Distribution and expression pattern of claudins 6, 7, and 9 in diffuse- and intestinal-type gastric adenocarcinomas

Journal of Gastrointestinal Cancer

Volumn 41, Issue 1, 2010, Pages 52-59

  Rendón Huerta, Erika ^a   Teresa, Fortoul ^a   Teresa, Gorráez María ^b   Xochitl, Garcia Samper ^b   Georgina, Alvarez Fernández ^a   Veronica, Zavala Zendejas ^a   Montaño, Luis Felipe ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b CENTRO MÉDICO NACIONAL 20 DE NOVIEMBRE   (Mexico)

Author keywords

Claudins; Diffuse type gastric adenocarcinoma; Gastric carcinogenesis; Intestinal type gastric adenocarcinoma; Tight junction proteins

Indexed keywords

CLAUDIN 6; CLAUDIN 7; CLAUDIN 9; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; TUMOR MARKER; UNCLASSIFIED DRUG;

AGED; APICAL MEMBRANE; ARTICLE; CANCER DIAGNOSIS; CANCER MORTALITY; CELL FRACTIONATION; CELL LYSATE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE MARKER; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE CARCINOMA; INTESTINE CELL; MALE; PATIENT ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STOMACH ADENOCARCINOMA; STOMACH BIOPSY; STOMACH CANCER; SURVIVAL RATE; WESTERN BLOTTING;

EID: 77950188724     PISSN: 19416628     EISSN: 19416636     Source Type: Journal    
DOI: 10.1007/s12029-009-9110-y     Document Type: Article

References (54)

