Multi-wavelength spatial LED illumination based detector for in vitro detection of botulinum neurotoxin A activity

Sensors and Actuators, B: Chemical

Volumn 146, Issue 1, 2010, Pages 297-306

  Sun, Steven ^a,b   Francis, Jesse ^b   Sapsford, Kim E ^a   Kostov, Yordan ^b   Rasooly, Avraham ^a,c  

^a Engineering Laboratories   (United States)

^b UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Biodetection; Botulinum neurotoxin A; CCD; Electroluminescent excitation; Fluorescence; F rster Resonance Energy Transfer (FRET); LED

Indexed keywords

ACTIVITY ANALYSIS; ACTIVITY DETECTION; BIO-SECURITY; BIODETECTION; BLUE LEDS; BOTULINUM NEUROTOXIN A; BOTULINUM NEUROTOXINS; CCD DETECTORS; CLEAVAGE SITES; ELECTRO-LUMINESCENT; EXPOSURE TIME; FLUORESCENCE EXCITATION; FOOD SAFETY; HIGH INTENSITY; IN-VITRO; LED ILLUMINATION; LIGHT CHAIN; LIGHT INTENSITY; LIMIT OF DETECTION; LIMITS OF QUANTITATIONS; MULTIWAVELENGTH; OPTICAL DETECTION; PEPTIDE SUBSTRATES; RAPID DETECTION SYSTEMS; RESONANCE ENERGY TRANSFER; SPATIAL LIGHT; WHITE LED;

ASSAYS; DIGITAL CAMERAS; ELECTROLUMINESCENCE; ENERGY TRANSFER; FLUORESCENCE; HEALTH; LIGHT EMITTING DIODES; PEPTIDES; RESONANCE;

DETECTORS;

EID: 77949917393     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.snb.2010.02.009     Document Type: Article

References (50)

