CD44: Target for antiangiogenesis therapy

Blood

Volumn 114, Issue 25, 2009, Pages 5114-5115

  DeLisser, Horace M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD44V6 ANTIGEN; HERMES ANTIGEN; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; CELL FUNCTION; CELL PROLIFERATION; ENZYME ACTIVATION; ENZYME ACTIVITY; IN VITRO STUDY; NOTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN VARIANT; SIGNAL TRANSDUCTION; TUMOR GROWTH;

EID: 77950410779     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-10-246397     Document Type: Note

References (16)

1. Tremmel M, Matzke A, Albrecht I, et al. A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis. Blood. 2009;114(25):5236-5244.
2. Sneath RJ, Mangham DC. The normal structure and function of CD44 and its role in neoplasia. Mol Pathol. 1998;51(4):191-200.
3. Naor D, Nedvetzki S, Golan I, Melnik L, Faitelson Y. CD44 in cancer. Crit Rev Clin Lab Sci. 2002;39(6):527-579.
4. Ponta H, Sherman L, Herrlich PA. CD44: from adhesion molecules to signalling regulators. Nat Rev Mol Cell Biol. 2003;4(1):33-45.
5. Turley EA, Noble PW, Bourguignon LY. Signaling properties of hyaluronan receptors. J Biol Chem. 2002; 277(7):4589-4592.
6. Puré E, Cuff CA. A crucial role for CD44 in inflammation. Trends Mol Med. 2001;7(5):213-221.
7. Yu Q, Stamenkovic I. Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion. Genes Dev. 1999;13(1):35-48.
8. Yu Q, Stamenkovic I. Cell surface-localized matrix metalloproteinase- 9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. Genes Dev. 2000;14(2):163-176.
9. Orian-Rousseau V, Chen L, Sleeman JP, Herrlich P, Ponta H. CD44 is required for two consecutive steps in HGF/c-Met signaling. Genes Dev. 2002;16(23):3074-3086.
10. Napier SL, Healy ZR, Schnaar RL, Konstantopoulos K. Selectin ligand expression regulates the initial vascular interactions of colon carcinoma cells: the roles of CD44v and alternative sialofucosylated selectin ligands. J Biol Chem. 2007;282(6):3433-3441.
11. Slevin M, Krupinski J, Gaffney J, et al. Hyaluronanmediated angiogenesis in vascular disease: uncovering RHAMMand CD44 receptor signaling pathways. Matrix Biol. 2007;26(1):58-68.
12. West DC, Kumar S. The effect of hyaluronate and its oligosaccharides on endothelial cell proliferation and monolayer integrity. Exp Cell Res. 1989;183(1):179-196.
13. Savani RC, Cao G, Pooler PM, Zaman A, Zhou Z, DeLisser HM. Differential involvement of the hyaluronan (HA) receptors CD44 and receptor for HA-mediated motility in endothelial cell function and angiogenesis. J Biol Chem. 2001;276(39):36770-36778.
14. Cao G, Savani RC, Fehrenbach M, et al. Involvement of endothelial CD44 during in vivo angiogenesis. Am J Pathol. 2006;169(1):325-336.
15. Mrass P, Kinjyo I, Ng LG, Reiner SL, Puré E, Weninger W. CD44 mediates successful interstitial navigation by killer T cells and enables efficient antitumor immunity. Immunity. 2008;29(6):971-985.
16. Eremina V, Jefferson JA, Kowalewska J, et al. VEGF inhibition and renal thrombotic microangiopathy.N Engl J Med. 2008;358:1129-1136.