1. L Gonzalez-Mariscal A Betanzos P Nava BE Jaramillo 2003 Tight junction proteins Prog Biophys Mol Biol 81 1 44 10.1016/S0079-6107(02)00037-8 1:CAS:528:DC%2BD38XptlSqtLc%3D 12475568 (Pubitemid 35436609)
2. RS Weinstein FB Merk J Alroy 1976 The structure and function of intercellular junctions in cancer Adv Cancer Res 23 23 89 10.1016/S0065-230X(08) 60543-6 1:CAS:528:DyaE28XkvFWms78%3D 179291
3. K Morita M Furuse K Fujimoto S Tsukita 1999 Claudin multigene family encoding four transmembrane domain protein components of tight junction strands Proc Natl Acad Sci USA 96 511 6 10.1073/pnas.96.2.511 1:CAS:528: DyaK1MXmtlCmsw%3D%3D 9892664 (Pubitemid 29061239)
4. M Furuse K Furuse H Sasaki S Tsukita 2001 Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells J Cell Biol 153 263 72 10.1083/jcb.153.2.263 1:CAS:528:DC%2BD3MXivFOiuro%3D 11309408 (Pubitemid 34280213)
5. L Gonzalez-Mariscal R Tapia D Chamorro 2008 Crosstalk of tight junction components with signalling pathways Biochim Biophys Acta 1778 729 56 10.1016/j.bbamem.2007.08.018 1:CAS:528:DC%2BD1cXjtVSqtL4%3D 17950242
6. JM Mullin KV Laughlin N Ginanni CW Marano HM Clarke A Peralta Soler 2000 Increased tight junction permeability can result from protein kinase C activation/translocation and act as a tumor promotional event in epithelial cancers Ann N Y Acad Sci 915 231 6 1:CAS:528:DC%2BD3MXntVCntA%3D%3D 11193580
7. E Rendon-Huerta MC Valenzano JM Mullin, et al. 2003 Comparison of three integral tight junction barrier proteins in Barrett's epithelium versus normal esophageal epithelium Am J Gastroenterol 98 1901 3 10.1111/j.1572-0241.2003. 07607.x 12907361 (Pubitemid 36959184)
8. M Katoh 2005 Epithelial-mesenchymal transition in gastric cancer Int J Oncol 27 1677 83 1:CAS:528:DC%2BD2MXhtlSru7rI 16273224
9. W Yasui K Sentani J Motoshita H Nakayama 2006 Molecular pathobiology of gastric cancer Scand J Surg 95 225 31 1:STN:280:DC%2BD2s%2Fks1Omtg%3D%3D 17249269
10. DM Roder 2002 The epidemiology of gastric cancer Gastric Cancer 5 Suppl 1 5 11 10.1007/s10120-002-0203-6 12772880 (Pubitemid 36604663)
11. Y Soini S Tommola H Helin P Martikainen 2006 Claudins 1, 3, 4 and 5 in gastric carcinoma, loss of claudin expression associates with the diffuse subtype Virchows Arch 448 52 8 10.1007/s00428-005-0011-6 1:CAS:528: DC%2BD28XhtVajsb4%3D 16220299 (Pubitemid 43177415)
12. MB Resnick M Gavilanez E Newton, et al. 2005 Claudin expression in gastric adenocarcinomas: a tissue microarray study with prognostic correlation Hum Pathol 36 886 92 10.1016/j.humpath.2005.05.019 1:CAS:528: DC%2BD2MXos1Wqtrc%3D 16112005 (Pubitemid 41187907)
13. WL Kuo LY Lee CM Wu, et al. 2006 Differential expression of claudin-4 between intestinal and diffuse-type gastric cancer Oncol Rep 16 729 34 1:CAS:528:DC%2BD28XhtFSisrzK 16969486
14. SC Cunningham F Kamangar MP Kim, et al. 2006 Claudin-4, mitogen-activated protein kinase kinase 4, and stratifin are markers of gastric adenocarcinoma precursor lesions Cancer Epidemiol Biomarkers Prev 15 281 7 10.1158/1055-9965. EPI-05-0539 1:CAS:528:DC%2BD28Xhs1Wrsbc%3D 16492916 (Pubitemid 43342175)
15. Y Matsuda S Semba J Ueda, et al. 2007 Gastric and intestinal claudin expression at the invasive front of gastric carcinoma Cancer Sci 98 1014 9 10.1111/j.1349-7006.2007.00490.x 1:CAS:528:DC%2BD2sXnsVOqsrc%3D 17459057 (Pubitemid 46865385)
16. K Turksen TC Troy 2002 Permeability barrier dysfunction in transgenic mice overexpressing claudin 6 Development 129 1775 84 1:CAS:528: DC%2BD38Xjt1eit7c%3D 11923212
17. AH Johnson HF Frierson A Zaika, et al. 2005 Expression of tight-junction protein claudin-7 is an early event in gastric tumorigenesis Am J Pathol 167 577 84 1:CAS:528:DC%2BD2MXpsVeqt70%3D 16049341
18. JY Park KH Park TY Oh, et al. 2007 Up-regulated claudin 7 expression in intestinal type gastric carcinoma Oncol Rep 18 377 82 1:CAS:528: DC%2BD2sXpsFGltL8%3D 17611659
19. NGM Padera GI TP T Shioda RK Jain 2007 Differential gene expression of primary cultured lymphatic and blood vascular endothelial cells Neoplasia 9 1038 45 10.1593/neo.07643 18084611 (Pubitemid 350255352)