1. Peruski A.H., Johnson III L.H., and Peruski Jr. L.F. Rapid and sensitive detection of biological warfare agents using time-resolved fluorescence assays. J. Immunol. Methods 263 (2002) 35-41
2. Sharma S.K., Ferreira J.L., Eblen B.S., and Whiting R.C. Detection of type A, B, E, and F Clostridium botulinum neurotoxins in foods by using an amplified enzyme-linked immunosorbent assay with digoxigenin-labeled antibodies. Appl. Environ. Microbiol. 72 (2006) 1231-1238
3. Keller J.E., Nowakowski J.L., Filbert M.G., and Adler M. Rapid microplate assay for monitoring botulinum neurotoxin B catalytic activity. J. Appl. Toxicol. 19 Suppl. 1 (1999) S13-S17
4. Han S.M., Cho J.H., Cho I.H., et al. Plastic enzyme-linked immunosorbent assays (ELISA)-on-a-chip biosensor for botulinum neurotoxin A. Anal. Chim. Acta 587 (2007) 1-8
5. Guglielmo-Viret V., Attree O., Blanco-Gros V., and Thullier P. Comparison of electrochemiluminescence assay and ELISA for the detection of Clostridium botulinum type B neurotoxin. J. Immunol. Methods 301 (2005) 164-172
6. Ferreira J.L., Eliasberg S.J., Edmonds P., and Harrison M.A. Comparison of the mouse bioassay and enzyme-linked immunosorbent assay procedures for the detection of type A botulinal toxin in food. J. Food Prot. 67 (2004) 203-206
7. Gessler F., Pagel-Wieder S., Avondet M.A., and Bohnel H. Evaluation of lateral flow assays for the detection of botulinum neurotoxin type A and their application in laboratory diagnosis of botulism. Diagn. Microbiol. Infect. Dis. 57 (2007) 243-249
8. Sharma S.K., Eblen B.S., Bull R.L., Burr D.H., and Whiting R.C. Evaluation of lateral-flow Clostridium botulinum neurotoxin detection kits for food analysis. Appl. Environ. Microbiol. 71 (2005) 3935-3941
9. Gessler F., Hampe K., Schmidt M., and Bohnel H. Immunomagnetic beads assay for the detection of botulinum neurotoxin types C and D. Diagn. Microbiol. Infect. Dis. 56 (2006) 225-232
10. Rivera V.R., Gamez F.J., Keener W.K., White J.A., and Poli M.A. Rapid detection of Clostridium botulinum toxins A, B, E, and F in clinical samples, selected food matrices, and buffer using paramagnetic bead-based electrochemiluminescence detection. Anal. Biochem. 353 (2006) 248-256
11. Gessler F., Hampe K., and Bohnel H. Sensitive detection of botulinum neurotoxin types C and D with an immunoaffinity chromatographic column test. Appl. Environ. Microbiol. 71 (2005) 7897-7903
12. Attree O., Guglielmo-Viret V., Gros V., and Thullier P. Development and comparison of two immunoassay formats for rapid detection of botulinum neurotoxin type A. J. Immunol. Methods 325 (2007) 78-87
13. Golden J., Shriver-Lake L., Sapsford K., and Ligler F. A "do-it-yourself" array biosensor. Methods 37 (2005) 65-72
14. Ligler F.S., Sapsford K.E., Golden J.P., et al. The array biosensor: portable, automated systems. Anal. Sci. 23 (2007) 5-10
15. Ligler F.S., Taitt C.R., Shriver-Lake L.C., Sapsford K.E., Shubin Y., and Golden J.P. Array biosensor for detection of toxins. Anal. Bioanal. Chem. 377 (2003) 469-477
16. Phillips R.W., and Abbott D. High-throughput enzyme-linked immunoabsorbant assay (ELISA) electrochemiluminescent detection of botulinum toxins in foods for food safety and defence purposes. Food Addit. Contam. 25 (2008) 1084-1088
17. Ganapathy R., Padmanabhan S., Eric Y.P., Moochhala S., Lionel L.K., and Ponnampalam G. Rapid detection of botulinum neurotoxins A, B, E, and F by optical immunoassay. Front. Biosci. 13 (2008) 5432-5440
18. Volland H., Lamourette P., Nevers M.C., et al. A sensitive sandwich enzyme immunoassay for free or complexed Clostridium botulinum neurotoxin type A. J. Immunol. Methods 330 (2008) 120-129
19. Chiao D.J., Wey J.J., Shyu R.H., and Tang S.S. Monoclonal antibody-based lateral flow assay for detection of botulinum neurotoxin type A. Hybridoma (2005) 27 (2008) 31-35
20. CDC. Botulism in the United States 1899-1996: Handbook for Epidemiologists, Clinicians, and Laboratory Workers (1998), Centers for Disease Control and Prevention, Atlanta, GA
21. Nowakowski A., Wang C., Powers D.B., et al. Potent neutralization of botulinum neurotoxin by recombinant oligoclonal antibody. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 11346-11350
22. Keller J.E. Recovery from botulinum neurotoxin poisoning in vivo. Neuroscience (2006)
23. Schantz E.J., and Johnson E.A. Dose standardisation of botulinum toxin. Lancet 335 (1990) 421
24. Schantz E.J., and Johnson E.A. Properties and use of botulinum toxin and other microbial neurotoxins in medicine. Microbiol. Rev. 56 (1992) 80-99
25. Shone C.C., Quinn C.P., Wait R., Hallis B., Fooks S.G., and Hambleton P. Proteolytic cleavage of synthetic fragments of vesicle-associated membrane protein, isoform-2 by botulinum type B neurotoxin. Eur. J. Biochem. 217 (1993) 965-971
