Evidence for the hypothesis that 10-formyldihydrofolate is the in vivo substrate for aminoimidazolecarboxamide ribotide transformylase

Experimental Biology and Medicine

Volumn 235, Issue 3, 2010, Pages 271-277

  Baggott, Joseph E ^a   Tamura, Tsunenobu ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

10 formyldihydrofolate; AICAR transformylase; Folate; In vivo coenzymes; Purine nucleotide biosynthesis

Indexed keywords

10 FORMYL 7,8 DIHYDRIFOLATE; 10 FORMYLDIHYDROFOLATE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; CYTOCHROME C; FOLIC ACID DERIVATIVE; METHOTREXATE; PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE; PURINE DERIVATIVE; UNCLASSIFIED DRUG;

DRUG EXCRETION; DRUG INHIBITION; DRUG SYNTHESIS; ENZYME KINETICS; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; NONHUMAN; RHEUMATOID ARTHRITIS; SHORT SURVEY; URIC ACID BLOOD LEVEL;

ADMINISTRATION, ORAL; ANIMALS; ARTHRITIS, RHEUMATOID; CARBON; CYTOCHROMES C; FOLIC ACID; HUMANS; KINETICS; METHOTREXATE; MITOCHONDRIA; PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE; PURINES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

ANIMALIA; MAMMALIA;

EID: 77950286821     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2009.009151     Document Type: Short Survey

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