Evidence for metabolic and endocrine abnormalities in subjects recovered from anorexia nervosa

Metabolism: Clinical and Experimental

Volumn 52, Issue 3, 2003, Pages 296-302

  Brown, Nigel W ^a,b,c   Ward, Anne ^a,b,c   Surwit, Richard ^a,b,c   Tiller, Jane ^a,b,c   Lightman, Stafford ^a,b,c   Treasure, Janet L ^a,b,c   Campbell, Iain C ^a,b,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b BRISTOL ROYAL INFIRMARY   (United Kingdom)

^c DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYBUTYRIC ACID; GLUCOSE; INSULIN; LEPTIN;

AMINO ACID BLOOD LEVEL; ANOREXIA NERVOSA; ARTICLE; BEHAVIOR DISORDER; BODY MASS; BODY WEIGHT; BULIMIA; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; DIET RESTRICTION; EATING HABIT; ENDOCRINE DISEASE; ENDOCRINE FUNCTION; FEMALE; GENERAL PATHOLOGICAL PARAMETERS; GLUCOSE BLOOD LEVEL; HORMONE BLOOD LEVEL; HUMAN; HYPOTHESIS; INSULIN BLOOD LEVEL; LONG TERM CARE; MEAL; MENSTRUAL CYCLE; METABOLIC DISORDER; METABOLIC PARAMETERS; PANCREAS FUNCTION; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; PSYCHOMETRY; SAMPLING; VISUAL ANALOG SCALE;

EID: 0037354657     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1053/meta.2003.50067     Document Type: Article

References (46)

