussig M. The structure and origin of rheumatoid factors. Immunol Today 21 (2000) 177-183
10. Roosnek E., and Lanzavecchia A. Effective and selective presentation of antigen-antibody complexes by rheumatoid factor B cells. J Exp Med 175 (1991) 487-489
11. Leadbetter E.A., Rifkin I.R., Holhbaum A.M., Beaudette B.C., Shlomchik M.J., and Marshak-Rothstein. Cheromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416 (2002) 603-607
12. Klareskog L., Stolt P., Lundberg K., Källberg H., Bengtsson C., Grunewald J., et al. A new model for an eriology of rheumatoid arthritis. Smoking may trigger HLA-DR (Shared Epitope)-restricted immune reactions to autoantigens modified by citrullination. Arthritis Rheum 54 (2006) 38-46
13. Verpoort K.N., Jol-van der Zijde C.M., Papendrecht-van der Voort E.A.M., Ioan-Facsinay A., Drijfhout J.W., van Tol M.J.D., et al. Isotype distribution of anti-cyclic citrullinated peptide antibodies in undifferentiated arthritis and rheumatoid arthritis reflects an ongoing immune response. Arthritis Rheum 54 (2006) 3799-3808
14. Zhang Z., and Bridges Jr. S.L. Pathogenesis of rheumatoid arthritis. Role of B lymphocytes. Rheum Dis Clin North Am 27 (2001) 335-353
15. van Gaalen F.A., Linn-Rasker S.P., van Venrooij W.J., de Jong B.A., Breedveld F.C., Verweij C.L., et al. Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis: a prospective cohort study. Arthritis Rheum 50 (2004) 709-715
16. Cambridge G., Leandro M.J., Edwards J.C., Ehrenstein M.R., Salden M., Bodman-Smith M., et al. Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis. Arthritis Rheum 48 (2003) 2146-2154
17. Bobbio-Pallavicini F., Alpini C., Caporali R., Avalle S., Bugatti S., and Montecucco C. Autoantibody profile in rheumatoid arthritis during long-term infliximab treatment. Arthritis Res Ther 6 (2004) R264-R272
18. Bobbio-Pallavicini F., Caporali R., Alpini C., Avalle S., Epis O., Klersy C., et al. High IgA rheumatoid factor levels are associated with poor clinical response to TNF-α inhibitors in rheumatoid arthritis. Ann Rheum Dis 66 (2007) 302-307
19. Manzo A., Paoletti S., Carulli M., Blades M.C., Barone F., Yanni G., et al. Systematic microanatomical analysis of CXCL13 and CCL21 in situ production and progressive lymphoid organization in rheumatoid synovitis. Eur J Immunol 35 (2005) 1347-1359
20. Bugatti S., Caporali R., Manzo A., Vitolo B., Pitzalis C., and Montecucco C. Involvement of subchondral bone marrow in rheumatoid arthritis: lymphoid neogenesis and in situ relationship to subchondral bone marrow osteoclast recruitment. Arthritis Rheum 52 (2005) 3448-3459
21. Rangel-Moreno J., Hartson L., Navarro C., Gaxiola M., Selman M., and Randall T.D. Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis. J Clin Invest 116 (2006) 3183-3194
22. Canete JD, Santiago B, Cantaert T, Sanmarti R, Palacin A, Celis R, et al. Ectopic lymphoid neogenesis in psoriatic arthritis. Ann Rheum Dis in press [Electronic publication ahead of print, doi:10.1136/ard.2006.062042].
23. Seyler T.M., Park Y.W., Takemura S., Bram R.J., Kurtin P.J., Goronzy J.J., et al. BLyS and APRIL in rheumatoid arthritis. J Clin Invest 115 (2005) 3083-3092
24. Takemura S., Klimiuk P.A., Braun A., Goronzy J.J., and Weyand C.M. T cell activation in rheumatoid synovium is B cell dependent. J Immunol 167 (2001) 4710-4718
25. Duddy M.E., Alter A., and Bar-Or A. Distinct profiles of human B cell effector cytokines: a role in immune regulation?. J Immunol 172 (2004) 3422-3427
26. Mauri C., Gray D., Mushtaq N., and Londei M. Prevention of arthritis by interleukin 10-producing B cells. J Exp Med 197 (2003) 489-501
27. Klimiuk P.A., Goronzy J.J., Bjornsson J., Beckenbaugh R.D., and Weyand C.M. Tissue cytokine patterns distinguish variants of rheumatoid synovitis. Am J Pathol 151 (1997) 1311-1319
28. Drayton D.L., Liao S., Mounzer R.H., and Ruddle N.H. Lymphoid organ development: from ontogeny to neogenesis. Nat Immunol 7 (2006) 344-353
29. Luther S.A., Lopez T., Bai W., Hanahan D., and Cyster J.G. BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis. Immunity 12 (2000) 471-481
30. Takemura S., Braun A., Crowson C., Kurtin P.J., Cofield R.H., O'Fallon W.M., et al. Lymphoid neogenesis in rheumatoid synovitis. J Immunol 167 (2001) 1072-1080
31. Carlsen H.S., Baekkevold E.S., Morton H.C., Haraldsen G., and Brandtzaeg P. Monocyte-like and mature macrophages produce CXCL13 (B cell-attracting chemokine 1) in inflammatory lesions with lymphoid neogenesis. Blood 104 (2004) 3021-3027