Amitriptyline rather than lornoxicam ameliorates neuropathic pain-induced deficits in abilities of spatial learning and memory

European Journal of Anaesthesiology

Volumn 27, Issue 2, 2010, Pages 162-168

  Hu, Yifeng ^a   Yang, Jianjun ^a   Hu, Yuping ^b   Wang, Yu ^b   Li, Weiyan ^a  

^a JINLING HOSPITAL   (China)

^b Hospital of Xuzhou   (China)

Author keywords

Amitriptyline; Brain derived neurotrophic factor; Depression; Learning and memory; Lornoxicam; Neuropathic pain

Indexed keywords

AMITRIPTYLINE; BRAIN DERIVED NEUROTROPHIC FACTOR; LORNOXICAM; SODIUM CHLORIDE; ANALGESIC AGENT; DRUG DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR CHANGE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DEPRESSION; DOWN REGULATION; DRUG EFFECT; HIPPOCAMPUS; LEARNING DISORDER; MALE; MEMORY DISORDER; NERVE TRANSECTION; NEUROPATHIC PAIN; NONHUMAN; PROTEIN EXPRESSION; RAT; SHAM PROCEDURE; SPATIAL MEMORY; SPINAL ROOT; SPRAGUE DAWLEY RAT; UPREGULATION; ANIMAL; COMPARATIVE STUDY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; MAZE TEST; METABOLISM; NEURALGIA;

AMITRIPTYLINE; ANALGESICS, NON-NARCOTIC; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HIPPOCAMPUS; MALE; MAZE LEARNING; MEMORY DISORDERS; NEURALGIA; PIROXICAM; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77950342158     PISSN: 02650215     EISSN: 13652346     Source Type: Journal    
DOI: 10.1097/EJA.0b013e328331a3d5     Document Type: Article

References (22)

1. Gustorff B, Dorner T, Likar R, et al. Prevalence of self-reported neuropathic pain and impact on quality of life: A prospective representative survey. Acta Anaesthesiol Scand 2008; 52:132-136.
2. Castaneda AE, Tuulio-Henriksson A, Marttunen M, et al. A review on cognitive impairments in depressive and anxiety disorders with a focus on young adults. J Affect Disord 2008; 106:1-27.
3. Finnerup NB, Otto M, McQuay HJ, et al. Algorithm for neuropathic pain treatment: An evidence based proposal. Pain 2005; 118:289-305.
4. Bianchi M, Panerai AE. Effects of lornoxicam, piroxicam, and meloxicam in model of thermal hindpaw hyperalgesia induced by formalin injection in rat tail. Pharmacol Res 2002; 45:101-105.
5. Takahashi M, Kawaguchi M, Shimada K, et al. Systemic meloxicam reduces tactile allodynia development after L5 single spinal nerve injury in rats. Reg Anesth Pain Med 2005; 30:351-355.
6. Binder DK, Scharfman HE. Brain-derived neurotrophic factor. Growth Factors 2004; 22:123-131.
7. Alme MN, Wibrand K, Daqestad G, et al. Chronic fluoxetine treatment induces brain region-specific upregulation of genes associated with BDNFinduced long-term potentiation. Neural Plast 2007; 2007:26496.
8. Duric V, McCarson KE. Persistent pain produces stress-like alterations in hippocampal neurogenesis and gene expression. Pain 2006; 7:544-555.
9. Kim H, Chung JM. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 1992; 50:355-363.
10. Cryan JF, Markou A, Lucki I, et al. Assessing antidepressant activity in rodents: Recent developments and future needs. Trends Pharmacol Sci 2002; 23:238-245.
11. Suzuki T, Amata M, Sakaue G, et al. Experimental neuropathy in mice is associated with delayed behavioral changes related to anxiety and depression. Anesth Analg 2007; 104:1570-1577.
12. Duric V, McCarson KE. Persistent pain produces stress-like alterations in hippocampal neurogenesis and gene expression. J Pain 2006; 7:544-555.
13. Duric V, McCarson KE. Hippocampal neurokinin-1 receptor and brainderived neurotrophic factor gene expression is decreased in rat models of pain and stress. Neuroscience 2005; 133:999-1006.
14. Duric V, McCarson KE. Effects of analgesic or antidepressant drugs on pain- or stress-evoked hippocampal and spinal neurokinin-1 receptor and brain-derived neurotrophic factor gene expression in the rat. J Pharmacol Exp Ther 2006; 319:1235-1243.
15. Duman RS, Heninger GR, Nestler EJ. A molecular and cellular theory of depression. Arch Gen Psychiatry 1997; 54:597-606.
16. Hellweg R, Ziegenhorn A, Heuser I, et al. Serum concentrations of nerve growth factor and brain-derived neurotrophic factor in depressed patients before and after antidepressant treatment. Pharmacopsychiatry 2008; 41:66-71.
17. Kovalchuk Y, Hanse E, Kafitz KW, et al. Postsynaptic induction of BDNFmediated long-term potentiation. Science 2002; 295:1729-1734.
18. Do T, Kerr B, Kuzhikandathil EV. Brain-derived neurotrophic factor regulates the expression of D1 dopamine receptors. J Neurochem 2007; 100:416-428.
19. Lynch ME. Antidepressants as analgesics: A review of randomized controlled trials. J Psychiatry Neurosci 2001; 26:30-36.
20. Benbouzid M, Choucair-Jaafar N, Yalcin I, et al. Chronic, but not acute tricyclic antidepressant treatment alleviates neuropathic allodynia after sciatic nerve cuffing in mice. Eur J Pain 2008; 12:1008-1017.
21. Yau JL, Noble J, Hibberd C, et al. Chronic treatment with the antidepressant amitriptyline prevents impairments in water maze learning in aging rats. J Neurosci 2002; 22:1436-1442.
22. Kontinen VK, Kauppila T, Paananen S, et al. Behavioual measures of depression and anxiety in rats with spinal nerve ligation-induced neuropathy. Pain 1999; 80:341-346.