Plasma PAF-acetylhydrolase in patients with coronary artery disease: Results of a cross-sectional analysis

Journal of Lipid Research

Volumn 44, Issue 7, 2003, Pages 1381-1386

  Blankenberg, Stefan ^a   Stengel, Dominique ^a   Rupprecht, Hans J ^b   Bickel, Christoph ^b   Meyer, Jürgen ^b   Cambien, François ^a   Tiret, Laurence ^a   Ninio, Ewa ^a  

^a INSERM   (France)

^b NONE

Author keywords

Atherosclerosis; Inflammation; Platelet activating factor

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ANTILIPEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ADULT; ANGINA PECTORIS; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; FEMALE; HEART MUSCLE ISCHEMIA; HUMAN; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ACUTE DISEASE; ADULT; AGED; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CORONARY ARTERIOSCLEROSIS; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; MUTATION, MISSENSE; RISK; RISK FACTORS; SEX FACTORS; SYNDROME;

EID: 0142010569     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1194/jlr.M300086-JLR200     Document Type: Article

References (29)

1. Ross, R. 1999. Mechanisms of disease-Atherosclerosis, an inflammatory disease. N. Engl. J. Med. 340: 115-126.
2. Steinberg, D. 1997. Low density lipoprotein oxidation and its pathobiological significance. J. Biol. Chem. 272: 20963-20966.
3. Stafforini, D. M., T. M. McIntyre, M. E. Carter, and S. M. Prescott. 1987. Human plasma platelet-activating factor acetylhydrolase: association with lipoprotein particles and role in the degradation of platelet-activating factor. J. Biol. Chem. 262: 4215-4222.
4. Tselepis, A. D., C. Dentan, S. A. Karabina, M. J. Chapman, and E. Ninio. 1995. PAF-degrading acetylhydrolase is preferentially associated with dense LDL and VHDL-1 in human plasma. Catalytic characteristics and relation to the monocyte-derived enzyme. Arterioscler. Thromb. Vasc. Biol. 15: 1764-1773.
5. Mackness, M. I., and P. N. Durrington. 1995. HDL, its enzymes and its potential to influence lipid peroxidation. Atherosclerosis. 115: 243-253.
6. Goyal, J., K. W. Wang, M. Liu, and P. V. Subbaiah. 1997. Novel function of lecithin-cholesterol acyltransferase. Hydrolysis of oxidized polar phospholipids generated during lipoprotein oxidation. J. Biol. Chem. 272: 16231-16239.
7. Heery, P. M., M. Kozak, D. M. Stafforini, D. A. Jones, G. A. Zimmerman, and T. M. McIntyre. 1995. Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells. J. Clin. Invest. 96: 2322-2330.
8. Marathe, G. K., G. A. Zimmerman, and T. M. McIntyre. 2003. PAF-acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles. J. Biol. Chem. 278: 3937-3947.
9. Rodrigo, L., B. Mackness, P. N. Durrington, A. Hernandez, and M. I. Mackness. 2001. Hydrolysis of platelet-activating factor by human serum paraoxonase. Biochem. J. 354: 1-7.
10. Palmantier, R., A. Dulioust, H. Maiza, J. Benveniste, and E. Ninio. 1989. Biosynthesis of paf-acether. XIV. Paf-acether output in murine peritoneal macrophages is regulated by the level of acetylhydrolase. Biochem. Biophys. Res. Commun. 162: 475-482.
11. Korth, R., J. Bidault, R. Palmantier, J. Benveniste, and E. Ninio. 1993. Human platelets release a paf-acether: acetylhydrolase similar to that in plasma. Lipids. 28: 193-199.
12. Asano, K., S. Okamoto, K. Fukunaga, T. Shiomi, T. Mori, M. Iwata, Y. Ikeda, and K. Yamaguchi. 1999. Cellular source(s) of platelet-activating-factor acetylhydrolase activity in plasma. Biochem. Biophys. Res. Commun. 261: 511-514.
13. Tselepis, A. D., S-A. Karabina, D. Stengel, R. Piédagnel, M. J. Chapman, and E. Ninio. 2002. N-linked glycosylation of macrophage-derived PAF-AH is a major determinant of enzyme association with plasma HDL. J. Lipid Res. 42: 1645-1654.
14. Tjoelker, L. W., C. Wilder, C. Eberhardt, D. M. Stafforini, G. Dietsch, B. Schimpf, S. Hooper, H. Letrong, L. S. Cousens, G. A. Zimmerman, Y. Yamada, T. M. McIntyre, S. M. Prescott, and P. W. Gray. 1995. Anti-inflammatory properties of a platelet-activating factor acetylhydrolase. Nature. 374: 549-553.
