Yeast Lacking the SRO7/SOP1-encoded Tumor Suppressor Homologue Show Increased Susceptibility to Apoptosis-like Cell Death on Exposure to NaCl Stress

Molecular Biology of the Cell

Volumn 15, Issue 3, 2004, Pages 1436-1444

  Wadskog, Ingrid ^a   Maldener, Corinna ^b   Proksch, Astrid ^b   Madeo, Frank ^b   Adler, Lennart ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM CHLORIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CHROMATIN CONDENSATION; DNA STRAND BREAKAGE; GENE; GENE DELETION; GENE MUTATION; GENETIC SUSCEPTIBILITY; GROWTH INHIBITION; MARKER GENE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; TUMOR SUPPRESSOR GENE; YCA1 GENE; YEAST;

APOPTOSIS; CARRIER PROTEINS; CASPASES; CELL DEATH; DNA FRAGMENTATION; GENES, TUMOR SUPPRESSOR; MUTATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SODIUM CHLORIDE;

ANIMALIA;

EID: 1542373732     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E03-02-0114     Document Type: Article

References (43)

1. Albertyn, J., Hohmann, S., Thevelein, J.M., and Prior, B.A. (1994). GPD1, which encodes glycerol-3-phosphate dehydrogenase is essential for growth under osmotic stress in Saccharomyces cerevisiae and its expression is regulated by the high-osmolarity glycerol response pathway. Mol. Cell. Biol. 14, 4135-4144.
2. Ansell, R., Granath, K., Hohmann, S., Thevelein, J., and Adler, L. (1997). The two isoenzymes for yeast NAD-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2, have distinct roles in osmoadaption and redox regulation. EMBO J. 16, 2179-2187.
3. Beers, E.P., and McDowell, J.M. (2001). Regulation and execution of programmed cell death in response to pathogens, stress and developmental cues. Curr. Opin. Plant Biol. 4, 561-567.
4. Bilder, D., Li, M., and Perrimon, N. (2000). Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science 289, 113-116.
5. De Lorenzo, C., Strand, D., and Mechler, B.M. (1999). Requirement of Drosophila I(2)gl function for survival of the germline cells and organization of the follicle cells in a columnar epithelium during oogenesis. Int. J. Dev. Biol. 43, 207-217.
6. de Nadal, E., Calero, F., Ramos, J., and Arino, J. (1999). Biochemical and genetic analyses of the role of yeast casein kinase 2 in salt tolerance. J. Bacteriol. 181, 6456-6462.
7. Drees, B.L., et al. (2001). A. protein interaction map for cell polarity development. J. Cell Biol. 154, 549-571.
8. +-ATPases. J. Biol. Chem. 276, 29617-19620.
9. Engelberg-Kulka, H., and Glaser, G. (1999). Addiction modules and programmed cell death and antideath in bacterial cultures. Annu. Rev. Microbiol. 53, 43-70.
10. Fröhlich, K.U., and Madeo, F. (2000). Apoptosis in yeast - a monocellular organism exhibits altruistic behaviour. FEBS Lett. 473, 6-9.
11. Fröhlich, K.U., and Madeo, F. (2001). Apoptosis in yeast: a new model for aging research. Exp. Gerontol. 37, 27-31.
12. Gateff, E. (1978). Malignant neoplasms of genetic origin in Drosophila melanogaster. Science 200, 1448-1459.
13. Haro, R., Garciadeblas, B., and Rodriguéz-Navarro, A. (1991). A novel P-type ATPase from yeast involved in sodium transport. FEBS Lett. 291, 189-191.
14. Huh, G.H., Damsz, B., Matsumoto, T.K., Reddy, M.P., Rus, A.M., Ibeas, J.I., Narasimhan, M.L., Bressan, R.A., and Hasegawa, P.M. (2002). Salt causes ion disequilibrium-induced programmed cell death in yeast and plants. Plant J. 29, 649-659.
15. Humbert, P., Russell, S., and Richardson, H. (2003). Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer. Bioessays 25, 542-553.
16. Joza, N., Kroemer, G., and Penninger, J.M. (2002). Genetic analysis of the mammalian cell death machinery. Trends Genet. 18, 142-149.
17. Katsuhara, M. (1997). Apoptosis like cell death in barley roots under salt stress. Plant Cell Physiol. 38, 1091-1093.
