Evaluation of folate-PAMAM for the delivery of antisense oligonucleotides to rat C6 glioma cells in vitro and in vivo

Journal of Biomedical Materials Research - Part A

Volumn 93, Issue 2, 2010, Pages 585-594

  Kang, Chunsheng ^a,b   Yuan, Xubo ^c   Li, Fei ^c   Pu, Peiyu ^a,b   Yu, Shizhu ^b   Shen, Changhong ^b   Zhang, Zhiyong ^b   Zhang, Yunting ^b  

^a Tianjin Neurological Institute   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c TIANJIN UNIVERSITY   (China)

Author keywords

Antisense oligonucleotides; Gene delivery; Gliomas; PAMAM dendrimer; Targeting

Indexed keywords

AGAROSE; AMINO GROUP; ANTISENSE OLIGONUCLEOTIDES; DELIVERY SYSTEMS; EPIDERMAL GROWTH FACTOR RECEPTORS; FOLIC ACIDS; GENE DELIVERY; GLIOMA CELLS; IN-SITU; IN-VITRO; PAMAM DENDRIMER; POLYAMIDOAMINE DENDRIMERS; SURVIVAL TIME; TUMOR GROWTH;

CELL GROWTH; DENDRIMERS; ELECTROPHORESIS; FUNCTIONAL POLYMERS; GENE TRANSFER; GROWTH KINETICS; NUCLEIC ACIDS; ORGANIC ACIDS; TUMORS;

OLIGONUCLEOTIDES;

1 [3 (DIMETHYLAMINO)PROPYL] 3 ETHYLCARBODIIMIDE; ANTISENSE OLIGONUCLEOTIDE; CHEMICAL AGENT; DENDRIMER; EPIDERMAL GROWTH FACTOR RECEPTOR; FOLIC ACID; OLIGOFECTAMINE; POLYAMIDOAMINE; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CELL CYCLE PARAMETERS; CELL GROWTH; COMPLEX FORMATION; FEMALE; FLOW CYTOMETRY; GENE TARGETING; GENETIC TRANSFECTION; GLIOMA; GLIOMA CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BIOCOMPATIBLE MATERIALS; CELL CYCLE; CELL LINE, TUMOR; DENDRIMERS; DRUG DELIVERY SYSTEMS; FEMALE; FLOW CYTOMETRY; FOLIC ACID; GENE THERAPY; GLIOMA; HUMANS; MATERIALS TESTING; NEOPLASM TRANSPLANTATION; OLIGONUCLEOTIDES, ANTISENSE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 77950284078     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32525     Document Type: Article

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