1. Ratnasuriya RH, Eisler I, Szmuckler GI, et al: Anorexia nervosa: Outcome and prognostic factors after 20 years. Br J Psychiatry 158:495-502, 1991
2. Bagdade JD, Bierman EL, Porte D: The significance of basal insulin levels in the evaluation of the insulin response to glucose in diabetic and non diabetic subjects. J Clin Invest 46:1549-1557, 1967
3. Schwartz MW, Peskind E, Raskind M, et al: Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans. Nat Med 2:589-593, 1996
4. Woods S, Lotter E, McKay L, et al: Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons. Nature 282:503-505, 1979
5. Woods SC, Porte D, Bobbioni E, et al: Insulin: Its relationship to the central nervous system and to the control of food intake and body weight. Am J Clin Nutr 42:1063-1071, 1985
6. Newsholme EA, Bevan SJ, Dimitriadis GD, et al: Physiological aspects of insulin action, in Ashcroft FM, Ashcroft JH (eds): Insulin: Molecular Biology to Pathology. Oxford, UK, IRL Press, 1992, pp 151-158
7. Zhang Y, Proenca R, Maffei M, et al: Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-431, 1994
8. Lostao MP, Urdaneta E, Martinez-Anso E, et al: Presence of leptin receptors in rat small intestine and leptin effect on sugar absorption. FEBS Lett 423:302-306, 1998
9. Mueller WM, Gregoire FM, Stanhope KL, et al: Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes. Endocrinology 139:551-558, 1998
10. Wang J, Lui R, Hawkins M, et al: A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature 393:684-688, 1998
11. Leedholm LJ, Meehan WP: The psychoneuroendocrinology of diabetes mellitus in rodents. Psychoneuroendocrinology 14:275-294, 1989
12. Le Magnen J: Hunger. Cambridge, UK, Cambridge University, 1985
13. Sinha MK, Ohannesioan JP, Heiman ML, et al: Nocturnal rise of leptin in lean, obese, and non-insulin dependent diabetes mellitus subjects. J Clin Invest 97:1344-1347, 1996
14. Schwartz MW, Woods SC, Porte D: Central nervous system control of food intake. Nature 404:661-671, 2000
15. Flier J, Maratos-Flier E: Energy homeostasis and body weight. Curr Biol 10:R215-217, 2001
16. Hetherington MM: In what way is eating disordered in the eating disorder? Int Rev Psychiatr 5:33-50, 1993
17. Funahashi M, Adachi A: Glucose-responsive neurones exist within the area postrema of the rat: In vitro study on the isolated slice preparation. Brain Res Bull 32:739-744, 1993
18. Nicholaidis S, Rowland N: Metering of intravenous versus oral nutrients and regulation of energy balance. Am. J Physiol 231:661-668, 1976
19. Liu Y, Gao J-H, Liu H-L, et al: The temporal response of the brain after eating revealed by functional MRI. Nature 405:1058-1062, 2000
20. Gielkens HA, Verkijk M, Lamers CB, et al: Effects of hyperglycaemia and hyperinsulinemia on satiety in humans. Metabolism 47:321-324, 1998
21. Casper RC: Carbohydrate metabolism and its regulatory hormones in anorexia nervosa. Psychiatry Res 62:85-96, 1996
22. Ploog DW, Pirke KM: Psychobiology of anorexia nervosa. Psychol Med 17:843-859, 1987
23. Grinspoon S, Gulick T, Askari H, et al: Serum leptin levels in women with anorexia nervosa. J Clin Endocrinol Metab 81:3861-3863, 1996
24. Maffei M, Hallas J, Ravussin E, et al: Leptin levels in human and rodent: Measurement of plasma leptin and ob mRNA in obese and weight reduced subjects. Nat Med 1:1155-1161, 1995
25. Montague CT, Farooqi IS, Whitehead JP, et al: Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 387:903-908, 1997
26. Grinspoon S, Askari H, Landt M, et al: Effects of fasting and glucose infusion on basal and overnight leptin concentrations in normal-weight women. Am J Clin Nutr 66:1352-1356, 1997
27. Korbontis M, Trainer PJ, Little JA, et al: Leptin levels do not change acutely with food administration in normal or obese subjects, but are negatively correlated with pituitary-adrenal activity. Clin Endocrinol 46:751-757, 1997
28. Saladin R, De Vos P, Guerre-Millo M, et al: Transient increase in obese gene expression after food intake or insulin administration. Nature 377:527-528, 1995
29. Fairburn CG, Cooper Z: The eating disorders examination, in Fairburn CG, Wilson GT (eds): Binge Eating: Nature, Assessment, and Treatment (ed 12). New York, NY, Gilford, 1993, pp 317-360
30. Garner DM, Olmstead MP, Polivy J: Development and validation of a multidimensional eating disorder inventory for anorexia and bulimia. Int J Eat Disord 2:15-34, 1983
31. Henderson M, Freeman CPL: A self-rating scale for bulimia: The bite. Br J Psychiatry 150:18-24, 1987
32. Considine RV, Sinha MK, Heiman ML, et al: Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292-295, 1996
33. Ward A, Brown N, Lightman S, et al: Neuroendocrine, appetitive and behavioural responses to d-fenfluramine in women recovered from anorexia nervosa. Br J Psychiatry 172:351-358, 1998
34. Williamson DA, Anderson DA, Jackman LP, et al: Assessment of eating disordered thoughts, feelings and behaviors, in Alison DB (ed): Handbook for Eating Behaviors and Weight-Related Problems. Thousand Oaks, CA, 1995, pp 347-386
35. Frey J, Hebebarnd J, Muller B: Reduced body fat in long-term followed-up female patients with anorexia nervosa. J Psychiatr Res 34:83-88, 2000
36. Joannic JL, Auboiron S, Raison J, et al: How the degree of unsaturation of dietary fatty acids influences the glucose and insulin responses to different carbohydrates in mixed meals. Am J Clin Nutr 65:1427-1433, 1997
37. Abell TL, Malagelada JR: Gastric electromechanical and neurohormonal function in anorexia nervosa. Gastroenterology 93:958-965, 1987
38. Schweiger U, Warnhoff M, Pahl J, et al: Effects of carbohydrate and protein meals on plasma large neutral amino acids, glucose and insulin plasma levels of anorectic patients. Metabolism 35:938-943, 1986
39. Brown NW, Campbell IC, Treasure JL: Evidence for long term pancreatic damage in subjects who used laxatives during an episode of anorexia nervosa. Int J Eat Disord 29:236-238, 2001
40. Grinspoon S, Thomas L, Miller K, et al: Changes in regional fat redistribution and the effects of estrogen during weight gain in women with anorexia nervosa. Am J Clin Nutr 73:865-869, 2001
41. Pahl J, Pirke KM, Schweiger U, et al: Anorectic behaviour, mood, and metabolic and endocrine adaptation to starvation in anorexia nervosa during impatient treatment. Biol Psychiatry 874-878, 1985
42. Brown NW, Ward A, Treasure JL, et al: Leptin levels in anorexia nervosa (acute and long term recovered). Int J Obes 20:37, 1996 (abstr)
43. Franssila-Kallunki A, Rissanen A, Elkstrand A, et al: Fuel metabolism in anorexia nervosa and simple obesity. Metabolism. 40:689-694, 1991
44. Hebebrand J, Van Der Heydon J, Devos R, et al: Plasma concentrations of obese protein in anorexia nervosa. Hum Genet 95:1-11, 1995
45. Monteleone P, Bortolotti F, Fabrazzo M, et al: Plasma leptin response to acute fasting and refeeding in untreated women with bulimia nervosa. J Clin Endocrinol 85:2499-2503, 2000
46. Robinson PH: Perceptivity and paraceptivity during measurement of gastric emptying in anorexia and bulimia nervosa. Br J Psychiatry 154:400-405, 1989