20. A Zheng F Yuan LI Yanqin, et al. 2007 Claudin-6 and Claudin-9 Function as additional coreceptors for Hepatitis C Virus J Virol 81 12465 71 10.1128/JVI.01457-07 1:CAS:528:DC%2BD2sXhtlKku7zI 17804490 (Pubitemid 350085860)
21. L Meertens C Bertaux L Cukierman, et al. 2008 The tight junction proteins claudin-1, -6 and -9 are entry cofactors for the Hepatitis C virus J Virol 82 3555 60 10.1128/JVI.01977-07 1:CAS:528:DC%2BD1cXjvFensbY%3D 18234789
22. G Abuazza A Becker SS Williams, et al. 2006 Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins Am J Physiol Renal Physiol 29 F1132 41 10.1152/ajprenal.00063.2006
23. T Tsukamoto T Yokoi S Maruta, et al. 2007 Gastric adenocarcinoma with chief cell differentiation Pathol Int 57 517 22 10.1111/j.1440-1827.2007.02134.x 17610477 (Pubitemid 47030137)
24. P Lauren 1965 The two histological main types of gastric carcinoma: diffuse and so called intestinal-type carcinoma. An attempt at a histo-clinical classification Acta Pathol Microbiol Scand 64 31 49 1:STN:280: DyaF2M7isFenug%3D%3D 14320675
25. JM Mullin AP Soler KV Laughlin, et al. 1996 Chronic exposure of LLC-PK1 epithelia to the phorbol ester TPA produces polyp-like foci with leaky tight junction and altered protein kinase C-alpha expression and localization Exp Cell Res 227 12 22 10.1006/excr.1996.0244 1:CAS:528:DyaK28XltlymtL8%3D 8806446 (Pubitemid 26293410)
26. S Hirohashi Y Kanal 2003 Cell adhesion system and human cancer morphogenesis Cancer Sci 94 575 81 10.1111/j.1349-7006.2003.tb01485.x 1:CAS:528:DC%2BD2cXhs1Kgs7Y%3D 12841864 (Pubitemid 36975010)
27. PJ Morin 2005 Claudin proteins in human cancer: promising new targets for diagnosis and therapy Cancer Res 65 9603 6 10.1158/0008-5472.CAN-05-2782 1:CAS:528:DC%2BD2MXhtFKkt7vL 16266975 (Pubitemid 41541431)
28. M Swisshelm R Macek M Kubbies 2005 Role of claudins in tumorigenesis Adv Drug Deliv Rev 57 919 28 10.1016/j.addr.2005.01.006 1:CAS:528: DC%2BD2MXivFKhsLc%3D 15820559 (Pubitemid 40488110)
29. C Rahner LL Mitic JM Anderson 2001 Heterogeneity in expression and subcellular localization of claudins 2, 3, 4 and 5 in the rat liver, pancreas and gut Gastroenterology 120 411 22 10.1053/gast.2001.21736 1:CAS:528: DC%2BD3MXhtlKltLs%3D 11159882
30. Y Soini 2005 Expression of claudins 1, 2, 3, 4, 5 and 7 in various types of tumors Histopathology 46 551 60 10.1111/j.1365-2559.2005.02127.x 1:STN:280:DC%2BD2M3gvVyltQ%3D%3D 15842637 (Pubitemid 40632312)
31. MB Resnick T Konkin J Routhier E Sabo VE Pricolo 2005 Claudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study Mod Pathol 18 511 8 10.1038/modpathol.3800301 1:CAS:528: DC%2BD2MXisVSht7Y%3D 15475928 (Pubitemid 40478114)
32. JC Machado P Soares F Carneiro, et al. 1999 E-cadherin gene mutations provide a genetic basis for the phenotypic divergence of mixed gastric carcinomas Lab Invest 79 459 65 1:CAS:528:DyaK1MXivVGku7o%3D 10211998
33. LY Lee CM Wu CC Wang, et al. 2008 Expression of matrix metalloproteinases MMP-2 and MMP-9 in gastric cancer and their relation to claudin-4 expression Histol Histopathol 23 515 21 18283635
34. R Witzgall N Obermuller U Bolitz, et al. 1998 Kid-1 expression is high in differentiated renal proximal tubule cells and suppressed in cyst epithelia Am J Physiol 275 F928 37 1:CAS:528:DyaK1MXht1yjtA%3D%3D 9843910
35. M Oyamada VA Krutovskikh M Mesnil C Partensky F Berger H Yamasaki 1990 Aberrant expression of gap junction gene in primary human hepatocellular carcinomas: increased expression of cardiac-type gap junction gene connexin 43 Mol Carcinog 3 273 8 10.1002/mc.2940030507 1:CAS:528:DyaK3MXhvVejtrY%3D 2173931
36. H Kubota H Chiba Y Takakuwa, et al. 2001 Retinoid X receptor alpha and retinoic acid receptor gamma mediate expression of genes encoding tight-junction proteins and barrier function in F9 cells during visceral endodermal differentiation Exp Cell Res 263 163 72 10.1006/excr.2000.5113 1:CAS:528:DC%2BD3MXlsVSqsg%3D%3D 11161715 (Pubitemid 32989116)
37. O Lefebvre M-P Chenard R Masson, et al. 1996 Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein Science 274 259 62 10.1126/science.274.5285.259 1:CAS:528:DyaK28XmtlWltrY%3D 8824193 (Pubitemid 26353205)