15. -/- mice. FASEB J. 14: 2032-2039.
16. Quarck, R., B. De Geest, D. Stengel, A. Mertens, M. Lox, G. Theilmeier, C. Michiels, M. Raes, H. Bult, D. Collen, P. Van Veldhoven, E. Ninio, and P. Holvoet. 2001. Adenovirus-mediated gene transfer of human platelet-activating factor-acetylhydrolase prevents injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipoprotein E-deficient mice. Circulation. 103: 2495-2500.
17. Yamada, Y., S. Ichihara, T. Fujimura, and M. Yokota. 1998. Identification of the G994/T missense mutation in exon 9 of the plasma platelet-activating factor acetylhydrolase gene as an independent risk factor for coronary artery disease in Japanese men. Metabolism. 47: 177-181.
18. Satoh, K., H. Yoshida, T-a. Imaizumi, S. Takamatsu, and S. Mizuno. 1992. Platelet-activating factor acetylhydrolase in plasma lipoproteins from patients with ischemic stroke. Stroke. 23: 1090-1092.
19. Packard, C. J., D. S. O'Reilly, M. J. Caslake, A. D. McMahon, I. Ford, J. Cooney, C. H. Macphee, K. E. Suckling, M. Krishna, F. E. Wilkinson, A. Rumley, and G. D. Lowe. 2000. Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group. N. Engl. J. Med. 343: 1148-1155.
20. Blake, G. J., N. Dada, J. C. Fox, J. E. Manson, and P. M. Ridker. 2001. A prospective evaluation of lipoprotein-associated phospholipase A(2) levels and the risk of future cardiovascular events in women. J. Am. Coll. Cardiol. 38: 1302-1306.
21. Satoh, K., T. Imaizumi, H. Yoshida, M. Hiramoto, and S. Takamatsu. 1992. Increased levels of blood platelet-activating factor (PAF) and PAF-like lipids in patients with ischemic stroke. Acta Neurol. Scand. 85: 122-127.
22. Kosaka, T., M. Yamaguchi, K. Miyanaga, and K. Mizuno. 2001. Serum platelet-activating factor acetylhydrolase (PAF-AH) activity in more than 3000 healthy Japanese. Clin. Chim. Acta. 312: 179-183.
23. Tsimihodimos, V., S. A. Karabina, A. P. Tambaki, E. Bairaktari, G. Miltiadous, J. A. Goudevenos, M. A. Cariolou, M. J. Chapman, A. D. Tselepis, and M. Elisaf. 2002. Altered distribution of platelet-activating factor-acetylhydrolase activity between LDL and HDL as a function of the severity of hypercholesterolemia. J. Lipid Res. 43: 256-263.
24. Tsimihodimos, V., A. Kakafika, P. Afroditi, P. Tambaki, E. Bairaktari, M. J. Chapman, M. Elisaf, and A. D. Tselepis. 2003. Fenofibrate induces HDL-associated PAF-acetylhydrolase but attenuates enzyme activity associated with apo B-containing lipoproteins. J. Lipid Res. 44: 927-934.
25. Cao, Y., D. M. Stafforini, G. A. Zimmerman, T. M. McIntyre, and S. M. Prescott. 1998. Expression of plasma platelet-activating factor acetylhydrolase is transcriptionally regulated by mediators of inflammation. J. Biol. Chem. 273: 4012-4020.
26. Caslake, M. J., C. J. Packard, K. E. Suckling, S. D. Holmes, P. Chamberlain, and C. H. Macphee. 2000. Lipoprotein-associated phospholipase A(2), platelet-activating factor acetylhydrolase: a potential new risk factor for coronary artery disease. Atherosclerosis. 150: 413-419.
27. Yamada, Y., H. Yoshida, S. Ichihara, T. Imaizumi, K. Satoh, and M. Yokota. 2000. Correlations between plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH genotype, age and atherosclerosis in a Japanese population. Atherosclerosis. 150: 209-216.
28. Morgan, E. N., E. M. Boyle, W. Yun, J. C. Kovacich, T. G. Canty, E. Chi, T. H. Pohlman, and E. D. Verrier. 1999. Platelet-activating factor acetylhydrolase prevents myocardial ischemia-reperfusion injury. Circulation. 100: 365-368.
29. Noto, H., M. Hara, K. Karasawa, N. Iso-O, H. Satoh, M. Togo, Y. Hashimoto, Y. Yamada, T. Kosaka, M. Kawamura, S. Kimura, and K. Tsukamoto. 2003. Human plasma platelet-activating factor acetylhydrolase binds to all murine lipoproteins, conferring protection against oxidative stress. Arterioscler. Thromb. Vasc. Biol. 23: 829-835.