Effect of premeal consumption of whey protein and its hydrolysate on food intake and postmeal glycemia and insulin responses in young adults

American Journal of Clinical Nutrition

Volumn 91, Issue 4, 2010, Pages 966-975

  Akhavan, Tina ^a   Luhovyy, Bohdan L ^a   Brown, Peter H ^b   Cho, Clara E ^a   Anderson, G Harvey ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b Kraft Foods Global LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; MILK PROTEIN; PROTEIN HYDROLYSATE; UNCLASSIFIED DRUG; WATER; WHEY PROTEIN;

ADULT; ARTICLE; BLOOD GLUCOSE MONITORING; CONTROLLED STUDY; FEMALE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESPONSE; MALE; MEAL; NON INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN; SATIETY; WHEY; AREA UNDER THE CURVE; BLOOD; CALORIC INTAKE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CROSSOVER PROCEDURE; DOSE RESPONSE; DRUG EFFECT; HYDROLYSIS; METABOLISM; POSTPRANDIAL STATE; PROTEIN INTAKE; PSYCHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL;

ADULT; AREA UNDER CURVE; BLOOD GLUCOSE; CROSS-OVER STUDIES; DIETARY PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY INTAKE; FEMALE; HUMANS; HYDROLYSIS; INSULIN; MALE; MILK PROTEINS; POSTPRANDIAL PERIOD; SATIETY RESPONSE; YOUNG ADULT;

EID: 77950502396     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.3945/ajcn.2009.28406     Document Type: Article

References (31)

