Carotid artery calcification on CT may independently predict stroke risk

American Journal of Roentgenology

Volumn 186, Issue 2, 2006, Pages 547-552

  Nandalur, Kiran R ^a   Baskurt, Erol ^a   Hagspiel, Klaus D ^a   Finch, Michael ^a   Phillips, C Douglas ^a   Bollampally, Sirisha R ^b   Kramer, Christopher M ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b WILLIAM BEAUMONT HOSPITAL   (United States)

Author keywords

Calcium; Carotid; CT arteriography; Stroke

Indexed keywords

CALCIUM;

ADULT; AGED; ARTERY CALCIFICATION; ARTICLE; BRAIN ATHEROSCLEROSIS; BRAIN ISCHEMIA; CARDIOVASCULAR RISK; CAROTID ARTERY OBSTRUCTION; CAROTID ENDARTERECTOMY; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; DIAGNOSTIC ACCURACY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIDETECTOR COMPUTED TOMOGRAPHY; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; RISK ASSESSMENT; STROKE; CALCINOSIS; CEREBROVASCULAR ACCIDENT; COMPUTER ASSISTED TOMOGRAPHY; METHODOLOGY; PREDICTION AND FORECASTING; RADIOGRAPHY; RETROSPECTIVE STUDY; RISK FACTOR; STATISTICAL MODEL;

AGED; CALCINOSIS; CAROTID STENOSIS; CEREBROVASCULAR ACCIDENT; FEMALE; HUMANS; LOGISTIC MODELS; MALE; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 33644985575     PISSN: 0361803X     EISSN: None     Source Type: Journal    
DOI: 10.2214/AJR.04.1216     Document Type: Article

References (31)

