Pachymic acid inhibits cell growth and modulates arachidonic acid metabolism in nonsmall cell lung cancer A549 cells

Molecular Carcinogenesis

Volumn 49, Issue 3, 2010, Pages 271-282

  Ling, Hui ^a   Jia, Xiaobin ^b   Zhang, Yaochun ^a   Gapter, Leslie A ^a   Lim, Yin Shan ^a   Agarwal, Rajesh ^c   Ng, Ka Yun ^a,d  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b KEY LABORATORY OF NEW DRUG DELIVERY SYSTEM OF CHINESE MATERIA MEDICA   (China)

^c UNIVERSITY OF COLORADO   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

COX 2; cPLA2; MAPK; NF B; Pachymic acid

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2; CYTOSOLIC PHOSPHOLIPASE A2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; PACHYMIC ACID; TRITERPENOID; UNCLASSIFIED DRUG; ARACHIDONIC ACID; MESSENGER RNA; PHOSPHOLIPASE A; TRITERPENE;

APOPTOSIS; ARACHIDONIC ACID METABOLISM; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFICACY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; CELL ADHESION; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; LUNG TUMOR; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; WESTERN BLOTTING;

APOPTOSIS; ARACHIDONIC ACID; BLOTTING, WESTERN; CARCINOMA, NON-SMALL-CELL LUNG; CELL ADHESION; CELL PROLIFERATION; CYCLOOXYGENASE 2; HUMANS; INTERLEUKIN-1BETA; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHOSPHOLIPASES A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRITERPENES; TUMOR CELLS, CULTURED;

EID: 77949883363     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20597     Document Type: Article

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