Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy

Nature Chemical Biology

Volumn 6, Issue 4, 2010, Pages 273-275

  Hagel, Jillian M ^a   Facchini, Peter J ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; CODEINE DEMETHYLASE; CYTOCHROME P450; DIOXYGENASE; FERROUS ION; MORPHINE; O DEMETHYLASE; OPIATE; POLYHISTIDINE TAG; THEBAINE 6 O DEMETHYLASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BIOSYNTHESIS; CHEMICAL STRUCTURE; DEMETHYLATION; ENZYME ACTIVITY; ENZYME METABOLISM; ENZYME SUBSTRATE; ESCHERICHIA COLI; EXTRACTION; FUNCTIONAL GENOMICS; GENE CONSTRUCT; GENE SILENCING; HYDROXYLATION; ION PAIR CHROMATOGRAPHY; PHYLOGENETIC TREE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

MAMMALIA; PAPAVER SOMNIFERUM;

EID: 77949847651     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.317     Document Type: Article

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