1. O'Rourke RA, Brundage BH, Froelicher VF, et al. American College of Cardiology/American Heart Association Expert Consensus document on electron-beam computed tomography for the diagnosis and prognosis of coronary artery disease. Circulation 2000; 102:126-140
2. Sangiorgi G, Rumberger JA, Severson A, et al. Arterial calcification and not lumen stenosis is highly correlated with atherosclerotic plaque burden in humans: a histologic study of 723 coronary artery segments using nondecalcifying methodology. J Am Coll Cardiol 1998; 31:126-133
3. Shaw LJ, Raggi P, Schisterman E, Berman DS, Callister TQ. Prognostic value of cardiac risk factors and coronary artery calcium screening for all-cause mortality. Radiology 2003; 28:826-833
4. Kondos GT, Hoff JA, Sevrukov A, et al. Electron-beam tomography coronary artery calcium and cardiac events: a 37-month follow-up of 5635 initially asymptomatic low- to intermediate-risk adults. Circulation 2003; 107:2571-2576
5. Wilson PW, Kauppila LI, O'Donnell CJ, et al. Abdominal aortic calcific deposits are an important predictor of vascular morbidity and mortality. Circulation 2001; 103:1529-1534
6. Iribarren C, Sidney S, Sternfeld B, Browner WS. Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. JAMA 2000; 283:2810-2815
7. Culebras A, Otero C, Toledo JR, Rubin BS. Computed tomographic study of cervical carotid calcification. Stroke 1989; 20:1472-1476
8. Schwartz RB, Jones KM, Chernoff DM, et al. Common carotid artery bifurcation: evaluation with spiral CT - work in progress. Radiology 1992; 185:513-519
9. Marks MP, Napel S, Jordan JE, Enzmann DR. Diagnosis of carotid artery disease: preliminary experience with maximum-intensity-projection spiral CT angiography. AJR 1993; 160:1267-1271
10. Cumming MJ, Morrow IM. Carotid artery stenosis: a prospective comparison of CT angiography and conventional angiography. AJR 1994; 163:517-523
11. Cinat M, Lane CT, Pham H, Lee A, Wilson SE, Gordon I. Helical CT angiography in the preoperative evaluation of carotid artery stenosis. J Vasc Surg 1998; 28:290-300
12. Marcus CD, Ladam-Marcus VJ, Bigot JL, Clement C, Baehrel B, Menanteau BP. Carotid arterial stenosis: evaluation at CT angiography with the volume-rendering technique. Radiology 1999; 211:775-780
13. Randoux B, Marro B, Koskas F, et al. Carotid artery stenosis: prospective comparison of CT, three-dimensional gadolinium-enhanced MR, and conventional angiography. Radiology 2001; 220:179-185
14. Albers GW, Caplan LR, Easton JD, et al. Transient ischemic attack: proposal for a new definition. N Engl J Med 2002; 347:1713-1716
15. Dix JE, Evans AJ, Kallmes DF, Sobel AH, Phillips CD. Accuracy and precision of CT angiography in a model of carotid artery bifurcation stenosis. Am J Neuroradiol 1997; 18:409-415
16. [No authors listed]. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med 1991; 325:445-453
17. Achenbach S, Moselewski F, Ropers D, et al. Detection of calcified and noncalcified coronary atherosclerotic plaque by contrast-enhanced, submillimeter multidetector spiral computed tomography: a segment-based comparison with intravascular ultrasound. Circulation 2004; 109:14-17
18. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 1:307-310
19. Raggi P, Callister TQ, Shaw LJ. Progression of coronary artery calcium and risk of first myocardial infarction in patients receiving cholesterol-lowering therapy. Arterioscler Thromb Vasc Biol 2004; 24:1272-1277
20. Callister TQ, Raggi P, Cooil B, Lippolis NJ, Russo DJ. Effect of HMG-CoA reductase inhibitors on coronary artery disease as assessed by electron-beam computed tomography. N Engl J Med 1998; 339:1972-1978
21. Achenbach S, Ropers D, Pohle K, et al. Influence of lipid-lowering therapy on the progression of coronary artery calcification: a prospective evaluation. Circulation 2002; 106:1077-1082
22. Wexler L, Brundage B, Crouse J, et al. Coronary artery calcification: pathophysiology, epidemiology, imaging methods, and clinical implications: a statement for health professionals from the American Heart Association Writing Group. Circulation 1996; 94:1175-1192
23. Huang H, Virmani R, Younis H, Burke AP, Kamm RD, Lee RT. The impact of calcification on the biomechanical stability of atherosclerotic plaques. Circulation 2001; 103:1051-1056
24. Hunt JL, Fairman R, Mitchell ME, et al. Bone formation in carotid plaques: a clinicopathological study. Stroke 2002; 33:1214-1219
25. Nandalur KR, Baskurt E, Hagspiel KD, Phillips CD, Kramer CM. Calcified carotid atherosclerotic plaque is associated less with ischemic symptoms than is noncalcified plaque on MDCT. AJR 2005; 184:295-298
26. Rumberger JA, Simons DB, Fitzpatrick LA, Sheedy PF, Schwartz RS. Coronary artery calcium area by electron-beam computed tomography and coronary atherosclerotic plaque area: a histopathologic correlative study. Circulation 1995; 92:2157-2162
27. Rumberger JA, Schwartz RS, Simons DB, Sheedy PF 3rd, Edwards WD, Fitzpatrick LA. Relation of coronary calcium determined by electron beam computed tomography and lumen narrowing determined by autopsy. Am J Cardiol 1994; 73:1169-1173
28. Glagov S, Weisenberg E, Zarins CK, Stankunavicius R, Kolettis GJ. Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med 1987; 316:1371-1375
29. Lu B, Zhuang N, Mao SS, et al. EKG-triggered CT data acquisition to reduce variability in coronary arterial calcium score. Radiology 2002; 224:838-844
30. Gillard JH. Imaging of carotid artery disease: from luminology to function? Neuroradiology 2003; 45:671-680
31. Hong C, Becker CR, Schoepf UJ, Ohnesorge B, Bruening R, Reiser MF. Coronary artery calcium: absolute quantification in nonenhanced and contrast-enhanced multi-detector row CT studies. Radiology 2002; 223:474-480