38. JY Zheng D Yu M Foroohar, et al. 2003 Regulation of the expression of the prostate-specific antigen by claudin-7 J Membr Biol 194 187 97 10.1007/s00232-003-2038-4 1:CAS:528:DC%2BD3sXntlalurw%3D 14502431 (Pubitemid 37013811)
39. Y Ban A Dota LJ Cooper, et al. 2003 Tight junction-related protein expression and distribution in human corneal epithelium Exp Eye Res 76 663 9 10.1016/S0014-4835(03)00054-X 1:CAS:528:DC%2BD3sXjs1eqtL8%3D 12742348 (Pubitemid 36549023)
40. JL Holmes CM Van Itallie JE Rasmussen JM Anderson 2006 Claudin profiling in the mouse during postnatal intestinal development and along the gastrointestinal tract reveals complex expression patterns Gene Expr Patterns 6 581 8 10.1016/j.modgep.2005.12.001 1:CAS:528:DC%2BD28XkvVyhtrs%3D 16458081 (Pubitemid 43758645)
41. M Naumann JE Crabtree 2004 Helicobacter pylori-induced epithelial cell signalling in gastric carcinogenesis Trends Microbiol 12 29 36 10.1016/j.tim.2003.11.005 1:CAS:528:DC%2BD3sXhtVWjtLnK 14700549 (Pubitemid 38045257)
42. Y Chen Q Lu EE Schneeberger DA Goodenough 2000 Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells Mol Biol Cell 11 849 62 1:CAS:528:DC%2BD3cXjslCjurc%3D 10712504
43. T Kinugasa T Sakaguchi X Gu HC Reinecker 2000 Claudins regulate the intestinal barrier in response to immune mediators Gastroenterology 118 1001 11 10.1016/S0016-5085(00)70351-9 1:CAS:528:DC%2BD3cXktlaitbY%3D 10833473
44. Q Li Q Zhang M Wang, et al. 2008 Interferon and tumor necrosis factor disrupt epithelial barrier function by altering lipid composition in membrane microdomains of tight junction Clin Immunol 126 67 80 10.1016/j.clim.2007.08.017 1:CAS:528:DC%2BD2sXhsVOlsL%2FM 17964857 (Pubitemid 350266450)
45. MP Fink 2003 Intestinal epithelial hyperpermeability: update on the pathogenesis of gut mucosal barrier dysfunction in critical illness Curr Opin Crit Care 9 143 51 10.1097/00075198-200304000-00011 12657978 (Pubitemid 36408134)
46. N Murata-Kamiya Y Kurashima Y Teishikata, et al. 2007 Helicobacter pylori CagA interacts with E-cadherin and deregulates the beta-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells Oncogene 26 4617 26 10.1038/sj.onc.1210251 1:CAS:528:DC%2BD2sXnsFOisr8%3D 17237808 (Pubitemid 47067401)
47. R Rad A Dossumbekova B Neu, et al. 2004 Cytokine gene polymorphisms influence mucosal cytokine expression, gastric inflammation, and host specific colonisation during Helycobacter pylori infection Gut 53 1082 9 10.1136/gut.2003.029736 1:CAS:528:DC%2BD2cXmvVehtLo%3D 15247172 (Pubitemid 38961959)
48. KJ Hewitt R Agarwall PJ Morin 2006 The claudin gene family: expression in normal and neoplastic tissues BMC Cancer 6 186 93 10.1186/1471-2407-6-186 16836752 (Pubitemid 46277109)
49. JP Fedwick TK Lapointe JB Meddings PM Sherman AG Buret 2005 Helicobacter pylori activates myosin light-chain kinase to disrupt claudin-4 and claudin-5 and increase epithelial permeability Infect Immun 73 7844 52 10.1128/IAI.73.12.7844-7852.2005 1:CAS:528:DC%2BD2MXhtlersbjE 16299274 (Pubitemid 41740267)
50. HR Higashi S Tsutsumi T Muto, et al. 2002 SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein Science 295 683 6 10.1126/science.1067147 1:CAS:528:DC%2BD38XptF2rsQ%3D%3D 11743164 (Pubitemid 34111828)
51. P Michl M Buchholz M Rolke, et al. 2001 Claudin-4: a new target for pancreatic cancer treatment using Clostridium perfringens enterotoxin Gastroenterology 121 678 84 10.1053/gast.2001.27124 1:CAS:528: DC%2BD3MXntVKnsbc%3D 11522752
52. C Rahner M Fukuhara S Peng S Kijima LJ Rizzolo 2004 The apical and basal environments of the retinal pigment epithelium regulate the maturation of tight junctions during development J Cell Sci 117 3307 18 10.1242/jcs.01181 1:CAS:528:DC%2BD2cXms1ensLg%3D 15226402 (Pubitemid 39139915)
53. J Matsubara Y Yamada Y Hirashima, et al. 2008 Impact of insulin-like growth factor type 1 receptor, epidermal growth factor receptor, and HER2 expressions on outcomes of patients with gastric cancer Clin Cancer Res 14 3022 9 10.1158/1078-0432.CCR-07-1898 1:CAS:528:DC%2BD1cXmtVCmtLc%3D 18483367
54. YY Chou YM Jeng TT Lee, et al. 2007 Cytoplasmic CD24 expression is a novel prognostic factor in diffusse-type gastric adenocarcinoma Ann Surg Oncol 14 2748 58 17680316