Cytotoxic activity of naphthoquinones with special emphasis on juglone and its 5-O-methyl derivative

Chemico-Biological Interactions

Volumn 184, Issue 3, 2010, Pages 439-448

  Montenegro, Raquel Carvalho ^a   Araújo, Ana Jérsia ^a   Molina, María Teresa ^b   Filho, José Delano Barreto Marinho ^a   Rocha, Danilo Damasceno ^a   Lopéz Montero, Eulogio ^b   Goulart, Marília O F ^c   Bento, E S ^c   Alves, Ana Paula Nunes Negreiros ^a   Pessoa, Cláudia ^a   de Moraes, Manoel Odorico ^a   Costa Lotufo, Letícia Veras ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b CSIC   (Spain)

^c FEDERAL UNIVERSITY OF ALAGOAS   (Brazil)

Author keywords

Apoptosis; Caspases; Cell cycle; Cytotoxicity; Juglone; Naphthoquinones

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; 2 BROMO 5 HYDROXY 1,4 NAPHTHOQUINONE; 2 BROMO 5 METHOXY 1,4 NAPHTHOQUINONE; 3 BROMO 5 HYDROXY 1,4 NAPHTHOQUINONE; 3 BROMO 5 METHOXY 1,4 NAPHTHOQUINONE; 5 ACETOXY 1,4 NAPHTHOQUINONE; 5 ACETOXY 2 BROMO 1,4 NAPHTHOQUINONE; 5 ACETOXY 3 BROMO 1,4 NAPHTHOQUINONE; 5 METHOXY 1,4 NAPHTHOQUINONE; CASPASE 3; CASPASE 7; CASPASE 8; DOXORUBICIN; JUGLONE; NAPHTHOQUINONE; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL MEMBRANE DEPOLARIZATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC 50; MITOCHONDRION; PERIPHERAL BLOOD MONONUCLEAR CELL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 7; CASPASE 8; CELL LINE, TUMOR; DNA FRAGMENTATION; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; MITOCHONDRIA; NAPHTHOQUINONES; PHOSPHATIDYLSERINES;

EID: 77949912839     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.01.041     Document Type: Article

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