18. Kerr, J.F. (2002). History of the events leading to the formulation of the apoptosis concept. Toxicology 181-182, 471-474.
19. Larsson, K., Böhl, F., Sjöström, I., Akhtar, N., Strand, D., Mechler, B., Grabowski, R., and Adler, L. (1998). The Saccharomyces cerevisiae SOP1 and SOP2 genes, which act in cation homeostasis, can be functionally substituted by the Drosophila lethal(2)giant larvae tumor suppressor gene. J. Biol. Chem. 273, 33610-33618.
20. +) complements an osmosensitive mutant of Saccharomyces cerevisiae. Mol. Microbiol. 10, 1101-1111.
21. Latterich, M., Fröhlich, K.U., and Schekman, R. (1995). Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes. Cell 82, 885-893.
22. Laun, P., Pichova, A., Madeo, F., Fuchs, J., Ellinger, A., Kohlwein, S., Dawes, I., Fröhlich, K.U., and Breitenbach, M. (2001). Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis. Mol. Microbiol. 39, 1166-1173.
23. Lehman, K., Rossi, G., Adamo, J.E., and Brennwald, P. (1999). Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9. J. Cell Biol. 146, 125-140.
24. Madeo, F., Fröhlich, E., and Fröhlich, K.U. (1997). A yeast mutant showing diagnostic markers of early and late apoptosis. J. Cell Biol. 139, 729-734.
25. Madeo, F., Fröhlich, E., Ligr, M., Grey, M., Sigrist, S.J., Wolf, D.H., and Fröhlich, K.U. (1999). Oxygen stress: a regulator of apoptosis in yeast. J. Cell Biol. 145, 757-767.
26. Madeo, F., et al. (2002). A caspase-related protease regulates apoptosis in yeast. Mol. Cell 9, 911-917.
27. Matsuyama, S., Nouraini, S., and Reed, J.C. (1999). Yeast as a tool for apoptosis research. Curr. Opin. Microbiol. 2, 618-623.
28. Ohshiro, T., Yagami, T., Zhang, C., and Matsuzaki, F. (2000). Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast. Nature 408, 593-596.
29. Peng, C.Y., Manning, L., Albertson, R., and Doe, C.Q. (2000). The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts. Nature 408, 596-600.
30. Qi, H., Li, T.-K., Kuo, D., Nur-El-Kamal, A., and Li, L.F. (2003). Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast. J. Biol. Chem. 278, 15136-15141.
31. Serrano, R., et al. (1999). A glimpse of the mechanisms of ion homeostasis during salt stress. J. Exp. Bot. 50, 1023-1036.
32. Severin, F.F., and Hyman, A.A. (2002). Pheromone Induces programmed cell death in S. cerevisiae. Curr. Biol. 12, R233-R235.
33. Uetz, P., et al. (2000). A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403, 623-627.
34. Uren, A.G., and Vaux, D.L. (1996). Molecular and clinical aspects of apoptosis. Pharmacol. Ther. 72, 37-50.
35. Wadskog, I., and Adler, L. (2003). Ion homeostasis in Saccharomyces cerevisiae under NaCl stress. In: S. Hohmann and P. Mager, eds. Topics in current genetics: yeast stress responses (vol. 1). Berlin, Springer-Verlag, 201-239.
36. Wadskog, I. (2003). Functional studies of the Sro yeast homologues of the Drosophila lethal(2) giant larvae tumor suppressor. [Ph.D. thesis]. Göteborg, Sweden: Götenborg University.
37. Vaux, D.L., and Korsmeyer, S.J. (1999). Cell death in development. Cell 96, 245-254.
38. Weaver, V.M., Lelievre, S., Lakins, J.N., Chrenek, M.A., Jones, J.C., Giancotti, F., Werb, Z., and Bissell, M.J. (2002). beta4 Integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell 2, 205-216.
39. Webb, S., Harrison, D.J., and Wyllie, A.H. (1997). Apoptosis: an overview of the process and its relevance in disease. Adv. Pharmacol. 41, 1-34.
40. + pump in the yeast plasma membrane. EMBO J. 14, 3870-3882.
41. Wodarz, A. (2000). Tumor suppressors: linking cell polarity and growth control. Curr. Biol. 10, R624-R626.
42. Wyllie, A.H., et al. (1999). Apoptosis and carcinogenesis. Br. J. Cancer 80, 34-37.
43. Wyllie, A.H., Kerr, J.F., and Currie, A.R. (1980). Cell death: the significance of apoptosis. Int. Rev. Cytol. 68, 251-306.