Augurin stimulates the hypothalamo-pituitary-adrenal axis via the release of corticotrophin-releasing factor in rats

British Journal of Pharmacology

Volumn 159, Issue 8, 2010, Pages 1663-1671

  Tadross, Ja ^a   Patterson, M ^a   Suzuki, K ^a   Beale, Ke ^a   Boughton, Ck ^a   Smith, Kl ^a   Moore, S ^b   Ghatei, Ma ^a   Bloom, S R ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b Bachem Holding AG   (Switzerland)

Author keywords

Augurin; CRF; Hypothalamo pituitary adrenal axis; Paraventricular nucleus

Indexed keywords

ARGIPRESSIN; AUGURIN; CORTICOSTERONE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; PEPTIDE HORMONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME RELEASE; EX VIVO STUDY; HORMONE BLOOD LEVEL; HORMONE RELEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT;

ANIMALS; BEHAVIOR, ANIMAL; CORTICOTROPIN-RELEASING HORMONE; HORMONES; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INJECTIONS, INTRAVENTRICULAR; MALE; NEOPLASM PROTEINS; PITUITARY-ADRENAL SYSTEM; RATS; RATS, WISTAR;

EID: 77950226277     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00655.x     Document Type: Article

References (24)

1. Abbott CR, Kennedy AR, Wren AM, Rossi M, Murphy KG, Seal LJ et al. (2003). Identification of hypothalamic nuclei involved in the orexigenic effect of melanin-concentrating hormone. Endocrinology 144 : 3943 3949.
2. Alexander SPH, Mathie A, Peters JA (2009). Guide to Receptors and Channels (GRAC), 4th edn. Br J Pharmacol 158 (Suppl. 1 S1 S254.
3. Bewick GA, Dhillo WS, Darch SJ, Murphy KG, Gardiner JV, Jethwa PH et al. (2005). Hypothalamic cocaine- and amphetamine-regulated transcript (CART) and agouti-related protein (AgRP) neurons coexpress the NOP1 receptor and nociceptin alters CART and AgRP release. Endocrinology 146 : 3526 3534.
4. Bland JM, Altman DG (1996). The use of transformation when comparing two means. BMJ 312 : 1153.
5. Buckingham JC (2006). Glucocorticoids: exemplars of multi-tasking. Br J Pharmacology 147 : S258.
6. Dhillo WS, Small CJ, Jethwa PH, Russell SH, Gardiner JV, Bewick GA et al. (2003). Paraventricular nucleus administration of calcitonin gene-related peptide inhibits food intake and stimulates the hypothalamo-pituitary-adrenal axis. Endocrinology 144 : 1420 1425.
7. Fray PJ, Sahakian BJ, Robbins TW, Koob GF, Iversen SD (1980). An observational method for quantifying the behavioural effects of dopamine agonists: contrasting effects of d-amphetamine and apomorphine. Psychopharmacology (Berl) 69 : 253 259.
8. Gulyas J, Rivier C, Perrin M, Koerber SC, Sutton S, Corrigan A et al. (1995). Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor. Proc Natl Acad Sci U S A 92 : 10575 10579.
9. Habib KE, Weld KP, Rice KC, Pushkas J, Champoux M, Listwak S et al. (2000). Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates. Proc Natl Acad Sci U S A 97 : 6079 6084.
10. Herman JP (1997). Neurocircuitry of stress: central control of the hypothalamo-pituitary-adrenocortical axis. Trends Cogn Sci 20 : 78.
11. Kinzig KP, D'Alessio DA, Herman JP, Sakai RR, Vahl TP, Figueiredo HF et al. (2003). CNS glucagon-like peptide-1 receptors mediate endocrine and anxiety responses to interoceptive and psychogenic stressors. J Neurosci 23 : 6163 6170.
12. Mirabeau O, Perlas E, Severini C, Audero E, Gascuel O, Possenti R et al. (2007). Identification of novel peptide hormones in the human proteome by hidden Markov model screening. Genome Res 17 : 320 327.
13. Paxinos G, Watson C (2007). The Rat Brain in Stereotaxic Coordinates. Academic press : San Diego, CA.
14. Rhen T, Cidlowski JA (2005). Antiinflammatory action of glucocorticoids-new mechanisms for old drugs. N Engl J Med 353 : 1711 1723.
15. Roberton A, Gonzalez AM, Stopa E, Leadbeater W, Coimbra R, Johanson C et al. (2009). Immunohistochemical evidence that Argillin, the product of the ECRG4 gene, encodes a novel neuroendocrine peptide. Presented at Society for Endocrinology BES 2009, Harrogate, UK.
16. Rossi M, Choi SJ, O'Shea D, Miyoshi T, Ghatei MA, Bloom SR (1997). Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight. Endocrinology 138 : 351 355.
17. Smith KL, Patterson M, Dhillo WS, Patel SR, Semjonous NM, Gardiner JV et al. (2006). Neuropeptide S stimulates the hypothalamo-pituitary-adrenal axis and inhibits food intake. Endocrinology 147 : 3510 3518.
18. Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D et al. (2004). A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci USA 101 : 6062 6067.
19. Su T, Liu H, Lu S (1998). Cloning and identification of cDNA fragments related to human esophageal cancer. Zhonghua Zhong Liu Za Zhi 20 : 254 257.
20. Watanabe T, Morimoto A, Sakata Y, Wada M, Murakami N (1991). The effect of chronic exercise on the pituitary-adrenocortical response in conscious rats. J Physiol 439 : 691 699.
21. Whitnall MH (1993). Regulation of the hypothalamic corticotropin- releasing hormone neurosecretory system. Prog Neurobiol 40 : 573 629.
22. Wren AM, Small CJ, Abbott CR, Jethwa PH, Kennedy AR, Murphy KG et al. (2002). Hypothalamic actions of neuromedin U. Endocrinology 143 : 4227 4234.
23. Yue CM, Deng DJ, Bi MX, Guo LP, Lu SH (2003). Expression of ECRG4, a novel esophageal cancer-related gene, downregulated by CpG island hypermethylation in human esophageal squamous cell carcinoma. World J Gastroenterol 9 : 1174 1178.
24. Zoumakis E, Grammatopoulos DK, Chrousos GP (2006). Corticotropin- releasing hormone receptor antagonists. Eur J Endocrinol 155 : S85.