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Volumn 15, Issue 3, 2010, Pages 1903-1917

Design, synthesis and anti-HIV integrase evaluation of N-(5-chloro-8- hydroxy-2-styrylquinolin-7-yl)benzenesulfonamide derivatives

Author keywords

HIV 1 in inhibitors; N (styryl 8 hydroxyquinolin 7 yl) benzenesulfonamide derivatives; Styrylquinoline derivatives

Indexed keywords

INTEGRASE INHIBITOR; SULFONAMIDE;

EID: 77950362404     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules15031903     Document Type: Article
Times cited : (23)

References (16)
  • 2
    • 0036050539 scopus 로고    scopus 로고
    • Strategies in the design of antiviral drugs
    • De Clercq, E. Strategies in the design of antiviral drugs. Nat. Rev. Drug Disc. 2002, 1, 13-25.
    • (2002) Nat. Rev. Drug Disc. , vol.1 , pp. 13-25
    • De Clercq, E.1
  • 3
    • 2342486748 scopus 로고    scopus 로고
    • Automation in medicinal chemistry
    • Reader, J. C. Automation in medicinal chemistry. Curr. Top. Med. Chem. 2004, 4, 671-686
    • (2004) Curr. Top. Med. Chem. , vol.4 , pp. 671-686
    • Reader, J.C.1
  • 4
    • 0036107683 scopus 로고    scopus 로고
    • Patented small molecule inhibitors of HIV-1 integrase: A 10-year saga
    • Neamati, N. Patented small molecule inhibitors of HIV-1 integrase: A 10-year saga. Exp. Opin. Ther. Pat. 2002, 12, 709-724.
    • (2002) Exp. Opin. Ther. Pat. , vol.12 , pp. 709-724
    • Neamati, N.1
  • 5
    • 0031875905 scopus 로고    scopus 로고
    • Styrylquinoline derivatives: A new class of potent HIV-1 integrase inhibitors that block HIV-1 replication in CEM cells
    • Mekouar, K.; Mouscadet, J. F.; Desmaele, D.; Subra, F.; Leh, H.; Savoure, D.; Auclair, C.; d'Angelo, J. Styrylquinoline derivatives: A new class of potent HIV-1 integrase inhibitors that block HIV-1 replication in CEM cells. J. Med. Chem. 1998, 41, 2846-2857.
    • (1998) J. Med. Chem. , vol.41 , pp. 2846-2857
    • Mekouar, K.1    Mouscadet, J.F.2    Desmaele, D.3    Subra, F.4    Leh, H.5    Savoure, D.6    Auclair, C.7    D'Angelo, J.8
  • 6
    • 0034692178 scopus 로고    scopus 로고
    • Structure-activity relationships and binding mode of styrylquinolines as potent inhibitors of HIV-1 integrase and replication of HIV-1 in cell culture
    • Zouhiri, F.; Mouscadet, J. F.; Mekouar, K.; Desmaele, D.; Savoure, D.; Leh, H.; Subra, F.; Bret, M. L.; Auclair, C.; d'Angelo, J. Structure-activity relationships and binding mode of styrylquinolines as potent inhibitors of HIV-1 integrase and replication of HIV-1 in cell culture. J. Med. Chem. 2000, 43, 1533-1540.
    • (2000) J. Med. Chem. , vol.43 , pp. 1533-1540
    • Zouhiri, F.1    Mouscadet, J.F.2    Mekouar, K.3    Desmaele, D.4    Savoure, D.5    Leh, H.6    Subra, F.7    Bret, M.L.8    Auclair, C.9    D'Angelo, J.10
  • 9
    • 3142676449 scopus 로고    scopus 로고
    • Exploring binding mode for styrylquinoline HIV-1 integrase inhibitors using comparative molecular field analysis and docking studies
    • Ma, X. H.; Zhang, X. Y.; Tan, J. J. Chen, W. Z.; Wang, C. X. Exploring binding mode for styrylquinoline HIV-1 integrase inhibitors using comparative molecular field analysis and docking studies. Acta Pharmacol. Sin. 2004, 25, 950-958.
    • (2004) Acta Pharmacol. Sin. , vol.25 , pp. 950-958
    • Ma, X.H.1    Zhang, X.Y.2    Tan, J.J.3    Chen, W.Z.4    Wang, C.X.5
  • 10
    • 70349625048 scopus 로고    scopus 로고
    • Design and synthesis of 2-styrylquinoline-7-sulfonamide derivatives as potential HIV integrase inhibitors (in Chinese)
    • Zeng, C. C.; Niu, L. T.; Ping, D. W.; Zhong, R. G. Design and synthesis of 2-styrylquinoline-7-sulfonamide derivatives as potential HIV integrase inhibitors (in Chinese). Chin. J. Org. Chem. 2009, 29, 1105-1114.
    • (2009) Chin. J. Org. Chem. , vol.29 , pp. 1105-1114
    • Zeng, C.C.1    Niu, L.T.2    Ping, D.W.3    Zhong, R.G.4
  • 11
    • 0242468157 scopus 로고    scopus 로고
    • Synthesis of styrylbenzofuran derivatives as styrylquinoline analogues for HIV-1 integrase inhibitors
    • Yoo, H.; Lee, J. Y.; Park, J. H.; Chung, B. Y.; Lee, Y. S. Synthesis of styrylbenzofuran derivatives as styrylquinoline analogues for HIV-1 integrase inhibitors. Farmaco 2003, 58, 1243-1250.
    • (2003) Farmaco , vol.58 , pp. 1243-1250
    • Yoo, H.1    Lee, J.Y.2    Park, J.H.3    Chung, B.Y.4    Lee, Y.S.5
  • 12
    • 0000452212 scopus 로고
    • Selectivity in tosylation of o-aminophenol by choice of tertiary amine
    • Kurita, K. Selectivity in tosylation of o-aminophenol by choice of tertiary amine Chem. Ind. 1974, 345-346.
    • (1974) Chem. Ind. , pp. 345-346
    • Kurita, K.1
  • 14
    • 39849087244 scopus 로고    scopus 로고
    • A novel high-throughput format assay for HIV-1 integrase strand transfer reaction using magnetic beads
    • He, H. Q.; Ma, X. H.; Liu, B.; Zhang, X. Y.; Chen, W. Z.; Wang, C. X.; Cheng, S. H. A novel high-throughput format assay for HIV-1 integrase strand transfer reaction using magnetic beads. Acta Pharmacol. Sin. 2008, 29, 397-404.
    • (2008) Acta Pharmacol. Sin. , vol.29 , pp. 397-404
    • He, H.Q.1    Ma, X.H.2    Liu, B.3    Zhang, X.Y.4    Chen, W.Z.5    Wang, C.X.6    Cheng, S.H.7
  • 16
    • 0037674295 scopus 로고
    • Derivatives of 5-chloro-8-hydroxyquinoline
    • Weizmann, M.; Bograchov, E. Derivatives of 5-chloro-8-hydroxyquinoline. J. Am. Chem. Soc. 1947, 69, 1222-1223.
    • (1947) J. Am. Chem. Soc. , vol.69 , pp. 1222-1223
    • Weizmann, M.1    Bograchov, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.