Platelet-activating factor acetylhydrolase prevents myocardial ischemia- reperfusion injury

Circulation

Volumn 100, Issue 19 SUPPL., 1999, Pages

  Morgan, Elizabeth ^b   Boyle Jr , Edward M ^b   Yun, Wang ^b   Kovacich, John C ^b   Canty, Timothy G ^b   Chi, Emil ^a   Pohlman, Timothy H ^b   Verrier, Edward D ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Box 356310 ^*

Author keywords

Endothelium derived factors; Ischemia; Myocardial infarction; Reperfusion

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RABBIT; REPERFUSION INJURY; THROMBOCYTE ACTIVATION;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ANIMALS; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; PHOSPHOLIPASES A; RABBITS;

EID: 0345633704     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. American Heart Association. 1999 Heart and Stroke Statistical Update. Dallas, Tex: American Heart Association, 1998.
2. Loucks EB, Symersky P, Qayumi AK. Platelet-activating factor antagonism: a new concept in the management of regional myocardial ischemia-reperfusion injury. J Invest Surg. 1997;10:321-338.
3. Nelson P, Stroud E, Zimmerman G, McIntyre T. PAF production by endothelial cells: a novel signal for cell-cell interaction. In: Dennis EA, Hunter T, Berridge M, eds. Cell Activation and Signal Initiation: Receptor and Phospholipase Control of Inositol Phosphate, PAF, and Eicosanoid Production. New York: A.R. Liss; 1989:297-310.
4. Shaw J, Pinckard R, Ferrigni K, McManus L, Harahan D. Activation of human neutrophils with 1-0-hexadecyl/octadecyl-2-acetyl-sn-glycerol-phosphorylcholine. J Immunol. 1981;127:1250-1255.
5. Ingraham L, Coates T, Allen J, Higgins C, Baehner R, Boxer L. Metabolic, membrane, and functional responses of human polymorphonuclear leukocytes to platelet-activating factor. Blood. 1982;59:1259-1266.
6. Zimmerman G, Prescott S, McIntyre T. Platelet-activating factor: a fluid-phase and cell associated mediator of inflammation. In: Gallin JI, Goldstein IM, Snyderman R, eds. Inflammation: Basic Principles and Clinical Correlates. New York: Raven Press; 1992;149-176.
7. Stafforini D, McIntyre T, Zimmerman G, Prescott S. Platelet activating acetylhydrolases. J Biol Chem. 1997;272:17895-17898.
8. Tjoelker L, Wilder C, Eberhardt C, Stafforini D, Dietsch G, Schimpf B, Hooper S, Trong H, Cousens L, Zimmerman G, Yamada Y, McIntyre T, Prescott S, Gray P. Anti-inflammatory properties of a platelet-activating factor acetylhydrolase II. Nature. 1995;374:549-552.
9. Piper P, Stewart A. Coronary vasoconstriction in the rat, isolated perfused heart induced by platelet-activating factor in guinea-pig perfused hearts by selective platelet-activating factor receptor antagonists. Br J Pharmacol. 1986;90:771-783.
10. Lorant D, Zimmerman G, McIntyre T, Prescott S. Platelet activating factor mediates procoagulant activity on the surface of endothelial cells by promoting leukocyte adhesion. Semin Cell Biol. 1995;6:295-303.
11. Sawa Y, Schaper J, Roth M, Nagasawa K, Ballagi G, Bleese N, Schaper W. Platelet activating factor plays an important role in reperfusion injury in myocardium: efficacy of platelet-activating factor receptor antagonist (CV-3988) as compared with leukocyte-depleted reperfusion. J Thorac Cardiovasc Surg. 1994;108:953-959.
12. Ko W, Lang D, Hawes A, Zelano J, Isom O, Krieger K. Platelet-activating factor antagonism attenuates platelet and neutrophil activation and reduces myocardial injury during coronary reperfusion. J Surg Res. 1993;55:504-515.
13. Katoh S, Toyama J, Kodama I, Koike A, Tashio A. Role of platelet activating factor in ischemia-reperfusion injury of isolate rabbit hearts: protective effect of a specific platelet activating factor antagonist, TCV-309. Cardiovasc Res. 1993;27:1430-1434.
14. Montrucchio G, Alloatti G, Mariano F. Role of platelet-activating factor in polymorphonuclear neutrophil recruitment in reperfused ischemic rabbit heart. Am J Pathol. 1993;142:471-480.
15. Nathan N, Cornu E, Denizot Y, Feiss P, Arnoux B. Serum platelet-activating factor acetylhydrolase during coronary artery bypass surgery. J Cardiothorac Vasc Anesth. 1994;8:254-255.