Cadmium down-regulation of kidney Sp1 binding to mouse SGLT1 and SGLT2 gene promoters: Possible reaction of cadmium with the zinc finger domain of Sp1

Toxicology and Applied Pharmacology

Volumn 244, Issue 3, 2010, Pages 254-262

  Kothinti, Rajendra K ^a   Blodgett, Amy B ^a   Petering, David H ^a   Tabatabai, Niloofar M ^b  

^a UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Cadmium; ChIP assay; Kidney; SGLT; Sp1; Zinc finger

Indexed keywords

CADMIUM; DNA; MESSENGER RNA; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM GLUCOSE COTRANSPORTER 2; TRANSCRIPTION FACTOR SP1; ZINC; ZINC FINGER PROTEIN; SLC5A1 PROTEIN, MOUSE; SLC5A2 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CADMIUM POISONING; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; GENE SEQUENCE; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CELL CULTURE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; ANIMAL; BINDING SITE; C57BL MOUSE; CELL CULTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; KIDNEY; METABOLISM; POLLUTANT;

ANIMALS; BASE SEQUENCE; BINDING SITES; CADMIUM; CELLS, CULTURED; DOWN-REGULATION; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION REGULATION; KIDNEY; MALE; MICE; MICE, INBRED C57BL; PROMOTER REGIONS, GENETIC; SODIUM-GLUCOSE TRANSPORTER 1; SODIUM-GLUCOSE TRANSPORTER 2; SP1 TRANSCRIPTION FACTOR; ZINC; ZINC FINGERS;

EID: 77950470749     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.12.038     Document Type: Article

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