1. Barr SI, McCarron DA, Heaney RP, et al. Effects of increased consumption of fluid milk on energy and nutrient intake, body weight, and cardiovascular risk factors in healthy older adults. J Am Diet Assoc 2000;100:810-817
2. Phillips SM, Bandini LG, Cyr H, Colclough-Douglas S, Naumova E, Must A. Dairy food consumption and body weight and fatness studied longitudinally over the adolescent period. Int J Obes Relat Metab Disord 2003;27:1106-1107 (Pubitemid 37059618)
3. Anderson GH, Moore SE. Dietary proteins in the regulation of food intake and body weight in humans. J Nutr 2004;134:974S-9S.
4. Anderson GH, Tecimer SN, Shah D, Zafar TA. Protein source, quantity, and time of consumption determine the effect of proteins on short-term food intake in young men. J Nutr 2004;134:3011-3015 (Pubitemid 39470077)
5. Luhovyy BL, Akhavan T, Anderson GH. Whey proteins in the regulation of food intake and satiety. J Am Coll Nutr 2007;26:704S-12S.
6. Akhavan T, Panahi S, Anderson GH, Luhovyy BL. Application of dairy-derived ingredients in food intake and metabolic regulation. In: Corredig M, ed. Dairy-derived ingredients: food and nutraceutical uses. London, United Kingdom: Woodhead Publishing, 2009.
7. Nuttall FQ, Mooradian AD, Gannon MC, Billington C, Krezowski P. Effect of protein ingestion on the glucose and insulin response to a standardized oral glucose load. Diabetes Care 1984;7:465-470
8. Gannon MC, Nuttall FQ, Neil BJ, Westphal SA. The insulin and glucose responses to meals of glucose plus various proteins in type II diabetic subjects. Metabolism 1988;37:1081-1088
9. Promintzer M, Krebs M. Effects of dietary protein on glucose homeostasis. Curr Opin Clin Nutr Metab Care 2006;9:463-468 (Pubitemid 44097819)
10. Hall WL, Millward DJ, Long SJ, Morgan LM. Casein and whey exert different effects on plasma amino acid profiles, gastrointestinal hormone secretion and appetite. Br J Nutr 2003;89:239-248
11. Nilsson M, Stenberg M, Frid AH, Holst JJ, Bjorck IM. Glycemia and insulinemia in healthy subjects after lactose-equivalent meals of milk and other food proteins: the role of plasma amino acids and incretins. Am J Clin Nutr 2004;80:1246-1253 (Pubitemid 41350685)
12. Frid AH, Nilsson M, Holst JJ, Bjorck IM. Effect of whey on blood glucose and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects. Am J Clin Nutr 2005;82:69-75. (Pubitemid 41716379)
13. Nilsson M, Holst JJ, Bjorck IM. Metabolic effects of amino acid mixtures and whey protein in healthy subjects: studies using glucose-equivalent drinks. Am J Clin Nutr 2007;85:996-1004. (Pubitemid 46557914)
14. Boirie Y, Dangin M, Gachon P, Vasson MP, Maubois JL, Beaufrere B. Slow and fast dietary proteins differently modulate postprandial protein accretion. Proc Natl Acad Sci USA 1997;94:14930-14935 (Pubitemid 28041477)
15. Calbet JA, Holst JJ. Gastric emptying, gastric secretion and enterogastrone response after administration of milk proteins or their peptide hydrolysates in humans. Eur J Nutr 2004;43:127-139
16. Major GC, Chaput JP, Ledoux M, et al. Recent developments in calcium-related obesity research. Obes Rev 2008;9:428-445
17. Claessens M, Saris WH, van Baak MA. Glucagon and insulin responses after ingestion of different amounts of intact and hydrolysed proteins. Br J Nutr 2008;100:61-69
18. Bowen J, Noakes M, Trenerry C, Clifton PM. Energy intake, ghrelin, and cholecystokinin after different carbohydrate and protein preloads in overweight men. J Clin Endocrinol Metab 2006;91:1477-1483
19. Ma J, Stevens JE, Cukier K, et al. Effects of a protein 'preload' on gastric emptying, glycemia, and gut hormones after a carbohydrate meal in diet-controlled type 2 diabetes. Diabetes Care 2009;32:1600-1602
20. Herman C, Polivy J. Restrained eating. In: Stunkard AJ, ed. Obesity. Philadelphia, PA: WB Saunders and Co, 1980:208-217
21. Akhavan T, Anderson GH. Effects of glucose-to-fructose ratios in solutions on subjective satiety, food intake, and satiety hormones in young men. Am J Clin Nutr 2007;86:1354-1363 (Pubitemid 350126238)
22. Escalante Pulido JM, Alpizar Salazar M. Changes in insulin sensitivity, secretion and glucose effectiveness during menstrual cycle. Arch Med Res 1999;30:19-22. (Pubitemid 29099509)
23. Hamedani A, Akhavan T, Samra RA, Anderson GH. Reduced energy intake at breakfast is not compensated for at lunch if a high-insoluble-fiber cereal replaces a low-fiber cereal. Am J Clin Nutr 2009;89:1343-1349
24. Brown NW, Ward A, Surwit R, et al. Evidence for metabolic and endocrine abnormalities in subjects recovered from anorexia nervosa. Metabolism 2003;52:296-302. (Pubitemid 36401674)
25. Vuguin P, Saenger P, Dimartino-Nardi J. Fasting glucose insulin ratio: a useful measure of insulin resistance in girls with premature adrenarche. J Clin Endocrinol Metab 2001;86:4618-4621 (Pubitemid 33020495)
26. Wolever TM, Jenkins DJ, Jenkins AL, Josse RG. The glycemic index: methodology and clinical implications. Am J Clin Nutr 1991;54:846-854
27. Horowitz M, Edelbroek MA, Wishart JM, Straathof JW. Relationship between oral glucose tolerance and gastric emptying in normal healthy subjects. Diabetologia 1993;36:857-862 (Pubitemid 23248159)
28. Rayner CK, Samsom M, Jones KL, Horowitz M. Relationships of upper gastrointestinal motor and sensory function with glycemic control. Diabetes Care 2001;24:371-381 (Pubitemid 32119141)
29. Karamanlis A, Chaikomin R, Doran S, et al. Effects of protein on glycemic and incretin responses and gastric emptying after oral glucose in healthy subjects. Am J Clin Nutr 2007;86:1364-1368 (Pubitemid 350126239)
30. Pupovac J, Anderson GH. Dietary peptides induce satiety via cholecystokinin-A and peripheral opioid receptors in rats. J Nutr 2002;132:2775-2780 (Pubitemid 35013269)
31. Anderson G. Hunger, appetite, and food intake. In: Ziegler EEFL, ed. Present knowlege in nutrition. 7th ed. Washington, DC: International Life Science Institute, 1996:13-18