Synthesis and evaluation of alkenyl indazoles as selective Aurora kinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 8, 2010, Pages 2443-2447

  Blanchard, Stéphanie ^a   William, Anthony D ^a   Lee, Angeline C H ^a   Poulsen, Anders ^a   Teo, Ee Ling ^a   Deng, Weiping ^a   Tu, Noah ^a   Tan, Evelyn ^a   Goh, Kay Lin ^a   Ong, Wai Chung ^a   Ng, Chee Pang ^a   Goh, Kee Chuan ^a   Bonday, Zahid ^a   Sun, Eric T ^a  

^a S BIO Pte Ltd   (Singapore)

Author keywords

Aurora kinase; Indazole; Selectivity

Indexed keywords

AURORA KINASE INHIBITOR; INDAZOLE DERIVATIVE;

ARTICLE; BINDING AFFINITY; DRUG ACTIVITY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION;

DRUG EVALUATION, PRECLINICAL; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES;

EID: 77950299788     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.03.018     Document Type: Article

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