Interferon-γ and tumor necrosis factor-α disrupt epithelial barrier function by altering lipid composition in membrane microdomains of tight junction

Clinical Immunology

Volumn 126, Issue 1, 2008, Pages 67-80

  Li, Qiurong ^a   Zhang, Qiang ^a   Wang, Meng ^a,c   Zhao, Sumin ^b   Ma, Jian ^a   Luo, Nan ^a   Li, Ning ^a   Li, Yousheng ^a   Xu, Guowang ^b   Li, Jieshou ^a  

^a JINLING HOSPITAL   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c NANJING UNIVERSITY   (China)

Author keywords

Barrier function; ; Fatty acid composition; ; Membrane microdomains; ; Phospholipids; ; Tight junction proteins; Tight junction;

Indexed keywords

CLAUDIN; CYTOKINE; DETERGENT; FLOTILLIN 1; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GAMMA INTERFERON; PHOSPHOLIPID; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CROHN DISEASE; ENTEROPATHY; HUMAN; HUMAN CELL; INFLAMMATION; INTESTINE EPITHELIUM; LIPID COMPOSITION; MEMBRANE FLUIDITY; MEMBRANE PERMEABILITY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TIGHT JUNCTION;

APOPTOSIS; CELL MEMBRANE PERMEABILITY; EPITHELIAL CELLS; FATTY ACIDS; HUMANS; INTERFERON TYPE II; MEMBRANE FLUIDITY; MEMBRANE LIPIDS; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON, TRANSMISSION; PHOSPHOLIPIDS; TIGHT JUNCTIONS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 37249041066     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2007.08.017     Document Type: Article

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