An in vitro assay for detection of tetanus neurotoxin activity: Using antibodies for recognizing the proteolytically generated cleavage product

Toxicology in Vitro

Volumn 21, Issue 8, 2007, Pages 1641-1649

  Kegel, B ^a   Behrensdorf Nicol, H A ^a   Bonifas, U ^a   Silberbach, K ^a   Klimek, J ^a   Kramer B ^a   Weisser K ^a  

^a PAUL EHRLICH INSTITUT   (Germany)

Author keywords

Botulinum neurotoxin type B; Cleavage site specific antibody; ELISA; Endopeptidase assay; Synaptobrevin 2; Tetanus neurotoxin; Vesicle associated membrane protein

Indexed keywords

BOTULINUM TOXIN; NEUROTOXIN; POLYCLONAL ANTIBODY; PROTEINASE; RECOMBINANT PROTEIN; SYNAPTOBREVIN 2; TETANUS TOXIN;

ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; DRUG SAFETY; ENZYME ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; MICROTITER PLATE ASSAY; NONHUMAN; PROTEIN DEGRADATION; PROTEIN IMMOBILIZATION; SENSITIVITY ANALYSIS; TOXIN ANALYSIS;

AMINO ACID SEQUENCE; ANTIBODIES; BOTULINUM TOXINS; ENDOPEPTIDASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; ENZYMES, IMMOBILIZED; METALLOENDOPEPTIDASES; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; TETANUS TOXIN; VESICLE-ASSOCIATED MEMBRANE PROTEIN 2;

BACTERIA (MICROORGANISMS);

EID: 36049037645     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.06.015     Document Type: Article

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