Melittin induces apoptotic features in Candida albicans

Biochemical and Biophysical Research Communications

Volumn 394, Issue 1, 2010, Pages 170-172

  Park, Cana ^a   Lee, Dong Gun ^a  

^a Kyungpook National University   (South Korea)

Author keywords

Antifungal effect; Antimicrobial peptide; Apoptosis; Melittin

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; DIHYDRORHODAMINE 123; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; MELITTIN; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE;

ANTIFUNGAL ACTIVITY; APOPTOSIS; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG SYNTHESIS; FLUORESCENCE MICROSCOPY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; STAINING;

ANTIFUNGAL AGENTS; APOPTOSIS; CANDIDA ALBICANS; CELL NUCLEUS; DNA FRAGMENTATION; MELITTEN; MICROSCOPY, FLUORESCENCE; PHOSPHATIDYLSERINES; REACTIVE OXYGEN SPECIES;

CANDIDA ALBICANS;

EID: 77949873917     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.02.138     Document Type: Article

References (26)

1. Zasloff M. Antimicrobial peptides of multicellular organisms. Nature 415 (2002) 389-395
2. Hancock R.E., and Sahl H.G. Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat. Biotechnol. 24 (2006) 1551-1557
3. Pereira H.A. Novel therapies based on cationic antimicrobial peptides. Curr. Pharm. Biotechnol. 7 (2006) 229-234
4. Jenssen H., Hamill P., and Hancock R.E. Peptide antimicrobial agents. Clin. Microbiol. Rev. 19 (2006) 491-511
5. Aerts A.M., Carmona-Gutierrez D., Lefevre S., Govaert G., François I.E., Madeo F., Santos R., Cammue B.P., and Thevissen K. The antifungal plant defensin RsAFP2 from radish induces apoptosis in a metacaspase independent way in Candida albicans. FEBS Lett. 583 (2009) 2513-2516
6. Morton C.O., Dos Santos S.C., and Coote P. An amphibian-derived, cationic, alpha-helical antimicrobial peptide kills yeast by caspase-independent but AIF-dependent programmed cell death. Mol. Microbiol. 65 (2007) 494-507
7. + efflux. Antimicrob. Agents Chemother. 52 (2008) 4081-4088
8. Habermann E. Bee and wasp venoms. Science 177 (1972) 314-322
9. Matsuzaki K., Yoneyama S., and Miyajima K. Pore formation and translocation of melittin. Biophys. J. 73 (1997) 831-838
10. Toraya S., Nagao T., Norisada K., Tuzi S., Saitô H., Izumi S., and Naito A. Morphological behavior of lipid bilayers induced by melittin near the phase transition temperature. Biophys. J. 89 (2005) 3214-3222
11. Merrifield R.B. Solid phase synthesis. Science 232 (1986) 341-347
12. Jungblut P., and Thiede B. Protein identification from 2-DE gels by MALDI mass spectrometry. Mass Spectrom. Rev. 16 (1997) 145-162
13. Madeo F., Fröhlich E., and Fröhlich K.U. A yeast mutant showing diagnostic markers of early and late apoptosis. J. Cell Biol. 139 (1997) 729-734
14. Phillips A.J., Sudbery I., and Ramsdale M. Apoptosis induced by environmental stresses and amphotericin B in Candida albicans. Proc. Natl. Acad. Sci. USA 100 (2003) 14327-14332
15. Park C., and Lee D.G. Fungicidal effect of antimicrobial peptide arenicin-1. Biochim. Biophys. Acta 1788 (2009) 1790-1796
16. Saugar J.M., Rodríguez-Hernández M.J., de la Torre B.G., Pachón-Ibañez M.E., Fernández-Reyes M., Andreu D., Pachón J., and Rivas L. Activity of cecropin A-melittin hybrid peptides against colistin-resistant clinical strains of Acinetobacter baumannii: molecular basis for the differential mechanisms of action. Antimicrob. Agents Chemother. 50 (2006) 1251-1256
17. Park S.C., Kim M.H., Hossain M.A., Shin S.Y., Kim Y., Stella L., Wade J.D., Park Y., and Hahm K.S. Amphipathic alpha-helical peptide, HP (2-20), and its analogues derived from Helicobacter pylori: pore formation mechanism in various lipid compositions. Biochim. Biophys. Acta 1778 (2008) 229-241
18. Lee M.T., Huang W.C., Chen F.Y., and Huang H.W. Mechanism and kinetics of pore formation in membranes by water-soluble amphipathic peptides. Proc. Natl. Acad. Sci. USA 105 (2008) 5087-5092
19. Kohanski M.A., Dwyer D.J., Hayete B., Lawrence C.A., and Collins J.J. A common mechanism of cellular death induced by bactericidal antibiotics. Cell 130 (2007) 797-810
20. Kohanski M.A., Dwyer D.J., Wierzbowski J., Cottarel G., and Collins J.J. Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death. Cell 135 (2008) 679-690
21. Fröhlich K.U., and Madeo F. Apoptosis in yeast-a monocellular organism exhibits altruistic behaviour. FEBS Lett. 473 (2000) 6-9
22. Pappas P.G., Rex J.H., Lee J., Hamill R.J., Larsen R.A., Powderly W., Kauffman C.A., Hyslop N., Mangino J.E., Chapman S., Horowitz H.W., Edwards J.E., and Dismukes W.E. NIAID mycoses study group, a prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients. Clin. Infect. Dis. 37 (2003) 634-643
23. Cabiscol E., Piulats E., Echave P., Herrero E., and Ros J. Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae. J. Biol. Chem. 275 (2000) 27393-27398
24. Wadskog I., Maldener C., Proksch A., Madeo F., and Adler L. Yeast lacking the SRO7/SOP1-encoded tumor suppressor homologue show increased susceptibility to apoptosis-like cell death on exposure to NaCl stress. Mol. Biol. Cell 15 (2004) 1436-1444
25. Ludovico P., Sousa M.J., Silva M.T., Leão C., and Côrte-Real M. Saccharomyces cerevisiae commits to a programmed cell death process in response to acetic acid. Microbiology 147 (2001) 2409-2415
26. Ribeiro G.F., Côrte-Real M., and Johansson B. Characterization of DNA damage in yeast apoptosis induced by hydrogen peroxide, acetic acid, and hyperosmotic shock. Mol. Biol. Cell 17 (2006) 4584-4591