26. Schiavo G., Benfenati F., Poulain B., et al. Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin. Nature 359 (1992) 832-835
27. Schiavo G., Poulain B., Rossetto O., Benfenati F., Tauc L., and Montecucco C. Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc. Embo J. 11 (1992) 3577-3583
28. Sudhof T.C., De Camilli P., Niemann H., and Jahn R. Membrane fusion machinery: insights from synaptic proteins. Cell 75 (1993) 1-4
29. Blasi J., Chapman E.R., Link E., et al. Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25. Nature 365 (1993) 160-163
30. Schiavo G., Rossetto O., Catsicas S., et al. Identification of the nerve terminal targets of botulinum neurotoxin serotypes A, D, and E. J. Biol. Chem. 268 (1993) 23784-23787
31. Trimble W.S. Analysis of the structure and expression of the VAMP family of synaptic vesicle proteins. J. Physiol. Paris 87 (1993) 107-115
32. Dong M., Tepp W.H., Johnson E.A., and Chapman E.R. Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 14701-14706
33. Kalb S.R., Moura H., Boyer A.E., McWilliams L.G., Pirkle J.L., and Barr J.R. The use of Endopep-MS for the detection of botulinum toxins A, B, E, and F in serum and stool samples. Anal. Biochem. 351 (2006) 84-92
34. Rasooly R., Stanker L.H., Carter J.M., et al. Detection of botulinum neurotoxin-A activity in food by peptide cleavage assay. Int. J. Food Microbiol. 126 (2008) 135-139
35. Rasooly R., and Do P.M. Development of an in vitro activity assay as an alternative to the mouse bioassay for Clostridium botulinum neurotoxin type A. Appl. Environ. Microbiol. 74 (2008) 4309-4313
36. Jones R.G., Liu Y., and Sesardic D. New highly specific botulinum type C1 endopeptidase immunoassays utilising SNAP25 or Syntaxin substrates. J. Immunol. Methods (2009)
37. Kegel B., Behrensdorf-Nicol H.A., Bonifas U., et al. An in vitro assay for detection of tetanus neurotoxin activity: using antibodies for recognizing the proteolytically generated cleavage product. Toxicol. In Vitro 21 (2007) 1641-1649
38. Jones R.G., Ochiai M., Liu Y., Ekong T., and Sesardic D. Development of improved SNAP25 endopeptidase immuno-assays for botulinum type A and E toxins. J. Immunol. Methods 329 (2008) 92-101
39. Boldt G.E., Kennedy J.P., Hixon M.S., et al. Synthesis, characterization and development of a high-throughput methodology for the discovery of botulinum neurotoxin a inhibitors. J. Combinatorial Chem. 8 (2006) 513-521
40. Perpetuo E.A., Juliano L., Juliano M.A., et al. Enzymatic profiling of tetanus and botulinum neurotoxins based on vesicle-associated-membrane protein derived fluorogenic substrates. Protein Peptide Lett. 15 (2008) 1100-1106
41. Pires-Alves M., Ho M., Aberle K.K., Janda K.D., and Wilson B.A. Tandem fluorescent proteins as enhanced FRET-based substrates for botulinum neurotoxin activity. Toxicon 53 (2009) 392-399
42. Hines H.B., Kim A.D., Stafford R.G., et al. Use of a recombinant fluorescent substrate with cleavage sites for all botulinum neurotoxins in high-throughput screening of natural product extracts for inhibitors of serotypes A, B, and E. Appl. Environ. Microbiol. 74 (2008) 653-659
43. Bagramyan K., Barash J.R., Arnon S.S., and Kalkum M. Attomolar detection of botulinum toxin type A in complex biological matrices. PLoS ONE 3 (2008) e2041
44. Frisk M.L., Berthier E., Tepp W.H., Johnson E.A., and Beebe D.J. Bead-based microfluidic toxin sensor integrating evaporative signal amplification. Lab Chip 8 (2008) 1793-1800
45. Mangru S., Bentz B.L., Davis T.J., et al. Integrated bioassays in microfluidic devices: botulinum toxin assays. J. Biomol. Screen. 10 (2005) 788-794
46. Sapsford K.E., Sun S., Francis J., Sharma S., Kostov Y., and Rasooly A. A fluorescence detection platform using spatial electroluminescent excitation for measuring botulinum neurotoxin A activity. Biosens. Bioelectron. 24 (2008) 618-625
47. Sapsford K.E., Sun S., Francis J., Sharma S., Kostov Y., and Rasooly A. A fluorescence detection platform using spatial electroluminescent excitation for measuring botulinum neurotoxin A activity. Biosens. Bioelectron. (2008)
48. Sapsford K.E., Francis J., Sun S., Kostov Y., and Rasooly A. Miniaturized 96-well ELISA chips for staphylococcal enterotoxin B detection using portable colorimetric detector. Anal. Bioanal. Chem. (2009)
49. Schmidt J.J., and Stafford R.G. Fluorigenic substrates for the protease activities of botulinum neurotoxins, serotypes A, B, and F. Appl. Environ. Microbiol. 69 (2003) 297-303
50. Sapsford K.E., Taitt C.R., Loo N., and Ligler F.S. Biosensor detection of botulinum toxoid A and staphylococcal enterotoxin B in food. Appl. Environ. Microbiol. 71 (2005) 5590-5592